Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6218-2212 |
Areas of expertise
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Publications 
5 of 6
- Characterization of RNA Invasion by F-19 NMR Spectroscopy (2010)
- Journal of the American Chemical Society
(A1 Refereed original research article in a scientific journal) - Solid-Supported Synthesis and Click Conjugation of 4 '-C-Alkyne Functionalized Oligodeoxyribonucleotides (2010)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of 4’-C-N,N-Bis[pentyn-4-yl)aminomethyl]thymidine and 4’-C-[N-Methyl-N-(pentyn-4-yl)aminomethyl]thymidine Monomers And Their Use in Conjugation of Oligonucleotides via Click Chemistry on a Solid Support (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Kiviniemi A, Virta P, Lönnberg H
(B3 Non-refereed article in a conference publication) - Synthesis of Oligonucleotide Glycoconjugates Using Sequential Click and Oximation Ligations (2010)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - 4-Oxoheptanedioic acid: an orthogonal linker for solid-phase synthesis of base-sensitive oligonucleotides (2008)
- Tetrahedron Letters
(A1 Refereed original research article in a scientific journal) - 4-oxoheptanedioic acid linker in the synthesis of base-sensitive oligonucleotides (2008)
- Collection Symposium Series
(B1 Non-refereed article in a scientific journal) - Base and sequence selective cleavage of RNA phosphodiester bonds by Zn(II) azacrown chelates (2008)
- Collection Symposium Series
(B1 Non-refereed article in a scientific journal) - Di(azacrown) conjugates of 2 '-O-methyl oligoribonucleotides as sequence-selective artificial ribonucleases (2008)
- Collection Symposium Series
(B1 Non-refereed article in a scientific journal) - Synthesis and Cellular Uptake of Fluorescently Labeled Multivalent Hyaluronan Disaccharide Conjugates of Oligonucleotide Phosphorothioates (2008)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotides (2008)
- Collection Symposium Series
(B1 Non-refereed article in a scientific journal) - Utilization of intrachain 4 '-C-azidomethylthymidine for preparation of oligodeoxyribonucleotide conjugates by click chemistry in solution and on a solid support (2008)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Di(azacrown) conjugates of 2 '-O-Methyl Oligoribonucleotides as sequence-selective artificial ribonucleases (2007)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Orthogonally protected cyclo-beta-tetrapeptides as solid-supported scaffolds for the synthesis of glycoclusters (2006)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of bicyclic peptides (2006)
- Current Organic Synthesis
(A2 Refereed review article in a scientific journal ) - 2,2-Bis(ethoxycarbonyl)- and 2-(alkylaminocarbonyl)-2-cyano-substituted 3-(pivaloyloxy)propyl groups as biodegradable phosphate protections of oligonucleotides (2005)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - On-support oximation: A convenient method for solid-supported conjugation of oligonucleotides (2005)
- Collection Symposium Series
(B1 Non-refereed article in a scientific journal) - Pentaerythrityltetramine scaffolds for solid-phase combinatorial chemistry (2004)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Preparation of azacrown-functionalized 2 '-O-methyl oligoribonucleotides, potential artificial RNases (2004)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Solid-phase synthesis of multiantennary oligonucleotide glycoconjugates utilizing on-support oximation (2004)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Solid-supported synthesis of bicyclic peptides containing three parallel peptide chains (2003)
- European Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal)
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