Olli Raitakari
 MD/PhD


olli.raitakari@utu.fi

+358 29 450 2304

Kiinamyllynkatu 10

Turku


ORCID identifier: https://orcid.org/0000-0001-9365-3702

Areas of expertise
cardiovascular and metabolic diseases; risk factors; vascular epidemiology; genetic epidemiology; epidemiology; dietary intervention; cohort studies; follow-up studies

Biography

EDUCATION AND DEGREES
 
2001   Docent in Clinical Physiology
1997-1999  Postdoc training, Royal Prince Alfred Hospital, Sydney, Australia
1997   Docent in Epidemiology
1996   Specialist in Clinical Physiology 
1995   Doctorate, PhD
1989   Licentiate in Medicine, MD

CURRENT POSITIONS

2017-                 Professor in Cardiovascular Medicine, Director of the Research Centre of Applied and 
                          Preventive Cardiovascular Medicine, University of Turku, Finland                         

 

PAST POSITIONS

2012-2016                          Academy Professor, University of Turku

2007-2016                          Professor in Cardiovascular Medicine (part time), University of Turku

2007-2008                          Senior Scientist Grant, Academy of Finland

2004-2016                          Chief Physician, Department of Clinical Physiology and Nuclear Medicine, Turku
                                           University Hospital (leave of absence 2012-2016)

2002-2004                          Consultant in Clinical Physiology and Nuclear Medicine, Turku University Hospital

2002 (1 mo)                        Head of Nuclear Medicine Department, Turku University Hospital

2000-2003 (3 mo)               Head of Clinical Physiology Department, Turku University Hospital

2000-2005                          Senior Fellow Post, Academy of Finland

1998-2000                          Postdoctoral Research Post, Academy of Finland

1996-1997                          Consultant in Clinical Physiology, Turku University Hospital

1991-1996                          Positions as Resident in Clinical Chemistry, Nuclear Medicine, and Clinical 
                                           Physiology, Turku University Hospital

1988-1990                          Positions as General Practioner and Resident in Internal Medicine or Surgery




Research

Evidence suggest that many non-communicable disease outcomes have roots in childhood and may even stem of adverse ancestral exposures. Improved knowledge how various ancestral and early-life exposures lead to adult disease outcomes is essential in developing better preventive practices and policies that lead to improved public health. My mission has been to contribute to this knowledge-base by working in epidemiologic cohort studies with follow-up from childhood to adulthood. I am the Principal Investigator of the Cardiovascular Risk in Young Finns Study (YFS), the largest study in Europe with a follow-up of cardiovascular risk factors from childhood to adulthood. I am also the Director of the STRIP Study, which is a leading long-term pediatric dietary intervention study testing the hypothesis that modifying the fat quality diet will have beneficial effects on cardiovascular risk early in life. During the past years, I have organized several field studies in these cohorts, and introduced novel technologies, such as imaging studies, genetic epidemiology methods and metabolomics approaches in these unique population resources. Our research has contributed to the understanding of pre-clinical development of atherosclerosis in children and young adults, including the effects of diet, life-style, metabolic risk factors, psychological traits and psychosocial factors, inflammation, hormones and genetic markers. For example, by applying non-invasive imaging methods in the Young Finns Study, we have demonstrated that exposure to adverse lipids, elevated blood pressure and obesity in childhood is related to atherosclerosis development in adulthood (JAMA 2003). Subsequent work stemmed from this initial observation has led to numerous original publications that have shown in detail how exposure to a large range of aetiogenic factors early in life contribute to the development of cardio-metabolic outcomes in adulthood. For example, by pooling international i3C Consortium data, we have demonstrated that overweight or obese children who became non-obese by adulthood had similar risks of many cardio-metabolic adult outcomes as individuals who were never obese (NEJM 2011). Thus, the results of our studies have clearly demonstrated that individual’s exposure to various stressors in early life is contributing to his/her adult phenotype and disease risk. The results have had significant impact on preventive practices. As a concrete demonstration of the international recognition and impact of my team’s work, many of our studies are widely cited in all updated paediatric guidelines on cardiovascular prevention both in Europe and in US.



