Kirsi Laitinen
PhD, authorized nutritionist
Nutrition and Food Research Center, Director kirsi.laitinen@utu.fi +358 29 450 2428 +358 50 379 7010 Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0001-5245-8118 |
nutrition; clinical trials; early life events; E-health; pregnancy; children; obesity; gestational diabetes; allergy; diet; lipids; microbiome; metabolomics
Kirsi Laitinen is Professor at the University of Turku, Institute of Biomedicine, Integrative Physiology and Pharmacology Unit and Director of Nutrition and Food Research Center, Turku, Finland. She completed her PhD in human nutrition at the University of Southampton, UK, in 2000 and was inspired by the tremendous impacts nutrition may have on human health. She has since completed a series of studies in Finland with particular interest in exploring the impacts of nutritional determinants, including probiotics, during pregnancy and breastfeeding on maternal and child health. To date she has contributed about 180 scientific peer reviewed publications to the nutrition field.
Her research centers on relations amongst dietary components, metabolic markers and gut microbiota with health, the main focus being in early nutrition (mother and child), gut health and Western diseases including obesity, gestational diabetes, type 2 diabetes and allergy. One field of study is diagnostics involving early biomarkers (microbiota, serum). The active dietary ingredients studied include probiotics and lipids. She has also on-going studies related to dietary intake as well as the development and testing of methods for dietary intake assessment in different groups of individuals, and eating behaviour and quality of life, with the primary focus groups being children and women during and after pregnancy.
https://sites.utu.fi/nutritionresearch/en/
Worldwide burden of life-style related diseases is tremendous, and vastly contributes to co-morbidities and costs of the society. The impact of the early nutritional environment during pregnancy, lactation and infancy is of vast importance for the health of both the mother and the child. One out of every three pregnant women is overweight or obese. Obesity predisposes women to an increased risk of complications during pregnancy and beyond. One manifestation is an increased incidence of gestational diabetes. Gestational diabetes in turn predisposes to the development of postpartum type two diabetes and cardiovascular complications, and increases the risk of metabolic disorders and overweight in the child, which continues until adulthood. Pregnancy may be taken as a window of opportunity, defining the health of both the mother and child.
Further, the dietary habits learned in childhood may define the health even in adulthood. Nutrition as a child has been linked to obesity and cardiovascular risk markers in later life. The knowledge how diet and nutritional status in childhood are interrelated and again contribute to health are still not clearly defined. On the other hand, the existing knowledge on diet-health relations, that are already basis for dietary reference values for general population, may be utilized in nutrition and health counselling to advance public health status. For this, we need new means, like short methods for dietary evaluation and E-health approaches that will be developed in the project.
The goal of the research group is to provide scientific basis for the relationship between diet, other lifestyle habits, microbiota and health, focusing on the effects of maternal nutrition on both maternal and child health and to develop new tools to advance lifestyle changes.
-Pedagogic qualification of a teacher, Faculty of Education, University of Turku, Turku, Finland, 2010 (60 credits).
-More than twenty years’ experience in teaching both at undergraduate and postgraduate level (at the University of Turku since 2000-) involving curriculum planning and implementation, development of teaching including several pedagogic approaches like problem based learning and use of internet based learning platform. The primary area of teaching is human nutrition.
-Theses supervision: 16 PhD students (nine on-going).
- Perinatal nutrition impacts on the functional development of the visual tract in infants (2019)
- Pediatric Research
(A1 Refereed original research article in a scientific journal) - The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children (2019)
- European Journal of Nutrition
(A1 Refereed original research article in a scientific journal) - Usual dietary treatment of gestational diabetes mellitus assessed after control diet in randomized controlled trials: subanalysis of a systematic review and meta-analysis (2019)
- Acta Diabetologica
(A2 Refereed review article in a scientific journal ) - Double-Blind Randomized Placebo Controlled Trial Demonstrating Serum Cholesterol Lowering Efficacy of a Smoothie Drink with Added Plant Stanol Esters in an Indonesian Population (2018)
- Cholesterol
(A1 Refereed original research article in a scientific journal) - Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight (2018)
- Diabetes Care
(A2 Refereed review article in a scientific journal ) - Overweight and obesity status in pregnant women are related to intestinal microbiota and serum metabolic and inflammatory profiles (2018)
- Clinical Nutrition
(A1 Refereed original research article in a scientific journal) - The impact of probiotics and n-3 long-chain polyunsaturated fatty acids on intestinal permeability in pregnancy: a randomised clinical trial (2018)
- Beneficial Microbes
(A1 Refereed original research article in a scientific journal) - Adherence to dietary recommendations modifies gut microbiota richness and composition during pregnancy (2017)
- Annals of Nutrition and Metabolism
(Other publication) - Cholesterol lowering efficacy of plant stanol ester in a new type of product matrix, a chewable dietary supplement (2017)
- Journal of Functional Foods
(A1 Refereed original research article in a scientific journal) - Dietary intake of fat and fibre according to reference values relates to higher gut microbiota richness in overweight pregnant women (2017)
- British Journal of Nutrition
(A1 Refereed original research article in a scientific journal) - Dietary intake of fibre and gut microbiota is related to lower level of glycoprotein acetylation, a marker of low-grade inflammation, in overweight pregnant women (2017)
- Annals of Nutrition and Metabolism
(Other publication) - Evaluation of serum zonulin for use as an early predictor for gestational diabetes (2017)
- Nutrition and Diabetes
(A1 Refereed original research article in a scientific journal) - Gut microbiota aberrations precede diagnosis of gestational diabetes mellitus (2017)
- Acta Diabetologica
(A1 Refereed original research article in a scientific journal) - Impact of Early Nutrition on Intestinal Microbiome: Effects on Immunity and Long-Term Health (2017) Early Nutrition and Long-Term Health - Mechanisms, Consequences, and Opportunities Kirsi Laitinen, Kati Mokkala, Marko Kalliomäki
(A3 Refereed book chapter or chapter in a compilation book) - Increased intestinal permeability, measured by serum zonulin, is associated with metabolic risk markers in overweight pregnant women (2017)
- Metabolism
(A1 Refereed original research article in a scientific journal) - Opportunities for probiotics and polyunsaturated fatty acids to improve metabolic health of overweight pregnant women (2017)
- Beneficial Microbes
(A2 Refereed review article in a scientific journal ) - Relation of maternal dietary and probiotic intervention during pregnancy to the risk of atopic eczema and asthma in the offspring by the 4 years of age (2017)
- Allergy
(Other publication) - Simple dietary criteria to improve serum n-3 fatty acid levels of mothers and their infants (2017)
- Public Health Nutrition
(A1 Refereed original research article in a scientific journal) - Bifidobacterium lactis 420 and fish oil enhance intestinal epithelial integrity in Caco-2 cells (2016)
- Nutrition Research
(A1 Refereed original research article in a scientific journal) - Diet composition and gut microbiota composition of overweight pregnant women at risk of gestational diabetes are related to intestinal permeability (2016)
- Diabetologia
(Other publication)