Alex Dickens - UTU Research Portal

Alex Dickens

- Academy Research Fellow,
Turku Bioscience Centre (Independent units)
- Docent,
Department of Life Technologies (Faculty of Technology)
- Academy Research Fellow,
Analytiikkakeskus (Department of Chemistry)

alex.dickens@utu.fi

ORCID identifier: https://orcid.org/0000-0002-3178-8449

Areas of expertise

Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

Publications

2 of 4

Lower abdominal adipose tissue cannabinoid type 1 receptor availability in young men with overweight (2023)
- Obesity
Pekkarinen L., Kantonen T., Oikonen V., Haaparanta-Solin M., Aarnio R., Dickens A.M., von Eyken A., Latva-Rasku A., Dadson P., Kirjavainen A.K., Rajander J., Kalliokoski K., Rönnemaa T., Nummenmaa L., Nuutila P.
(A1 Refereed original research article in a scientific journal)
Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation (2022)
- EJNMMI Research
Vainio SK, Dickens AM, Matilainen M, Lopez-Picon FR, Aarnio R, Eskola O, Solin O, Anthony DC, Rinne JO, Airas L, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes (2022)
- Cell Reports Medicine
Lamichhane Santosh, Sen Partho, Dickens Alex M., Alves Marina Amaral, Härkönen Taina, Honkanen Jarno, Vatanen Tommi, Xavier Ramnik J., Hyötyläinen Tuulia, Knip Mikael, Oresic Matej
(A1 Refereed original research article in a scientific journal)
Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study (2022)
- Cannabis and Cannabinoid Research
Chester Lucy A., Englund Amir, Chesney Edward, Oliver Dominic, Wilson Jack, Sovi Simina, Dickens Alex M., Oresic Matej, Linderman Tuomas, Hodsoll John, Minichino Amedeo, Strang John, Murray Robin M., Freeman Tom P., McGuire Philip
(A1 Refereed original research article in a scientific journal)
Metabolomic and proteomic profiling in bipolar disorder patients revealed potential molecular signatures related to hemostasis (2022)
- Metabolomics
Caracho Ribeiro Henrique, Sen Partho, Dickens Alex, Santa Cruz Elisa Castañeda, Orešič Matej, Sussulini Alessandra
(A1 Refereed original research article in a scientific journal)
Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability (2022)
- International Journal of Obesity
Kantonen Tatu, Pekkarinen Laura, Karjalainen Tomi, Bucci Marco, Kalliokoski Kari, Haaparanta-Solin Merja, Aarnio Richard, Dickens Alex M., von Eyken Annie, Laitinen Kirsi, Houttu Noora, Kirjavainen Anna K., Helin Semi, Hirvonen Jussi, Rönnemaa Tapani, Nuutila Pirjo, Nummenmaa Lauri
(A1 Refereed original research article in a scientific journal)
Serum metabolome associated with severity of acute traumatic brain injury (2022)
- Nature Communications
Thomas Ilias, Dickens Alex M, Posti Jussi P, Czeiter Endre, Duberg Daniel, Sinioja Tim, Kråkström Matilda, Helmrich Isabel RA Retel, Wang Kevin KW, Maas Andrew IR, Steyerberg Ewout W, Menon David K, Tenovuo Olli, Hyötyläinen Tuulia, Büki András, Orešič Matej; Group author: CENTER-TBI Participants and Investigators
(A1 Refereed original research article in a scientific journal)
Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis (2021)
- Schizophrenia Bulletin
Lamichhane Santosh, Dickens Alex M, Sen Partho, Laurikainen Heikki, Borgan Faith, Suvisaari Jaana, Hyötyläinen Tuulia, Howes Oliver, Hietala Jarmo, Orešič Matej
(A1 Refereed original research article in a scientific journal)
Deep learning meets metabolomics: a methodological perspective (2021)
- Briefings in Bioinformatics
Partho Sen, Santosh Lamichhane, Vivek B Mathema, Aidan McGlinchey, Alex M Dickens, Sakda Khoomrung, Matej Orešič
(A2 Refereed review article in a scientific journal )
Dysregulated lipid metabolism precedes onset of psychosis (2021)
- Biological Psychiatry