Publications
  
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  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors  (2019)  
    • Nature Genetics
     Warrington N.M., Beaumont R.N., Horikoshi M., Day F.R., Helgeland Ø., Laurin C., Bacelis J., Peng S., Hao K., Feenstra B., Wood A.R., Mahajan A., Tyrrell J., Robertson N.R., Rayner N.W., Qiao Z., Moen G.-H., Vaudel M., Marsit C.J., Chen J., Nodzenski M., Schnurr T.M., Zafarmand M.H., Bradfield J.P., Grarup N., Kooijman M.N., Li-Gao R., Geller F., Ahluwalia T.S., Paternoster L., Rueedi R., Huikari V., Hottenga J.-J., Lyytikäinen L.-P., Cavadino A., Metrustry S., Cousminer D.L., Wu Y., Thiering E., Wang C.A., Have C.T., Vilor-Tejedor N., Joshi P.K., Painter J.N., Ntalla I., Myhre R., Pitkänen N., van Leeuwen E.M., Joro R., Lagou V., Richmond R.C., Espinosa A., Barton S.J., Inskip H.M., Holloway J.W., Santa-Marina L., Estivill X., Ang W., Marsh J.A., Reichetzeder C., Marullo L., Hocher B., Lunetta K.L., Murabito J.M., Relton C.L., Kogevinas M., Chatzi L., Allard C., Bouchard L., Hivert M.-F., Zhang G., Muglia L.J., Heikkinen J., Morgen C.S., van Kampen A.H.C., van Schaik B.D.C., Mentch F.D., Langenberg C., Luan J., Scott R.A., Zhao J.H., Hemani G., Ring S.M., Bennett A.J., Gaulton K.J., Fernandez-Tajes J., van Zuydam N.R., Medina-Gomez C., de Haan H.G., Rosendaal F.R., Kutalik Z., Marques-Vidal P., Das S., Willemsen G., Mbarek H., Müller-Nurasyid M., Standl M., Appel E.V.R., Fonvig C.E., Trier C., van Beijsterveldt C.E.M., Murcia M., Bustamante M., Bonas-Guarch S., Hougaard D.M., Mercader J.M., Linneberg A., Schraut K.E., Lind P.A., Medland S.E., Shields B.M., Knight B.A., Chai J.-F., Panoutsopoulou K., Bartels M., Sánchez F., Stokholm J., Torrents D., Vinding R.K., Willems S.M., Atalay M., Chawes B.L., Kovacs P., Prokopenko I., Tuke M.A., Yaghootkar H., Ruth K.S., Jones S.E., Loh P.-R., Murray A., Weedon M.N., Tönjes A., Stumvoll M., Michaelsen K.F., Eloranta A.-M., Lakka T.A., van Duijn C.M., Kiess W., Körner A., Niinikoski H., Pahkala K., Raitakari O.T., Jacobsson B., Zeggini E., Dedoussis G.V., Teo Y.-Y., Saw S.-M., Montgomery G.W., Campbell H., Wilson J.F., Vrijkotte T.G.M., Vrijheid M., de Geus E.J.C.N., Hayes M.G., Kadarmideen H.N., Holm J.-C., Beilin L.J., Pennell C.E., Heinrich J., Adair L.S., Borja J.B., Mohlke K.L., Eriksson J.G., Widén E.E., Hattersley A.T., Spector T.D., Kähönen M., Viikari J.S., Lehtimäki T., Boomsma D.I., Sebert S., Vollenweider P., Sørensen T.I.A., Bisgaard H., Bønnelykke K., Murray J.C., Melbye M., Nohr E.A., Mook-Kanamori D.O., Rivadeneira F., Hofman A., Felix J.F., Jaddoe V.W.V., Hansen T., Pisinger C., Vaag A.A., Pedersen O., Uitterlinden A.G., Järvelin M.-R., Power C., Hyppönen E., Scholtens D.M., Lowe W.L., Jr, Davey Smith G., Timpson N.J., Morris A.P., Wareham N.J., Hakonarson H., Grant S.F.A., Frayling T.M., Lawlor D.A., Njølstad P.R., Johansson S., Ong K.K., McCarthy M.I., Perry J.R.B., Evans D.M., Freathy R.M.; EGG Consortium
    (    A1 Refereed original research article in a scientific journal)


  • Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits  (2019)  
    • Nature Communications
     Eleonora Porcu, Sina Rüeger, Kaido Lepik; eQTLGen Consortium; BIOS Consortium; Federico A. Santoni, Alexandre Reymond, Zoltán Kutalik
    (    A1 Refereed original research article in a scientific journal)


