Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 |
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
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- Synthesis of Aminoglycoside-3 '-Conjugates of 2 '-O-Methyl Oligoribonucleotides and Their Invasion to a F-19 labeled HIV-1 TAR Model (2011)
- Bioconjugate Chemistry
- THE Zn2+ COMPLEX OF 1,4,7,10-TETRAAZACYCLODODECANE AS AN ARTIFICIAL NUCLEOBASE (2011)
- Nucleosides, Nucleotides and Nucleic Acids
- Characterization of RNA Invasion by F-19 NMR Spectroscopy (2010)
- Journal of the American Chemical Society
- Solid-Supported Synthesis and Click Conjugation of 4 '-C-Alkyne Functionalized Oligodeoxyribonucleotides (2010)
- Bioconjugate Chemistry
- Synthesis of 4’-C-N,N-Bis[pentyn-4-yl)aminomethyl]thymidine and 4’-C-[N-Methyl-N-(pentyn-4-yl)aminomethyl]thymidine Monomers And Their Use in Conjugation of Oligonucleotides via Click Chemistry on a Solid Support (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Kiviniemi A, Virta P, Lönnberg H
- Synthesis of Oligonucleotide Glycoconjugates Using Sequential Click and Oximation Ligations (2010)
- Bioconjugate Chemistry
- 4-Oxoheptanedioic acid: an orthogonal linker for solid-phase synthesis of base-sensitive oligonucleotides (2008)
- Tetrahedron Letters
- 4-oxoheptanedioic acid linker in the synthesis of base-sensitive oligonucleotides (2008)
- Collection Symposium Series
- Base and sequence selective cleavage of RNA phosphodiester bonds by Zn(II) azacrown chelates (2008)
- Collection Symposium Series
- Di(azacrown) conjugates of 2 '-O-methyl oligoribonucleotides as sequence-selective artificial ribonucleases (2008)
- Collection Symposium Series
- Synthesis and Cellular Uptake of Fluorescently Labeled Multivalent Hyaluronan Disaccharide Conjugates of Oligonucleotide Phosphorothioates (2008)
- Bioconjugate Chemistry
- Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotides (2008)
- Collection Symposium Series
- Utilization of intrachain 4 '-C-azidomethylthymidine for preparation of oligodeoxyribonucleotide conjugates by click chemistry in solution and on a solid support (2008)
- Bioconjugate Chemistry
- Di(azacrown) conjugates of 2 '-O-Methyl Oligoribonucleotides as sequence-selective artificial ribonucleases (2007)
- Bioconjugate Chemistry
- Orthogonally protected cyclo-beta-tetrapeptides as solid-supported scaffolds for the synthesis of glycoclusters (2006)
- Journal of Organic Chemistry
- Synthesis of bicyclic peptides (2006)
- Current Organic Synthesis
- 2,2-Bis(ethoxycarbonyl)- and 2-(alkylaminocarbonyl)-2-cyano-substituted 3-(pivaloyloxy)propyl groups as biodegradable phosphate protections of oligonucleotides (2005)
- Bioconjugate Chemistry
- On-support oximation: A convenient method for solid-supported conjugation of oligonucleotides (2005)
- Collection Symposium Series
- Pentaerythrityltetramine scaffolds for solid-phase combinatorial chemistry (2004)
- Journal of Organic Chemistry
- Preparation of azacrown-functionalized 2 '-O-methyl oligoribonucleotides, potential artificial RNases (2004)
- Bioconjugate Chemistry
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