MD, PhD, Professor of Biomedicine Sari Mäkelä - UTU Research Portal

Sari Mäkelä
MD, PhD, Professor of Biomedicine

- Professor,
Institute of Biomedicine (Faculty of Medicine)

sarmak@utu.fi

+358 29 450 2536

+358 40 514 3714

Kiinamyllynkatu 10

Turku

: https://orcid.org/0000-0002-8698-4076

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Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products (2015)
- Natural Product Reports
Kibble M, Saarinen N, Tang J, Wennerberg K, Mäkelä S, Aittokallio T
Weight gain and inflammation regulate aromatase expression in male adipose tissue, as evidenced by reporter gene activity (2015)
- Molecular and Cellular Endocrinology
Polari L., Yatkin E., Martínez Chacón M., Ahotupa M., Smeds A., Strauss L., Zhang F., Poutanen M., Saarinen N., Mäkelä S.
Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model (2014)
- American Journal of Pathology
Matias Knuuttila, Emrah Yatkin, Jenny Kallio, Saija Savolainen, Teemu D. Laajala, Tero Aittokallio, Riikka Oksala, Merja Häkkinen, Pekka Keski-Rahkonen, Seppo Auriola, Matti Poutanen, Sari Mäkelä
Castration induces upregulation of intratumoral androgen biosynthesis and androgen receptor expression in orthotopic VCaP human prostate cancer xenograft model (2014)
- Cancer Research
Matias Knuuttila, Emrah Yatkin, Jenny Kallio, Saija Savolainen, Teemu Daniel Laajala, Tero Aittokallio, Riikka Oksala, Merja Häkkinen, Pekka Keski-Rahkonen, Seppo Auriola, Matti Poutanen, Sari Mäkelä
Deficiency of ERβ and prostate tumorigenesis in FGF8b transgenic mice (2014)
- Endocrine-Related Cancer
Teresa Elo, Lan Yu, Eeva Valve, Sari Mäkelä, Pirkko Härkönen
Lihavuuden vaikutus estrogeenisignalointiin ja rintasyöpäriskiin (2014)
- Lääkärilehti
Saarinen Niina, Mäkelä Sari
Novel Lignan and Stilbenoid Mixture Shows Anticarcinogenic Efficacy in Preclinical PC-3M-luc2 Prostate Cancer Model (2014)
- PLoS ONE
Yatkin E, Polari L, Laajala TD, Smeds A, Eckerman C, Holmbom B, Saarinen N, Aittokallio T, Mäkelä S.
A reporter mouse model reveals that human CYP19A1 (aromatase) gene expression is induced in breast cancer xenograft stroma and surrounding mammary gland by the cancer cells in vivo. (2013)
- Cancer Research
Järvensivu P, Strauss L, Mäkelä S, Poutanen M, Saarinen N
Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens (2013)
- FASEB Journal
Strauss L, Rantakari P, Sjogren K, Salminen A, Lauren E, Kallio J, Damdimopoulou P, Bostrom M, Bostrom PJ, Pakarinen P, Zhang FP, Kujala P, Ohlsson C, Makela S, Poutanen M
Cadmium-Induced Effects on Cellular Signaling Pathways in the Liver of Transgenic Estrogen Reporter Mice (2012)
- Toxicological Sciences
Ali I, Damdimopoulou P, Stenius U, Adamsson A, Makela SI, Akesson A, Berglund M, Hakansson H, Halldin K