  • Migraine polygenic risk score associates with efficacy of migraine-specific drugs  (2019)  
    • Neurology-Genetics
     Kogelman LJA, Esserlind AL, Christensen AF, Awasthi S, Ripke S, Ingason A, Davidsson OB, Erikstrup C, Hjalgrim H, Ullum H, Olesen J, Hansen TF, Gudbjartsson D, Gastafsson O, Stefansson K, Stefansson H, Porsteinsdottir U, Andersen S, Banasik K, Brunak S, Buil A, Burgdorf K, Gregor J, Jennum P, Nielsen KR, Nyegaard M, Paarup HM, Pedersen OB, Sorensen E, Werge T, Anttila V, Artto V, Belin AC, de Boer I, Boomsma DI, Borte S, Chasman DI, Cherkas L, Cormand B, Cuenca-Leon E, Davey-Smith G, Dichgans M, van Duijn C, Esko T, Ferrari M, Frants RR, Freilinger T, Furlotte N, Gormley P, Griffiths L, Hamalainen E, Hiekkala M, Ikram MA, Jarvelin MR, Kajanne R, Kallela M, Kaprio J, Kaunisto M, Kubisch C, Kurki M, Kurth T, Launer L, Lehtimaki T, Lessel D, Ligthart L, Litterman N, van den Maagdenberg A, Macaya A, Malik R, Mangino M, McMahon G, Muller-Myhsok B, Neale BM, Northover C, Nyholt DR, Palotie A, Palta P, Pedersen L, Pedersen N, Posthuma D, Pozo-Rosich P, Pressman A, Raitakari O, Schurks M, Sintas C, Steinberg S, Strachan D, Terwindt G, Vila-Pueyo M, Wessman M, Winsvold BS, Zhao HY, Zwart JA, Zwart JA, Zhao HY, Winsvold BS
    (    A1 Refereed original research article in a scientific journal)


  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions  (2019)  
    • American Journal of Epidemiology
     de Vries P.S., Brown M.R., Bentley A.R., Sung Y.J., Winkler T.W., Ntalla I., Schwander K., Kraja A.T., Guo X., Franceschini N., Cheng C.-Y., Sim X., Vojinovic D., Huffman J.E., Musani S.K., Li C., Feitosa M.F., Richard M.A., Noordam R., Aschard H., Bartz T.M., Bielak L.F., Deng X., Dorajoo R., Lohman K.K., Manning A.K., Rankinen T., Smith A.V., Tajuddin S.M., Evangelou E., Graff M., Alver M., Boissel M., Chai J.F., Chen X., Divers J., Gandin I., Gao C., Goel A., Hagemeijer Y., Harris S.E., Hartwig F.P., He M., Horimoto A.R.V.R., Hsu F.-C., Jackson A.U., Kasturiratne A., Komulainen P., Kühnel B., Laguzzi F., Lee J.H., Luan J., Lyytikäinen L.-P., Matoba N., Nolte I.M., Pietzner M., Riaz M., Said M.A., Scott R.A., Sofer T., Stančáková A., Takeuchi F., Tayo B.O., van der Most P.J., Varga T.V., Wang Y., Ware E.B., Wen W., Yanek L.R., Zhang W., Zhao J.H., Afaq S., Amin N., Amini M., Arking D.E., Aung T., Ballantyne C., Boerwinkle E., Broeckel U., Campbell A., Canouil M., Charumathi S., Chen Y.-D.I., Connell J.M., de Faire U., de Las Fuentes L., de Mutsert R., de Silva H.J., Ding J., Dominiczak A.F., Duan Q., Eaton C.B., Eppinga R.N., Faul J.D., Fisher V., Forrester T., Franco O.H., Friedlander Y., Ghanbari M., Giulianini F., Grabe H.J., Grove M.L., Gu C.C., Harris T.B., Heikkinen S., Heng C.-K., Hirata M., Hixson J.E., Howard B.V., Ikram M.A., InterAct Consortium, Jacobs D.R., Johnson C., Jonas J.B., Kammerer C.M., Katsuya T., Khor C.C., Kilpeläinen T.O., Koh W.-P., Koistinen H.A., Kolcic I., Kooperberg C., Krieger J.E., Kritchevsky S.B., Kubo M., Kuusisto J., Lakka T.A., Langefeld C.D., Langenberg C., Launer L.J., Lehne B., Lemaitre R.N., Li Y., Liang J., Liu J., Liu K., Loh M., Louie T., Mägi R., Manichaikul A.W., McKenzie C.A., Meitinger T., Metspalu A., Milaneschi Y., Milani L., Mohlke K.L., Mosley T.H., Mukamal K.J., Nalls M.A., Nauck M., Nelson C.P., Sotoodehnia N., O'Connell J.R., Palmer N.D., Pazoki R., Pedersen N.L., Peters A., Peyser P.A., Polasek O., Poulter N., Raffel L.J., Raitakari O.T., Reiner A.P., Rice T.K., Rich S.S., Robino A., Robinson J.G., Rose L.M., Rudan I., Schmidt C.O., Schreiner P.J., Scott W.R., Sever P., Shi Y., Sidney S., Sims M., Smith B.H., Smith J.A., Snieder H., Starr J.M., Strauch K., Tan N., Taylor K.D., Teo Y.Y., Tham Y.C., Uitterlinden A.G., van Heemst D., Vuckovic D., Waldenberger M., Wang L., Wang Y., Wang Z., Wei W.B., Williams C., Wilson G., Wojczynski M.K., Yao J., Yu B., Yu C., Yuan J.-M., Zhao W., Zonderman A.B., Becker D.M., Boehnke M., Bowden D.W., Chambers J.C., Deary I.J., Esko T., Farrall M., Franks P.W., Freedman B.I., Froguel P., Gasparini P., Gieger C., Horta B.L., Kamatani Y., Kato N., Kooner J.S., Laakso M., Leander K., Lehtimäki T., Lifelines Cohort, Groningen, The Netherlands (Lifelines Cohort Study), Magnusson P.K.E., Penninx B., Pereira A.C., Rauramaa R., Samani N.J., Scott J., Shu X.-O., van der Harst P., Wagenknecht L.E., Wang Y.X., Wareham N.J., Watkins H., Weir D.R., Wickremasinghe A.R., Zheng W., Elliott P., North K.E., Bouchard C., Evans M.K., Gudnason V., Liu C.-T., Liu Y., Psaty B.M., Ridker P.M., van Dam R.M., Kardia S.L.R., Zhu X., Rotimi C.N., Mook-Kanamori D.O., Fornage M., Kelly T.N., Fox E.R., Hayward C., van Duijn C.M., Tai E.S., Wong T.Y., Liu J., Rotter J.I., Gauderman W.J., Province M.A., Munroe P.B., Rice K., Chasman D.I., Cupples L.A., Rao D.C., Morrison A.C.
    (    A1 Refereed original research article in a scientific journal)


  • Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids  (2019)  
    • Nature Genetics
     Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo XQ, Liu JM, Lu YC, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li CW, Feitosa MF, Richard MA, Noordam R, Baker J, Chen GJ, Aschard H, Bartz TM, Ding JZ, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He MA, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kuhnel B, Leander K, Lin KH, Luan JA, Lyytikainen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancakova A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang YJ, Ware EB, Wen WQ, Xiang YB, Yanek LR, Zhang WH, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YDI, Christensen K, Concas MP, Connell JM, de las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA, Jia YC, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpelainen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li YZ, Liang JJ, Lin S, Liu CT, Liu JJ, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Magi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O'Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renstrom F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG, van Heemst D, Waldenberger M, Wang HM, Wang L, Wang LH, Wei WB, Williams CA, Wilson G, Wojczynski MK, Yao J, Young K, Yu CZ, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JMJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimaki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu TC, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu YM, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu XF, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA
    (    A1 Refereed original research article in a scientific journal)


  • Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration  (2019)  
    • Nature Communications
     Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderman AB, Becker DM, Elliott P, Esko T, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, North KE, Penninx BWJH, Vollenweider P, Wagenknecht LE, Wu T, Xiang YB, Zheng W, Arnett DK, Bouchard C, Evans MK, Gudnason V, Kardia S, Kelly TN, Kritchevsky SB, Loos RJF, Pereira AC, Province M, Psaty BM, Rotimi C, Zhu X, Amin N, Cupples LA, Fornage M, Fox EF, Guo X, Gauderman WJ, Rice K, Kooperberg C, Munroe PB, Liu CT, Morrison AC, Rao DC, van Heemst D, Redline S
    (    A1 Refereed original research article in a scientific journal)


