Sakari Hietanen

- Docent,
Faculty of Medicine (University of Turku)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

sakari.hietanen@utu.fi

Publications

2 of 4

Real-life treatment patterns and time to next treatment among patients with ovarian cancer in the pre-PARP inhibitor era: the OCRWE-Finland Study (2024)
- Acta Oncologica
Lahelma, Mari; Rauhamaa, Heini; Isomeri, Outi; Idänpään-Heikkilä, Juhana; Käkelä, Sari; Roebuck, Nichola; Mascialino, Barbara; Hietanen, Sakari; Loukovaara, Mikko; Auranen, Annika
(A1 Refereed original research article in a scientific journal)
Circulating tumor DNA-based copy-number profiles enable monitoring treatment effects during therapy in high-grade serous carcinoma (2023)
- Biomedicine and Pharmacotherapy
Nguyen Mai TN, Rajavuori Anna, Huhtinen Kaisa, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa
(A1 Refereed original research article in a scientific journal)
Comorbidity of Urogynecological and Gastrointestinal Disorders in Female Patients With Lichen Sclerosus (2023)
- Journal of Lower Genital Tract Disease
Söderlund Jenni M, Hieta Niina K, Kurki Samu H, Orte Katri J, Polo-Kantola Päivi, Hietanen Sakari H, Haataja Marjut AM
(A1 Refereed original research article in a scientific journal)
Efficacy and safety of maintenance olaparib and bevacizumab in ovarian cancer patients aged ≥65 years from the PAOLA-1/ENGOT-ov25 trial (2023)
- European Journal of Cancer
Sabatier Renaud, Rousseau Frédérique, Joly Florence, Cropet Claire, Montégut Coline, Frindte Johanna, Cinieri Saverio, Guerra Alía Eva M, Polterauer Stephan, Yoshida Hiroyuki, Vergote Ignace, Colombo Nicoletta, Hietanen Sakari, Largillier Rémi, Canzler Ulrich, Gratet Alain, Marmé Frederick, Favier Laure, Pujade-Lauraine Eric, Ray-Coquard Isabelle
(A1 Refereed original research article in a scientific journal)
Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma (2023)
- Cancer Cell
Lahtinen Alexandra, Lavikka Kari, Virtanen Anni, Li Yilin, Jamalzadeh Sanaz, Skorda Aikaterini, Lauridsen Anna Rössberg, Zhang Kaiynag, Marchi Giovanni, Isoviita Veli-Matti, Ariotta Valeria, Lehtonen Oskari, Muranen Taru A., Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Senkowski Wojciech, Kallunki Tuula, Häkkinen Aantti, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa
(A1 Refereed original research article in a scientific journal)
Evolutionary study identifies poor prognosis HGSC patients and reveals clinically relevant targets at diagnosis and relapse2023
- International Journal of Gynecological Cancer
Oikkonen, Jaana; Lahtinen, Alexandra; Lavikka, Kari; Virtanen, Anni; Li, Yilin; Jamalzadeh, Sanaz; Skorda, Aikaterini; Lauridsen, Anna Rossberg; Zhang, Kaiyang; Marchi, Giovanni; Nguyen, Mai T. N.; Rajavuori, Anna; Muranen, Taru A.; Huhtinen, Kaisa; Hietanen, Sakari; Senkowski, Wojciech; Kallunki, Tuula; Hakkinen, Antti; Hynninen, Johanna; Hautaniemi, Sampsa
(Other publication)
Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes (2023)
- Clinical Cancer ResearchInternational Journal of Gynecological Cancer
Pikkusaari Sanna, Tumiati Manuela, Virtanen Anni, Oikkonen Jaana, Li Yilin, Perez-Villatoro Fernando, Muranen Taru, Salko Matilda, Huhtinen Kaisa, Kanerva Anna, Koskela Heidi, Tapper Johanna, Koivisto-Korander Riitta, Joutsiniemi Titta, Haltia Ulla-Maija, Lassus Heini, Hautaniemi Sampsa, Färkkilä Anniina, Hynninen Johanna, Hietanen Sakari, Carpen Olli, Kauppi Liisa
(A1 Refereed original research article in a scientific journal)
(2023)
- JCO Precision OncologyJCO Precision Oncology
Pujade-Lauraine E, Brown J, Barnicle A, Wessen J, Lao-Sirieix P, Criscione SW, du Bois A, Lorusso D, Romero I, Petru E, Yoshida H, Vergote I, Colombo N, Hietanen S, Provansal M, Schmalfeldt B, Pignata S, Lorente CM, Berton D, Runnebaum IB, Ray-Coquard I
(A1 Refereed original research article in a scientific journal)
Multi-omics characterization of chemo-refractory high-grade serous cancerOverall survival and patient-reported outcome results from the placebo-controlled randomized phase III IMagyn050/GOG 3015/ ENGOT-OV39 trial of atezolizumab for newly diagnosed stage III/IV ovarian cancer2023
Muranen, Taru A.; Afenteva, Daria; Rajavuori, Anna; Jamalzadeh, Sanaz; Zhang, Kaiyang; Ariotta, Valeria; Isoviita, Veli-Matti; Lahtinen, Alexandra; Lavikka, Kari; Lehtonen, Oskari; Li, Yilin; Marchi, Giovanni; Oikkonen, Jaana; Salloum, Shams; Huhtinen, Kaisa; Hietanen, Sakari; Virtanen, Anni; Hynninen, Johanna; Hautaniemi, Sampsa
