Alex Dickens - UTU Research Portal

Alex Dickens

- Academy Research Fellow,
Turku Bioscience Centre (Independent units)
- Docent,
Department of Life Technologies (Faculty of Technology)
- Academy Research Fellow,
Analytiikkakeskus (Department of Chemistry)

alex.dickens@utu.fi

: https://orcid.org/0000-0002-3178-8449

Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

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(2017)
- Scientific ReportsGlia
Dickens AM, Yoo SW, Chin AC, Xu JD, Johnson TP, Trout AL, Hauser KF, Haughey NJ
HIV Tat protein and amyloid-beta peptide form multifibrillar structures that cause neurotoxicityA TRPML1 agonist facilitates lysosomal clearance of proteins and lipids in a mouse model of gp120 facilitated amyloid deposition (2017)
- Nature Structural and Molecular BiologyJournal of NeuroVirology
Hategan A, Bianchet MA, Steiner J, Karnaukhova E, Masliah E, Fields A, Lee MH, Dickens AM, Haughey N, Dimitriadis EK, Nath A
Impaired Insulin Sensitivity Indicates Worsening Cognitive Function in HIV-infected Patients2017
- Journal of Neuroimmune PharmacologyNeurology
Khuder S, Kim S, Letendre S, Marcotte I, Saktor N, McArthur JC, Dickens AM, Haughey NJ
Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation (2017)
- Stroke
Couch Y, Akbar N, Davis S, Fischer R, Dickens AM, Neuhaus AA, Burgess AI, Rothwell PM, Buchan AM
(2017)
- Frontiers in NeurologyAnnals of Clinical and Translational Neurology
Jussi P. Posti, Alex M. Dickens, Matej Orešič, Tuulia Hyötyläinen, Olli Tenovuo
Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients (2017)
- AIDS
Ubaida-Mohien C, Lamberty B, Dickens AM, Mielke MM, Marcotte T, Sacktor N, Grant I, Letendre S, Franklin D, Cibrowski P, Tharakan R, McArthur JC, Fox H, Haughey NJ
Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice (2016)
- Theranostics
Larkin JR, Dickens AM, Claridge TDW, Bristow C, Andreou K, Anthony DC, Sibson NR
EARLY DIAGNOSIS OF BRAIN TUMOURS THROUGH BIOFLUID METABOLOMICS (2016) Larkin JR, Dickens AM, Claridge TDW, Anthony DC, Sibson NR
HIV-associated neurocognitive disorder - pathogenesis and prospects for treatment (2016)
- Nature Reviews Neurology
Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC
HIV-associated neurocognitive disorder - pathogenesis and prospects for treatment (vol 12, pg 234, 2016) (2016)
- Nature Reviews Neurology
Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC
Anti-VLA-4 treatment reduces microglial activation in a focal EAE-model (2015)
Vainio S, Dickens AM, Tuisku J, Eskola O, Solin O, Anthony D, Haaparanta-Solin M, Rinne J, Airas L
(2015)
Yoo SW, Trout AL, Lovett J, Dickens AM, Xu HX, Haughey NJ
Interictal, circulating sphingolipids in women with episodic migraine A case-control study (2015)
Peterlin BL, Mielke MM, Dickens AM, Chatterjee S, Dash P, Alexander G, Vieira RV, Bandaru VVR, Dorskind JM, Tietjen GE, Haughey NH
In Vivo PET Imaging Demonstrates Diminished Microglial Activation After Fingolimod Treatment in an Animal Model of Multiple Sclerosis (2015)
- Journal of Nuclear Medicine
Airas L, Dickens A, Elo P, Marjamäki, P, Johansson J, Eskola O, Jones P, Trigg W, Solin O, Haaparanta-Solin M, Anthony D, Rinne J
Microglial activation correlates with disease progression in multiple sclerosis (2015) E. Rissanen, J. Tuisku, M. Gardberg, A.M. Dickens, M. Sucksdorff, J. Rokka, T. Paavilainen, R. Parkkola, J.O. Rinne, L. Airas
Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain (2014)
Anthony DC, Dickens AM, Seneca N, Couch Y, Campbell S, Checa B, Kersemans V, Warren EA, Tredwell M, Sibson NR, Gouverneur V, Leppert D
Anti-CD20 therapy down-regulates lesion formation and microglial activation in pattern I and pattern II rat models of multiple sclerosis (2014)
- Journal of Neuroimmunology
Anthony DC, Dickens AM, Seneca N, Couch Y, Campbell S, Checa B, Kersemans V, Warren EA, Tredwell M, Sibson NR, Gouverneur V, Leppert D
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis (2014)
- Neurology
Dickens AM, Larkin JR, Griffin JL, Cavey A, Matthews L, Turner MR, Wilcock GK, Davis BG, Claridge TDW, Palace J, Anthony DC, Sibson NR
Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180 (2014)
- Journal of Nuclear Medicine
Alex M. Dickens, Susanne Vainio, Päivi Marjamäki, Jarkko Johansson, Paula Lehtiniemi, Johanna Rokka, Juha Rinne, Olof Solin, Merja Haaparanta-Solin, Paul A. Jones, William Trigg, Daniel C. Anthony, Laura Airas
Longitudinal changes in CSF metabolites as a prognostic marker for cognition in HIV-infected patients (2014)
- Journal of Neuroimmune Pharmacology
Dickens AM, Anthony DC, Mielke MM, Claridge TDW, Deutsch R, Grant I, Letendre S, Marcotte T, McArthur JC, Haughey NJ