  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity  (2019)  
    • Nature Communications
     Kilpeläinen T.O., Bentley A.R., Noordam R., Sung Y.J., Schwander K., Winkler T.W., Jakupović H., Chasman D.I., Manning A., Ntalla I., Aschard H., Brown M.R., de las Fuentes L., Franceschini N., Guo X., Vojinovic D., Aslibekyan S., Feitosa M.F., Kho M., Musani S.K., Richard M., Wang H., Wang Z., Bartz T.M., Bielak L.F., Campbell A., Dorajoo R., Fisher V., Hartwig F.P., Horimoto A.R.V.R., Li C., Lohman K.K., Marten J., Sim X., Smith A.V., Tajuddin S.M., Alver M., Amini M., Boissel M., Chai J.F., Chen X., Divers J., Evangelou E., Gao C., Graff M., Harris S.E., He M., Hsu F.-C., Jackson A.U., Zhao J.H., Kraja A.T., Kühnel B., Laguzzi F., Lyytikäinen L.-P., Nolte I.M., Rauramaa R., Riaz M., Robino A., Rueedi R., Stringham H.M., Takeuchi F., van der Most P.J., Varga T.V., Verweij N., Ware E.B., Wen W., Li X., Yanek L.R., Amin N., Arnett D.K., Boerwinkle E., Brumat M., Cade B., Canouil M., Chen Y.-D.I., Concas M.P., Connell J., de Mutsert R., de Silva H.J., de Vries P.S., Demirkan A., Ding J., Eaton C.B., Faul J.D., Friedlander Y., Gabriel K.P., Ghanbari M., Giulianini F., Gu C.C., Gu D., Harris T.B., He J., Heikkinen S., Heng C.-K., Hunt S.C., Ikram M.A., Jonas J.B., Koh W.-P., Komulainen P., Krieger J.E., Kritchevsky S.B., Kutalik Z., Kuusisto J., Langefeld C.D., Langenberg C., Launer L.J., Leander K., Lemaitre R.N., Lewis C.E., Liang J., Alizadeh B.Z., Boezen H.M., Franke L., Navis G., Rots M., Swertz M., Wolffenbuttel B.H.R., Wijmenga C., Liu J., Mägi R., Manichaikul A., Meitinger T., Metspalu A., Milaneschi Y., Mohlke K.L., Mosley T.H., Jr., Murray A.D., Nalls M.A., Nang E.-E.K., Nelson C.P., Nona S., Norris J.M., Nwuba C.V., O’Connell J., Palmer N.D., Papanicolau G.J., Pazoki R., Pedersen N.L., Peters A., Peyser P.A., Polasek O., Porteous D.J., Poveda A., Raitakari O.T., Rich S.S., Risch N., Robinson J.G., Rose L.M., Rudan I., Schreiner P.J., Scott R.A., Sidney S.S., Sims M., Smith J.A., Snieder H., Sofer T., Starr J.M., Sternfeld B., Strauch K., Tang H., Taylor K.D., Tsai M.Y., Tuomilehto J., Uitterlinden A.G., van der Ende M.Y., van Heemst D., Voortman T., Waldenberger M., Wennberg P., Wilson G., Xiang Y.-B., Yao J., Yu C., Yuan J.-M., Zhao W., Zonderman A.B., Becker D.M., Boehnke M., Bowden D.W., de Faire U., Deary I.J., Elliott P., Esko T., Freedman B.I., Froguel P., Gasparini P., Gieger C., Kato N., Laakso M., Lakka T.A., Lehtimäki T., Magnusson P.K.E., Oldehinkel A.J., Penninx B.W.J.H., Samani N.J., Shu X.-O., van der Harst P., Van Vliet-Ostaptchouk J.V., Vollenweider P., Wagenknecht L.E., Wang Y.X., Wareham N.J., Weir D.R., Wu T., Zheng W., Zhu X., Evans M.K., Franks P.W., Gudnason V., Hayward C., Horta B.L., Kelly T.N., Liu Y., North K.E., Pereira A.C., Ridker P.M., Tai E.S., van Dam R.M., Fox E.R., Kardia S.L.R., Liu C.-T., Mook-Kanamori D.O., Province M.A., Redline S., van Duijn C.M., Rotter J.I., Kooperberg C.B., Gauderman W.J., Psaty B.M., Rice K., Munroe P.B., Fornage M., Cupples L.A., Rotimi C.N., Morrison A.C., Rao D.C., Loos R.J.F.; Lifelines Cohort Study
    (    A1 Refereed original research article in a scientific journal)


  • Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy  (2019)  
    • American Journal of Human Genetics
     Nath AP, Ritchie SC, Grinberg NF, Tang HH, Huang QQ, Teo SM, Ahola-Olli AV, Würtz P, Havulinna AS, Santalahti K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salmi M, Wallace C, Raitakari OT, Salomaa V, Abraham G, Kettunen J, Inouye M
    (    A1 Refereed original research article in a scientific journal)


