Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Cardiovascular Risk Factor Trajectories Since Childhood and Cognitive Performance in Midlife The Cardiovascular Risk in Young Finns Study (2021)
- Circulation
(A1 Refereed original research article in a scientific journal) - Carotid artery longitudinal wall motion alterations associated with metabolic syndrome and insulin resistance (2021)
- Clinical Physiology and Functional Imaging
(A1 Refereed original research article in a scientific journal) - Childhood and Adulthood Passive Smoking and Nonalcoholic Fatty Liver in Midlife: A 31-year Cohort Study (2021)
- American Journal of Gastroenterology
(A1 Refereed original research article in a scientific journal) - Childhood and long-term dietary calcium intake and adult cardiovascular risk in a population with high calcium intake (2021)
- Clinical Nutrition
(A1 Refereed original research article in a scientific journal) - Childhood exposure to parental smoking and life-course overweight and central obesity (2021)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Corrigendum to “Sleep and cardiometabolic health in children and adults: examining sleep as a component of the 24-hour day” [Sleep Med 78 (2020) 63–74] (Sleep Medicine (2021) 78 (63–74), (S1389945720305414), (10.1016/j.sleep.2020.12.001)) (2021)
- Sleep Medicine
(Other publication) - Dietary Pattern Trajectories from Youth to Adulthood and Adult Risk of Impaired Fasting Glucose: A 31-year Cohort Study (2021)
- Journal of Clinical Endocrinology and Metabolism
(A1 Refereed original research article in a scientific journal) - Diet quality trajectories and cardiovascular phenotypes/metabolic syndrome risk by 11-12 years (2021)
- International Journal of Obesity
(A1 Refereed original research article in a scientific journal) - Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts (2021)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Fatty liver index predicts incident risk of prediabetes, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) (2021)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries (2021)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Hyperkolesterolemian uudet hoitosuositukset (2021)
- Erikoislääkäri
(D1 Article in a professional journal) - IDO activity forecasts obesity in males and premenopausal females in a 10-year follow-up study:The Cardiovascular Risk in Young Finns Study (2021)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Influence of early-life body mass index and systolic blood pressure on left ventricle in adulthood - the Cardiovascular Risk in Young Finns Study (2021)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Influence of early life risk factors and lifestyle on systemic vascular resistance in later adulthood: the cardiovascular risk in young Finns study (2021)
- Blood Pressure
(A1 Refereed original research article in a scientific journal) - Influential Periods in Longitudinal Clinical Cardiovascular Health Scores (2021)
- American Journal of Epidemiology
(A1 Refereed original research article in a scientific journal) - Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs (2021)
- Clinical Epigenetics
(A1 Refereed original research article in a scientific journal) - Modest decrease in severity of obesity in adolescence associates with low arterial stiffness (2021)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Modular genome-wide gene expression architecture shared by early traits of osteoporosis and atherosclerosis in the Young Finns Study (2021)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Physical inactivity from youth to adulthood and adult cardiometabolic risk profile (2021)
- Preventive Medicine
(A1 Refereed original research article in a scientific journal)