(Other publication)
Normalized LST Is an Efficient Biomarker for Homologous Recombination Deficiency and Olaparib Response in Ovarian Carcinoma (2023)
Christinat Yann, Ho Liza, Clément Sophie, Genestie Catherine, Sehouli Jalid, Cinieri Saverio, Gonzalez Martin Antonio, Denison Ursula, Fujiwara Keiichi, Vergote Ignace, Tognon Germana, Hietanen Sakari, Ray-Coquard Isabelle, Pujade-Lauraine Eric, McKee Thomas A
(A1 Refereed original research article in a scientific journal)
(2023)
- Gynecologic Oncology
Pignata S, Bookman M, Sehouli J, Miller A, Penson RT, Taskiran C, Anderson C, Hietanen S, Myers T, Madry R, Willmott L, Lortholary A, Thomes-Pepin J, Aghajanian C, Mccourt C, Stuckey A, Wu XH, Nishio S, Copeland LJ, He YT, Molinero L, Patel S, Lin YG, Khor VK, Moore KN
(A1 Refereed original research article in a scientific journal)
Cisplatin overcomes radiotherapy resistance in OCT4-expressing head and neck squamous cell carcinoma (2022)
- Oral Oncology
Routila Johannes, Qiao Xi, Weltner Jere, Rantala Juha K, Carpén Timo, Hagström Jaana, Mäkitie Antti, Leivo Ilmo, Ruuskanen Miia, Söderlund Jenni, Rintala Marjut, Hietanen Sakari, Irjala Heikki, Minn Heikki, Westermarck Jukka, Ventelä Sami
(A1 Refereed original research article in a scientific journal)
Efficacy of niraparib by time of surgery and postoperative residual disease status: A post hoc analysis of patients in the PRIMA/ENGOT-OV26/GOG-3012 study (2022)
- Gynecologic Oncology
O'Cearbhaill Roisin E., Pérez-Fidalgo Jose-Alejandro, Monk Bradley J., Tusquets Ignacio, McCormick Colleen, Fuentes Jose, Moore Richard G., Vulsteke Christof, Shahin Mark S., Forget Frédéric, Bradley William H., Hietanen Sakari, O'Malley David M., Dørum Anne, Slomovitz Brian M., Baumann Klaus, Selle Frédéric, Calvert Paula M., Artioli Gracia, Levy Tally., Kumar Aalok, Malinowska Izabela A., Li Yong, Gupta Divya, González-Martín Antonio
(A1 Refereed original research article in a scientific journal)
Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer (2022)
- Science Advances
Zhang Kaiyang, Erkan Erdogan Pekcan, Jamalzadeh Sanaz, Dai Jun, Andersson Noora, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Oikkonen Jaana, Hynninen Johanna, Virtanen Anni, Häkkinen Antti, Hautaniemi Sampsa, Vähärautio Anna
(A1 Refereed original research article in a scientific journal)
Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer (2022)
- npj Precision Oncology
Perez-Villatoro Fernando, Oikkonen Jaana, Casado Julia, Chernenko Anastasiya, Gulhan Doga C., Tumiati Manuela, Li Yilin, Lavikka Kari, Hietanen Sakari, Hynninen Johanna, Haltia Ulla-Maija, Tyrmi Jaakko S., Laivuori Hannele, Konstantinopoulos Panagiotis A., Hautaniemi Sampsa, Kauppi Liisa, Färkkilä Anniina
(A1 Refereed original research article in a scientific journal)
QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability (2022)
- Laboratory Investigation
Jamalzadeh Sanaz, Häkkinen Antti, Andersson Noora, Huhtinen Kaisa, Laury Anna, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Carpén Olli, Virtanen Anni, Hautaniemi Sampsa
(A1 Refereed original research article in a scientific journal)
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality (2021)
- Scientific Reports
Jukonen Joonas, Moyano-Galceran Lidia, Höpfner Katrin, Pietilä Elina A, Lehtinen Laura, Huhtinen Kaisa, Gucciardo Erica, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Ojala Päivi M, Carpén Olli, Lehti Kaisa
(A1 Refereed original research article in a scientific journal)
Agile Workflow For Interactive Analysis Of Mass Cytometry Data (2021)
- Bioinformatics
Casado J, Lehtonen O, Rantanen V, Kaipio K, Pasquini L, Häkkinen A, Petrucci E, Hynninen J, Hietanen S, Carpén O, Biffoni M, Färkkilä A, Hautaniemi S
(A1 Refereed original research article in a scientific journal)
A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer (2021)
- Cancers
Salminen Liina, Braicu EIena, Lääperi Mitja, Jylhä Antti, Oksa Sinikka, Hietanen Sakari, Sehouli Jalid, Kulbe Hagen, du Bois Andras du, Mahner Sven, Harter Philipp, Carpen Oolli, Huhtinen Kaisa, Hynninen Johanna, Hilvo Mika
(A1 Refereed original research article in a scientific journal)
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021)
- Nature Communications
Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
(A1 Refereed original research article in a scientific journal)