  • Natural History of Atherosclerosis and Abdominal Aortic Intima-Media Thickness: Rationale, Evidence, and Best Practice for Detection of Atherosclerosis in the Young  (2019)  
    • Journal of Clinical Medicine
     Michael R. Skilton, David S. Celermajer, Erich Cosmi, Fatima Crispi, Samuel S. Gidding, Olli T. Raitakari, Elaine M. Urbina
    (    A2 Refereed review article in a scientific journal )


  • New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders  (2019)  
    • Nature Human Behaviour
     Evangelos Evangelou, He Gao, Congying Chu, Georgios Ntritsos, Paul Blakeley, Andrew R. Butts, Raha Pazoki, Hideaki Suzuki, Fotios Koskeridis, Andrianos M. Yiorkas, Ibrahim Karaman, Joshua Elliott, Qiang Luo, Stefanie Aeschbacher, Traci M. Bartz, Sebastian E. Baumeister, Peter S. Braund, Michael R. Brown, Jennifer A. Brody, Toni-Kim Clarke, Niki Dimou, Jessica D. Faul, Georg Homuth, Anne U. Jackson, Katherine A. Kentistou, Peter K. Joshi, Rozenn N. Lemaitre, Penelope A. Lind, Leo-Pekka Lyytikäinen, Massimo Mangino, Yuri Milaneschi, Christopher P. Nelson, Ilja M. Nolte, Mia-Maria Perälä, Ozren Polasek, David Porteous, Scott M. Ratliff, Jennifer A. Smith, Alena Stančáková, Alexander Teumer, Samuli Tuominen, Sébastien Thériault, Jagadish Vangipurapu, John B. Whitfield, Alexis Wood, Jie Yao, Bing Yu, Wei Zhao, Dan E. Arking, Juha Auvinen, Chunyu Liu, Minna Männikkö, Lorenz Risch, Jerome I. Rotter, Harold Snieder, Juha Veijola, Alexandra I. Blakemore, Michael Boehnke, Harry Campbell, David Conen, Johan G. Eriksson, Hans J. Grabe, Xiuqing Guo, Pim van der Harst, Catharina A. Hartman, Caroline Hayward, Andrew C. Heath, Marjo-Riitta Jarvelin, Mika Kähönen, Sharon L. R. Kardia, Michael Kühne, Johanna Kuusisto, Markku Laakso, Jari Lahti, Terho Lehtimäki, Andrew M. McIntosh, Karen L. Mohlke, Alanna C. Morrison, Nicholas G. Martin, Albertine J. Oldehinkel, Brenda W. J. H. Penninx, Bruce M. Psaty, Olli T. Raitakari, Igor Rudan, Nilesh J. Samani, Laura J. Scott, Tim D. Spector, Niek Verweij, David R. Weir, James F. Wilson, Daniel Levy, Ioanna Tzoulaki, Jimmy D. Bell, Paul M. Matthews, Adrian Rothenfluh, Sylvane Desrivières, Gunter Schumann, Paul Elliott
    (    A1 Refereed original research article in a scientific journal)


  • New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults  (2019)  
    • Journal of Lipid Research
     Karjalainen JP, Mononen N, Hutri-Kähönen N, Lehtimäki M, Hilvo M, Kauhanen D, Juonala M, Viikari J, Kähönen M, Raitakari O, Laaksonen R, Lehtimäki T
    (    A1 Refereed original research article in a scientific journal)


  • New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries  (2019)  
    • Nature Genetics
     Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li XN, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimaki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bosse Y, Brandsma CA, Chen ZM, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li LM, Lin K, Lind L, Locantore N, Luan JA, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao DD, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Artigas MS, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Verges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kahonenn M, Polasek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV, Tobin MD, Wain LV, Strachan DP, Hall IP
    (    A1 Refereed original research article in a scientific journal)


  • Parent-Child-Relationship Quality Predicts Offspring Dispositional Compassion in Adulthood: A Prospective Follow-Up Study Over Three Decades  (2019)  
    • Developmental Psychology
     Hintsanen Mirka, Gluschkoff Kia, Dobewall Henrik, Cloninger C. Robert, Keltner Dacher, Saarinen Aino, Wesolowska Karolina, Volanen Salla-Maarit, Raitakari Olli T., Pulkki-Råback Laura
    (    A1 Refereed original research article in a scientific journal)


  • Personality traits and perceptions of organisational justice  (2019)  
    • International Journal of Psychology
     Törnroos Maria, Elovainio Marko, Hintsa Taina, Hintsanen Mirka, Pulkki-Råback Laura, Jokela Markus, Lehtimäki Terho, Raitakari Olli T., Keltikangas-Järvinen Liisa
    (    A1 Refereed original research article in a scientific journal)


