Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6218-2212 |
Areas of expertise
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Publications 
3 of 5
- Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a F-18-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies (2019)
- European Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of Glycosidic (beta-1 ''-> 6,3 ' and 4 ') Site Isomers of Neomycin B and Their Effect on RNA and DNA Triplex Stability (2019)
- Molecules
(A1 Refereed original research article in a scientific journal) - DNA-Templated N(Me)-Alkoxyamine Glycosylation (2018)
- Organic Letters
(A1 Refereed original research article in a scientific journal) - Synthesis and Applicability of Base-Discriminating DNA-Triplex-Forming 19F NMR Probes (2018)
- European Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of Azide-Modified Chondroitin Sulfate Precursors: Substrates for "Click"-Conjugation with Fluorescent Labels and Oligonucleotides (2018)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics (2017)
- ACS Chemical Biology
(A1 Refereed original research article in a scientific journal) - DNA barcoding reveals widespread occurrence of Leptidea juvernica (Lepidoptera: Pieridae) in southern Finland (2017)
- Entomologisk tidskrift
(A1 Refereed original research article in a scientific journal) - F-19 NMR Spectroscopic Analysis of the Binding Modes in Triple-Helical Peptide Nucleic Acid (PNA)/MicroRNA Complexes (2017)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - Synthesis of Aminoglycoside-2 '-O-Methyl Oligoribonucleotide Fusions (2017)
- Molecules
(A1 Refereed original research article in a scientific journal) - Zinc Ion-Dependent Peptide Nucleic Acid-Based Artificial Enzyme that Cleaves RNABulge Size and Sequence Dependence (2017)
- Molecules
(A1 Refereed original research article in a scientific journal) - Characterization of G-quadruplex/hairpin transitions of RNA by 19F NMR spectroscopy (2016)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - In-Vivo Bone-Targeting of Bis(phosphonate)-Conjugated Double Helical RNA Monitored by Positron Emission Tomography (2016)
- Molecular Pharmaceutics
(A1 Refereed original research article in a scientific journal) - Solid-supported porphyrins useful for the synthesis of conjugates with oligomeric biomolecules (2016)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis and In Vivo PET Imaging of Hyaluronan Conjugates of Oligonucleotides (2016)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of protected 2´-O-deoxyribonucleotides on a precipitative soluble support: a useful procedure for the preparation of trimer phosphoramidites (2016)
- RSC Advances
(A1 Refereed original research article in a scientific journal) - 2 '-O-[(4-CF3-triazol-1-yl)methyl] Uridine - A Sensitive F-19 NMR Sensor for the Detection of RNA Secondary Structures (2015)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Assembly of short oligoribonucleotides from commercially available building blocks on a tetrapodal soluble support (2015)
- Current Organic Synthesis
(A1 Refereed original research article in a scientific journal) - Preparation of a disulfide-linked precipitative soluble support for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3´-(2-chlorophenylphosphate) building blocks (2015)
- Beilstein Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of C-5, C-2 ' and C-4 '-neomycin-conjugated triplex forming oligonucleotides and their affinity to DNA-duplexes (2015)
- Bioorganic and Medicinal Chemistry
(A1 Refereed original research article in a scientific journal) - 4 '-C-[(4-Trifluoromethyl-1H-1,2,3-triazol-1-yl)methyl]thymidine as a Sensitive F-19 NMR Sensor for the Detection of Oligonucleotide Secondary Structures (2014)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal)
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