Alex Dickens - UTU Research Portal

Alex Dickens

- Academy Research Fellow,
Turku Bioscience Centre (Independent units)
- Docent,
Department of Life Technologies (Faculty of Technology)
- Academy Research Fellow,
Analytiikkakeskus (Department of Chemistry)

alex.dickens@utu.fi

: https://orcid.org/0000-0002-3178-8449

Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

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Impaired insulin sensitivity is associated with worsening cognition in HIV-infected patients (2019)
- Neurology
Khuder SS, Chen SM, Letendre S, Marcotte T, Grant I, Franklin D, Rubin LH, Margolick JB, Jacobson LP, Sacktor N, D'Souza G, Stosor V, Lake JE, Rapocciolo G, McArthur JC, Dickens AM, Haughey NJ, Haughey NJ
Lipidomic characterization of extracellular vesicles in human serum (2019)
- Journal of Circulating Biomarkers
Chen S., Datta-Chaudhuri A., Deme P., Dickens A., Dastgheyb R., Bhargava P., Bi H., Haughey N.J.
Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry (2019)
- Analytical and Bioanalytical Chemistry
Samira Salihović, Alex M. Dickens, Ida Schoultz, Frida Fart, Lisanna Sinisalu, Tuomas Lindeman, Jonas Halfvarson, Matej Orešič, Tuulia Hyötyläinen
The Role of Omic Technologies in the Study of the Human Gut Microbiome (2019) Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
An Overview of Metabolomics Data Analysis: Current Tools and Future Perspectives (2018) Comprehensive Analytical Chemistry Lamichhane S., Sen P., Dickens A., Hyötyläinen T., Orešič M.
Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe (2018)
- Methods
Santosh Lamichhane, Partho Sen, Alex M.Dickens, Matej Orešič, Hanne Christine Bertram
Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury (2018)
- Journal of NeurotraumaFrontiers in Neurology
Dickens AM, Posti JP, Takala RSK, Ala-Seppala H, Mattila I, Coles JP, Frantzen J, Hutchinson PJ, Katila AJ, Kyllonen A, Maanpaa HR, Newcombe V, Outtrim J, Tallus J, Carpenter KLH, Menon DK, Hyotylainen T, Tenovuo O, Oresic M, Oresic M
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions (2017)
- Science SignalingAIDS
Dickens AM, Tovar-y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ
Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging (2017)
- Scientific Reports
Dickens AM, Yoo SW, Chin AC, Xu JD, Johnson TP, Trout AL, Hauser KF, Haughey NJ
HIV Tat protein and amyloid-beta peptide form multifibrillar structures that cause neurotoxicity (2017)
- Nature Structural and Molecular BiologyNature Reviews Neurology
Hategan A, Bianchet MA, Steiner J, Karnaukhova E, Masliah E, Fields A, Lee MH, Dickens AM, Haughey N, Dimitriadis EK, Nath A
Impaired Insulin Sensitivity Indicates Worsening Cognitive Function in HIV-infected PatientsHIV-associated neurocognitive disorder - pathogenesis and prospects for treatment (vol 12, pg 234, 2016) (2017)
- Journal of Neuroimmune Pharmacology
Khuder S, Kim S, Letendre S, Marcotte I, Saktor N, McArthur JC, Dickens AM, Haughey NJ
Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation (2017)
- StrokeGlia
Couch Y, Akbar N, Davis S, Fischer R, Dickens AM, Neuhaus AA, Burgess AI, Rothwell PM, Buchan AM
Metabolomics profiling as a diagnostic tool in severe traumatic brain injuryA TRPML1 agonist facilitates lysosomal clearance of proteins and lipids in a mouse model of gp120 facilitated amyloid deposition (2017)
Jussi P. Posti, Alex M. Dickens, Matej Orešič, Tuulia Hyötyläinen, Olli Tenovuo
Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients (2017)
Ubaida-Mohien C, Lamberty B, Dickens AM, Mielke MM, Marcotte T, Sacktor N, Grant I, Letendre S, Franklin D, Cibrowski P, Tharakan R, McArthur JC, Fox H, Haughey NJ
Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice (2016)
- Theranostics
Larkin JR, Dickens AM, Claridge TDW, Bristow C, Andreou K, Anthony DC, Sibson NR
EARLY DIAGNOSIS OF BRAIN TUMOURS THROUGH BIOFLUID METABOLOMICS (2016) Larkin JR, Dickens AM, Claridge TDW, Anthony DC, Sibson NR
HIV-associated neurocognitive disorder - pathogenesis and prospects for treatment (2016)
Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC
(2016)
- Nature Reviews Neurology
Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC
Anti-VLA-4 treatment reduces microglial activation in a focal EAE-model (2015)
Vainio S, Dickens AM, Tuisku J, Eskola O, Solin O, Anthony D, Haaparanta-Solin M, Rinne J, Airas L
(2015)
- Journal of NeuroVirology
Yoo SW, Trout AL, Lovett J, Dickens AM, Xu HX, Haughey NJ