  • Physical activity from childhood to adulthood and cognitive performance in midlife  (2019)  
    • Medicine and Science in Sports and Exercise
     Hakala J.O., Rovio S.P., Pahkala K., Nevalainen J., Juonala M., Hutri-Kähönen N., Heinonen O.J., Hirvensalo M., Telama R., Viikari J.S., Tammelin T.H., Raitakari O.T.
    (    A1 Refereed original research article in a scientific journal)


  • Physical Activity, Sleep, and Symptoms of Depression in Adults-Testing for Mediation  (2019)  
    • Medicine and Science in Sports and Exercise
     Kaisa Kaseva, Henrik Dobewall, Xiaolin Yang, Laura Pulkki-Råback, Jari Lipsanen, Taina Hintsa, Mirka Hintsanen, Sampsa Puttonen, Mirja Hirvensalo, Marko Elovainio, Olli Raitakari, Tuija Tammelin
    (    A1 Refereed original research article in a scientific journal)


  • Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals  (2019)  
    • Molecular Nutrition and Food Research
     Murphy AM, Smith CE, Murphy LM, Follis JL, Tanaka T, Richardson K, Noordam R, Lemaitre RN, Kahonen M, Dupuis J, Voortman T, Marouli E, Mook-Kanamori DO, Raitakari OT, Hong J, Dehghan A, Dedoussis G, de Mutsert R, Lehtimaki T, Liu CT, Rivadeneira F, Deloukas P, Mikkila V, Meigs JB, Uitterlinden A, Lkram MA, Franco OH, Hughes M, O'Gaorajose P, Ordovas JM, Roche HM, Roche HM
    (    A1 Refereed original research article in a scientific journal)


  • Predicting overweight and obesity in young adulthood from childhood body-mass index: comparison of cutoffs derived from longitudinal and cross-sectional data  (2019)  
    • The Lancet Child & Adolescent Health
     Kartiosuo N, Ramakrishnan R, Lemeshow S, Juonala M, Burns TL, Woo JG, Jr DR, Daniels SR, Venn A, Steinberger J, Urbina EM, Bazzano L, Sabin MA, Hu T, Prineas RJ, Sinaiko AR, Pahkala K, Raitakari O, Dwyer T, Dwyer T
    (    A1 Refereed original research article in a scientific journal)


  • Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution  (2019)  
    • Nature Genetics
     Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu YC, Turcot V, Auer PL, Fine RS, Guo XQ, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, Locke AE, Medina-Gomez C, Esko T, Vedantam S, Giri A, Lo KS, Alfred T, Mudgal P, Ng MCY, Heard-Costa NL, Feitosa MF, Manning AK, Willems SM, Sivapalaratnam S, Abecasis G, Alam DS, Allison M, Amouyel P, Arzumanyanm Z, Balkau B, Bastarache L, Bergmann S, Bielak LF, Blueher M, Boehnke M, Boeing H, Boerwinkle E, Boger CA, Bork-Jensen J, Bottinger EP, Bowden DW, Brandslund I, Broer L, Burt AA, Butterworth AS, Caulfield M, Cesana G, Chambers JC, Chasman DI, Chen YDI, Chowdhury R, Christensen C, Chu A, Collins FS, Cook JP, Cox AJ, Crosslin DS, Danesh J, de Bakker PIW, de Denus S, de Mutsert R, Dedoussis G, Demerath EW, Dennis JG, Denny JC, Di Angelantonio E, Dorr M, Drenos F, Dube MP, Dunning AM, Easton DF, Elliott P, Evangelou E, Farmaki AE, Feng S, Ferrannini E, Ferrieres J, Florez JC, Fornage M, Fox CS, Franks PW, Friedrich N, Gan W, Gandin I, Gasparini P, Giedraitis V, Girotto G, Gorski M, Grallert H, Grarup N, Groves ML, Gustafsson S, Haessler J, Hansen T, Hattersley AT, Hayward C, Heid IM, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Hung YJ, Hveem K, Ikram MA, Ingelsson E, Jackson AU, Jarvik GP, Jia YC, Jorgensen T, Jousilahti P, Justesen JM, Kahali B, Karaleftheri M, Kardia SLR, Karpe F, Kee F, Kitajima H, Komulainen P, Kooner JS, Kovacs P, Kramer BK, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, La Nge LA, Langenberg C, Larson EB, Lee NR, Lee WJ, Lehtimaki T, Lewis CE, Li HX, Li J, RuifangLi-Gao, Lin LA, Lin X, Lind L, Lindstrom J, Linneberg A, Liu CT, Liu DJJ, Luan J, Lyytikainen LP, MacGregor S, Magi R, Mannisto S, Marenne G, Marten J, Mascal NGD, McCarthy MI, Meidtner K, Mihailov E, Moilanen L, Moitry M, Mook-Kanamori DO, Morgan A, Morris AP, Muller-Nurasyid M, Munroe PB, Narisu N, Nelson CP, Neville M, Ntalla I, Owen KR, Pedersen O, Peloso GM, Pennell CE, Perola M, James A, Perry JRB, Pers TH, Ewing A, Polasek O, Rasheed A, Raulerson CK, Rauramaa R, Reilly DF, Reiner AP, Ridker PM, Rivas MA, Robertson NR, Robino A, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe M, Sim XL, Slater AJ, Small KS, Smith BH, Smith JA, Southam L, Spector TD, Speliotes EK, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swart KMA, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tonjes A, Torres M, Tsafantakis E, Tuomilehto J, Uitterlinden AG, Uusitupa M, van Duijn CM, Vanhala M, Varma R, Vermeulen SH, Vestergaard H, Vitart V, Vogt TF, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang FJ, Wang CA, Wang S, Wareham NIJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Wood AR, Wu Y, Yaghootkar H, Yao J, Verges-Armstrong LM, Young R, Zeggini E, Zhan XW, Zhang WH, Zhao JH, Zhao W, Zheng H, Zhou W, Zillikens MC, Rivadeneira F, Borecki IB, Pospisilik JA, Deloukas P, Frayling TM, Lettre G, Mohlke KL, Rotter JI, Kutalik Z, Hirschhorn JN, Cupples LA, Loos RJF, North KE, Lindgren CM, O'Connell JR, Raitakari OT, Danesh J, Surendran P, Young R, Liu CT, Borecki IB, Cupples LA, North KE, Boerwinkle E, Fornage M, Wilson JG, Lange LA, Ikram MA, Uitterlinden AG, Justice AE, Highland HM, Young KL, Graff M, Grove ML, Heard-Costa NL, Zillikens MC, Danesh J, Surendran P, Young R, Cook JP, Warren HR, Yaghootkar H, Masca NGD, Mihailov E, Marten J, Stirrups KE, Neville M, Robertson NR, Zhang WH, Evangelou E, Nelson CP, Luan JA, Scott RA, Farmaki AE, Polasek O, Rudan I, Franks PW, Spector TD, Wareham NJ, Esko T, Ingelsson E, De Bakker PI, Chambers JC, Kooner JS, Karpe F, Tuomilehto J, Morris AP, Hveem K, Willer CJ, Salomaa V, McCarthy MI, Elliott P, Zeggini E, Hayward C, Caulfield MJ, Mahajan A, Morris AP, Samani NJ, Lindgren CM, Munroe PB, Willer CJ, Manning AK, Sim XL, Locke AE, Jackson AU, Stringham HM, Boehnke M, Tuomilehto J, Collins FS, Mohlke KL, Abecasis G, Muller-Nurasyid M, Rivas MA, Mahajan A, Small KS, Lindgren CM, Robertson NR, Morris AP, Hattersley AT, Spector TD, Frayling TM, McCarthy MI, Willems SM, Manning AK, Frayling TM, Florez JC, Chambers JC, Kooner JS, Zhang WH, McCarthy MI, Lindgren CM, Mahajan A, Morris AP, Rivas MA, Willems SM, Laakso M, Boehnke M, Sim XL, Locke AE, Abecasis G, Wilson JG, Highland HM, Bowden DW, Zeggini E, Boehnke M, Florez JC, McCarthy MI, McCarthy MI, Florez JC
    (    A1 Refereed original research article in a scientific journal)


  • Relation of Blood Pressure in Childhood to Self-Reported Hypertension in Adulthood: The International Childhood Cardiovascular Cohort Consortium  (2019)  
    • Hypertension
     Urbina EM, Khoury PR, Bazzano L, Burns TL, Daniels S, Dwyer T, Hu T, Jacobs DR, Juonala M, Prineas R, Raitakari O, Steinberger J, Venn A, Woo JG, Sinaiko A
    (    A1 Refereed original research article in a scientific journal)



Last updated on 2023-12-07 at 12:01