Sakari Hietanen

- Docent,
Faculty of Medicine (University of Turku)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

sakari.hietanen@utu.fi

2 of 4

Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial (2023)
- JCO Precision Oncology
Pujade-Lauraine E, Brown J, Barnicle A, Wessen J, Lao-Sirieix P, Criscione SW, du Bois A, Lorusso D, Romero I, Petru E, Yoshida H, Vergote I, Colombo N, Hietanen S, Provansal M, Schmalfeldt B, Pignata S, Lorente CM, Berton D, Runnebaum IB, Ray-Coquard I
Multi-omics characterization of chemo-refractory high-grade serous cancer (2023)
- International Journal of Gynecological Cancer
Muranen, Taru A.; Afenteva, Daria; Rajavuori, Anna; Jamalzadeh, Sanaz; Zhang, Kaiyang; Ariotta, Valeria; Isoviita, Veli-Matti; Lahtinen, Alexandra; Lavikka, Kari; Lehtonen, Oskari; Li, Yilin; Marchi, Giovanni; Oikkonen, Jaana; Salloum, Shams; Huhtinen, Kaisa; Hietanen, Sakari; Virtanen, Anni; Hynninen, Johanna; Hautaniemi, Sampsa
Normalized LST Is an Efficient Biomarker for Homologous Recombination Deficiency and Olaparib Response in Ovarian Carcinoma (2023)
- JCO Precision Oncology
Christinat Yann, Ho Liza, Clément Sophie, Genestie Catherine, Sehouli Jalid, Cinieri Saverio, Gonzalez Martin Antonio, Denison Ursula, Fujiwara Keiichi, Vergote Ignace, Tognon Germana, Hietanen Sakari, Ray-Coquard Isabelle, Pujade-Lauraine Eric, McKee Thomas A
Overall survival and patient-reported outcome results from the placebo-controlled randomized phase III IMagyn050/GOG 3015/ ENGOT-OV39 trial of atezolizumab for newly diagnosed stage III/IV ovarian cancer (2023)
- Gynecologic Oncology
Pignata S, Bookman M, Sehouli J, Miller A, Penson RT, Taskiran C, Anderson C, Hietanen S, Myers T, Madry R, Willmott L, Lortholary A, Thomes-Pepin J, Aghajanian C, Mccourt C, Stuckey A, Wu XH, Nishio S, Copeland LJ, He YT, Molinero L, Patel S, Lin YG, Khor VK, Moore KN
Cisplatin overcomes radiotherapy resistance in OCT4-expressing head and neck squamous cell carcinoma (2022)
- Oral Oncology
Routila Johannes, Qiao Xi, Weltner Jere, Rantala Juha K, Carpén Timo, Hagström Jaana, Mäkitie Antti, Leivo Ilmo, Ruuskanen Miia, Söderlund Jenni, Rintala Marjut, Hietanen Sakari, Irjala Heikki, Minn Heikki, Westermarck Jukka, Ventelä Sami
Efficacy of niraparib by time of surgery and postoperative residual disease status: A post hoc analysis of patients in the PRIMA/ENGOT-OV26/GOG-3012 study (2022)
- Gynecologic Oncology
O'Cearbhaill Roisin E., Pérez-Fidalgo Jose-Alejandro, Monk Bradley J., Tusquets Ignacio, McCormick Colleen, Fuentes Jose, Moore Richard G., Vulsteke Christof, Shahin Mark S., Forget Frédéric, Bradley William H., Hietanen Sakari, O'Malley David M., Dørum Anne, Slomovitz Brian M., Baumann Klaus, Selle Frédéric, Calvert Paula M., Artioli Gracia, Levy Tally., Kumar Aalok, Malinowska Izabela A., Li Yong, Gupta Divya, González-Martín Antonio
Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer (2022)
- Science Advances
Zhang Kaiyang, Erkan Erdogan Pekcan, Jamalzadeh Sanaz, Dai Jun, Andersson Noora, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Oikkonen Jaana, Hynninen Johanna, Virtanen Anni, Häkkinen Antti, Hautaniemi Sampsa, Vähärautio Anna
Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer (2022)
- npj Precision Oncology
