Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6218-2212 |
Areas of expertise
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Publications 
2 of 5
- Synthesis of an Azide- and Tetrazine-Functionalized [60]Fullerene and Its Controlled Decoration with Biomolecules (2022)
- ACS Omega
(A1 Refereed original research article in a scientific journal) - The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner (2022)
- Nucleic Acids Research
(A1 Refereed original research article in a scientific journal) - The role of the maleimide ring system on the structure-activity relationship of showdomycin (2022)
- European Journal of Medicinal Chemistry
(A1 Refereed original research article in a scientific journal) - Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core (2021)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Covalently Mercurated Molecular Beacon for Discriminating the Canonical Nucleobases (2021)
- ChemBioChem
(A1 Refereed original research article in a scientific journal) - Drug-to-Antibody Ratio Estimation via Proteoform Peak Integration in the Analysis of Antibody-Oligonucleotide Conjugates with Orbitrap Fourier Transform Mass Spectrometry (2021)
- Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - Expanding the Scope of the Cleavable N-(Methoxy)oxazolidine Linker for the Synthesis of Oligonucleotide Conjugates (2021)
- Molecules
(A1 Refereed original research article in a scientific journal) - More versatile synthesis of oligonucleotides (2021)
- Science
(B1 Non-refereed article in a scientific journal) - Stability of the Phosphotriester PDE6D Inhibitors (2021)
- ChemistrySelect
(A1 Refereed original research article in a scientific journal) - Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support (2021)
- RSC Advances
(A1 Refereed original research article in a scientific journal) - The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases (2021)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Conjugation of Oligonucleotides to Peptide Aldehydes via a pH-Responsive N-Methoxyoxazolidine Linker (2020)
- Organic Letters
(A1 Refereed original research article in a scientific journal) - Immobilized Carbohydrates for Preparation of 3'-Glycoconjugated Oligonucleotides (2020)
- Current Protocols in Nucleic Acid Chemistry
(A1 Refereed original research article in a scientific journal) - PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity (2020)
- ACS Omega
(A1 Refereed original research article in a scientific journal) - Site-Specific Linking of an Oligonucleotide to Mono- and Bivalent Recombinant Antibodies with SpyCatcher-SpyTag System for Immuno-PCR (2020)
- ACS Omega
(A1 Refereed original research article in a scientific journal) - 3-Fluoro-2-mercuri-6-methylaniline Nucleotide as a High-Affinity Nucleobase-Specific Hybridization Probe (2019)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin (2019)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - gamma-(S)-Guanidinylmethyl-Modified Triplex-Forming Peptide Nucleic Acids Increase Hoogsteen-Face Affinity for a MicroRNA and Enhance Cellular Uptake (2019)
- ChemBioChem
(A1 Refereed original research article in a scientific journal) - Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography (2019)
- Molecular Pharmaceutics
(A1 Refereed original research article in a scientific journal) - Oxazinomycin arrests RNA polymerase at the polythymidine sequences (2019)
- Nucleic Acids Research
(A1 Refereed original research article in a scientific journal)
UTU Research Portal