Professor Pasi Virta - UTU Research Portal

Pasi Virta
Professor

- Professor,
Pharmaseutical Chemistry (Department of Chemistry)

pamavi@utu.fi

+358 29 450 3209

+358 50 328 5719

: https://orcid.org/https://orcid.org/0000-0002-6218-2212

Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation

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Site-Specific Linking of an Oligonucleotide to Mono- and Bivalent Recombinant Antibodies with SpyCatcher-SpyTag System for Immuno-PCR (2020)
- ACS Omega
Anastasiia Kushnarova-Vakal, Antti Äärelä, Tuomas Huovinen, Pasi Virta, Urpo Lamminmäki
3-Fluoro-2-mercuri-6-methylaniline Nucleotide as a High-Affinity Nucleobase-Specific Hybridization Probe (2019)
- Bioconjugate Chemistry
Aro-Heinilä A, Lönnberg T, Virta P
Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin (2019)
- Scientific Reports
Rosenqvist P, Palmu K, Prajapati RK, Yamada K, Niemi J, Belogurov GA, Metsa-Ketela M, Virta P
gamma-(S)-Guanidinylmethyl-Modified Triplex-Forming Peptide Nucleic Acids Increase Hoogsteen-Face Affinity for a MicroRNA and Enhance Cellular Uptake (2019)
- ChemBioChemNucleic Acids Research
Tähtinen V, Verhassel A, Tuomela J, Virta P
Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography (2019)
- Molecular PharmaceuticsMolecules
Jussi Mäkilä, Anu Kiviniemi, Tiina Saanijoki, Heidi Liljenbäck, Meeri Käkelä, Satish Jadhav, Päivi Poijärvi-Virta, Harri Lönnberg, Tiina Laitala-Leinonen, Pasi Virta, Anne Roivainen
Oxazinomycin arrests RNA polymerase at the polythymidine sequences (2019)
Prajapati R.K., Rosenqvist P., Palmu K., Mäkinen J.J., Malinen A.M., Virta P., Metsä-Ketelä M., Belogurov G.A.
Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a F-18-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies (2019)
- European Journal of Organic Chemistry
Sajal K. Maity, Cheng-Bin Yim, Satish Jadhav, Alejandra Verhassel, Johanna Tuomela, Olof Solin, Tove J. Grönroos, Pasi Virta
Synthesis of Glycosidic (beta-1 ''-> 6,3 ' and 4 ') Site Isomers of Neomycin B and Their Effect on RNA and DNA Triplex Stability (2019)
Granqvist Lotta, Tähtinen Ville, Virta Pasi
(2018)
- Organic LettersEuropean Journal of Organic Chemistry
Tommi Österlund, Heidi Korhonen, Pasi Virta
Synthesis and Applicability of Base-Discriminating DNA-Triplex-Forming 19F NMR Probes (2018)
Bhuma N., Tähtinen V., Virta P.