Perez-Villatoro Fernando, Oikkonen Jaana, Casado Julia, Chernenko Anastasiya, Gulhan Doga C., Tumiati Manuela, Li Yilin, Lavikka Kari, Hietanen Sakari, Hynninen Johanna, Haltia Ulla-Maija, Tyrmi Jaakko S., Laivuori Hannele, Konstantinopoulos Panagiotis A., Hautaniemi Sampsa, Kauppi Liisa, Färkkilä Anniina
QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability (2022)
- Laboratory Investigation
Jamalzadeh Sanaz, Häkkinen Antti, Andersson Noora, Huhtinen Kaisa, Laury Anna, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Carpén Olli, Virtanen Anni, Hautaniemi Sampsa
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality (2021)
- Scientific Reports
Jukonen Joonas, Moyano-Galceran Lidia, Höpfner Katrin, Pietilä Elina A, Lehtinen Laura, Huhtinen Kaisa, Gucciardo Erica, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Ojala Päivi M, Carpén Olli, Lehti Kaisa
Agile Workflow For Interactive Analysis Of Mass Cytometry Data (2021)
- Bioinformatics
Casado J, Lehtonen O, Rantanen V, Kaipio K, Pasquini L, Häkkinen A, Petrucci E, Hynninen J, Hietanen S, Carpén O, Biffoni M, Färkkilä A, Hautaniemi S
A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer (2021)
- Cancers
Salminen Liina, Braicu EIena, Lääperi Mitja, Jylhä Antti, Oksa Sinikka, Hietanen Sakari, Sehouli Jalid, Kulbe Hagen, du Bois Andras du, Mahner Sven, Harter Philipp, Carpen Oolli, Huhtinen Kaisa, Hynninen Johanna, Hilvo Mika
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021)
- Nature Communications
Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
Comorbidity of Dermal and Cardiovascular Disorders with Lichen Sclerosus: A Case-control Study (2021)
- Acta Dermato-Venereologica
Hieta Niina, Rintala Marjut, Söderlund Jenni M, Kurki Samu, Orte Katri, Hietanen Sakari
Diagnostic efficiency of whole-body 18F-FDG PET/MRI, MRI alone, and SUV and ADC values in staging of primary uterine cervical cancer (2021)
- Cancer Imaging
Steiner Aida, Narva Sara, Rinta-Kiikka Irina, Hietanen Sakari, Hynninen Johanna, Virtanen Johanna
FUNGI: Fusion Gene Integration Toolset (2021)
- Bioinformatics
Cervera Alejandra, Rausio Heidi, Kähkönen Tiia, Andersson Noora, Partel Gabriele, Rantanen Ville, Paciello Giulia, Ficarra Elisa, Hynninen Johanna, Hietanen Sakari, Carpén Olli, Lehtonen Rainer, Hautaniemi Sampsa, Huhtinen Kaisa
Geeniohjatun syövän hoidon työryhmä hoitopäätösten apuna : Läntisen syöpäkeskuksen kokemus (2021)
- Duodecim
Alanne Erika, Orte Katri, Haanpää Maria, Kankuri-Tammilehto Minna, Silvoniemi Maria, Sundvall Maria, Hietanen Sakari, Boström Pia, Laine Jukka, Jaakkola Panu, Minn Heikki, Kallajoki Markku, Kairisto Veli, Elenius Klaus, Vihinen Pia
Imaging of Tumor Hypoxia With F-18-EF5 PET/MRI in Cervical Cancer (2021)
- Clinical Nuclear Medicine
Narva Sara I., Seppänen Marko P., Raiko Juho R. H., Forsback Sarita J., Orte Katri J., Virtanen Johanna M., Hynninen Johanna, Hietanen Sakari
Molecular subtype diagnosis of endometrial carcinoma: comparison of the next-generation sequencing panel and Proactive Molecular Risk Classifier for Endometrial Cancer classifier (2021)
- Human Pathology
Huvila Jutta, Orte Katri, Vainio Paula, Mettälä Tuukka, Joutsiniemi Titta, Hietanen Sakari
PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples (2021)
- Bioinformatics
Häkkinen Antti, Zhang Kaiyang, Alkodsi Amjad, Andersson Noora, Pekcan Erkan Erdogan, Dai Jun, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Vähärautio Anna, Carpén Olli, Hynninen Johanna, Hietanen Sakari, Lehtonen Rainer, Hautaniemi Sampsa