Alex M Dickens, Partho Sen, Matthew J Kempton, Neus Barrantes-Vidal, Conrad Iyegbe, Merete Nordentoft, Thomas Pollak, Anita Riecher-Rössler, Stephan Ruhrmann, Gabriele Sachs, Rodrigo Bressan, Marie-Odile Krebs, G Paul Amminger, Lieuwe de Haan, Mark van der Gaag, Lucia Valmaggia, Tuulia Hyötyläinen, Matej Orešič, Philip McGuire
(A1 Refereed original research article in a scientific journal)
Lihomisriski on yhteydessä aivojen insuliini- ja reseptorimuutoksiin (2021)
- Duodecim
Kantonen T., Pekkarinen L., Karjalainen T., Bucci M., Kalliokoski K., Haaparanta-Solin M., Aarnio R., Dickens A.M., von Eyken A., Laitinen K., Houttu N., Kirjavainen A.K., Helin S., Hirvonen J., Rönnemaa T., Nuutila P., Nummenmaa L.
(Other publication)
Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways (2021)
- Cell Reports
Partho Sen, Syed Bilal Ahmad Andrabi, Tanja Buchacher, Mohd Moin Khan, Ubaid Ullah Kalim, Tuomas Mikael Lindeman, Marina Amaral Alves, Victoria Hinkkanen, Esko Kemppainen, Alex M Dickens, Omid Rasool, Tuulia Hyötyläinen, Riitta Lahesmaa, Matej Orešič
(A1 Refereed original research article in a scientific journal)
Systems biology approaches to study lipidomes in health and disease (2021)
- Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
Marina Amaral Alves, Santosh Lamichhane, Alex Dickens, Aidan McGlinchey, Henrique C Ribeiro, Partho Sen, Fang Wei, Tuulia Hyötyläinen, Matej Orešič
(A2 Refereed review article in a scientific journal )
Integrative Analysis of Circulating Metabolite Profiles and Magnetic Resonance Imaging Metrics in Patients with Traumatic Brain Injury (2020)
- International Journal of Molecular Sciences
Ilias Thomas, Alex M. Dickens, Jussi P. Posti, Mehrbod Mohammadian, Christian Ledig, Riikka S. K. Takala, Tuulia Hyötyläinen, Olli Tenovuo, Matej Orešič
(A1 Refereed original research article in a scientific journal)
Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis (2020)
- NPJ Schizophrenia
Dickens Alex M, Borgan Faith, Laurikainen Heikki, Lamichhane Santosh, Marques Tiago, Rönkkö Tuukka, Veronese Mattia, Lindeman Tuomas, Hyötyläinen Tuulia, Howes Oliver, Hietala Jarmo, Orešič Matej
(A1 Refereed original research article in a scientific journal)
Metabolic alterations in immune cells associate with progression to type 1 diabetes (2020)
- Diabetologia
Partho Sen, Alex M. Dickens, María Asunción López-Bascón, Tuomas Lindeman, Esko Kemppainen, Santosh Lamichhane, Tuukka Rönkkö, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Heikki Hyöty, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič
(A1 Refereed original research article in a scientific journal)
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes (2020)
- Environment International
Aidan McGlinchey, Tim Sinioja, Santosh Lamichhane, Partho Sen, Johanna Bodin, Heli Siljander, Alex M Dickens, Dawei Geng, Cecilia Carlsson, Daniel Duberg, Jorma Ilonen, Suvi M Virtanen, Hubert Dirven, Hanne F Bentsen, Karin Zimmer, Unni C Nygaard, Matej Oresic, Mikael Knip, Tuulia Hyotylainen
(A1 Refereed original research article in a scientific journal)
Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation (2019)
- EJNMMI Research
Vainio SK, Dickens AM, Tuisku J, Eskola O, Solin O, Loyttyniemi E, Anthony DC, Rinne JO, Airas L, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes (2019)
- Biomolecules
Lamichhane Santosh, Ahonen Linda, Dyrlund Thomas Spartholt, Dickens Alex M., Siljander Heli, Hyöty Heikki, Ilonen Jorma, Toppari Jorma, Veijola Riitta, Hyötyläinen Tuulia, Knip Mikael, Oresic Matej
(A1 Refereed original research article in a scientific journal)
Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury (2019)
- Journal of Neurotrauma
Posti JP, Takala RS, Lagerstedt L, Dickens AM, Hossain I, Mohammadian M, Ala-Seppälä HM, Frantzén J, Van Gils M, Hutchinson PJ, Katila AJ, Maanpää HR, Menon D, Newcombe V, Tallus J, Hrusovsky K, Wilson D, Gill J, Sanchez JC, Tenovuo O, Zetterberg H, Blennow K.
(A1 Refereed original research article in a scientific journal)