Teijo Saari
MD, PhD. Head of Department
teisaa@utu.fi ORCID identifier: https://orcid.org/0000-0003-1225-4561(external) |
Pain medicine; Analgesia; Modelling & Simulation; Pharmacometrics; Clinical Pharmacology; Drug-Drug-Interactions
Precise and new therapeutic possibilities to acute pain medicine. Prevention of subsequent subacute pain and development chronic pain
Professor Teijo Saari (MD, PhD, University of Turku) is a specialist in anesthesiology and intensive care and cardiac anesthesia at the Turku University Hospital, Turku, Finland. Since 2004, he has been conducting research on clinical pharmacology examining the pain therapeutics and anesthetics and developing pharmacometric models for precise drug dosing. His PhD work evaluated drug-drug interactions between antimycotes and drugs used in anesthesiology and pain medicine (University of Turku, April 2005). In 2011-2013 he worked as post doctoral fellow in University of Erlangen-Nuremberg, Germany in pharmacometric research project: ’PEP’ – Personalized Effect-Controlled Pharmacotherapy. Since 2013, he has lead his research group focusing on acute pain medicine. In January 2017, he was appointed to Tenure Track as Associate Professor and in June 2021 as Full Professor and Chairman of Anesthesiology and Intensive Care at the University of Turku.
His career publications total is 64 (h-index 26) with published highlights including high-ranked papers in Anesthesiology, British Journal of Anesthesiology and Clinical Pharmacokinetics.
Professor Saari's principal research focus has been to provide novel information on therapeutics used in acute pain medicine. Beginning from 2013 he has led a research group with special interest on model-informed precision dosing and development of new dosing modalities for pain therapeutics. Important aspect of his research has been a pursuit to reduce opioid use with adjuvants added to the opioid therapy in the postoperative setting. His work has demonstrated that pharmacometric models can improve the precision of drug dosing during postoperative phase. Furthermore, his studies have established covariate effects explaining between-patient variability. His future aim is to discover biomarkers that can predict chronic pain development.
Teaching responsibilities: 1) Anesthesiology and Intensive care for medical students, 2) Graduate studies for MDs
Special interest areas: Acute pain medicine, cardiac anesthesia, clinical pharmacology
- Alfentaniili (2022) Akuuttihoidon lääkkeet Bendel Stepani, Saari Teijo
(D2 Article in a professional compilation book) - Fentanyyli (2022) Akuuttihoidon lääkkeet Bendel Stepani, Saari Teijo, Hoppu Sanna
(D2 Article in a professional compilation book) - Kokonaisvaltaisesti kivusta tutkijan ja kokijan silmin (2022)
- Finnanest
(D1 Article in a professional journal) - Leikkausta edeltävä arviointi ja leikkausriskien hallinta (2022) Anestesiologian ja tehohoidon perusteet Ahlmén-Laiho Ulla, Niemi-Murola Leila, Saari Teijo
(D2 Article in a professional compilation book) - Morfiini (2022) Akuuttihoidon lääkkeet Bendel Stepani, Saari Teijo, Hoppu Sanna
(D2 Article in a professional compilation book) - Nestehoito (2022) Anestesiologian ja tehohoidon perusteet Huttunen Tuomas, Saari Teijo, Niemi-Murola Leila
(D2 Article in a professional compilation book) - Oksikodoni (2022) Akuuttihoidon lääkkeet Bendel Stepani, Saari Teijo, Hoppu Sanna
(D2 Article in a professional compilation book) - Remifentaniili (2022) Akuuttihoidon lääkkeet Bendel Stepani, Saari Teijo
(D2 Article in a professional compilation book) - Tietoruutu L34. Hätätilapotilaan hoidossa käytettäviä lääkkeitä (2022) Farmakologia ja toksikologia Saari Teijo
(D2 Article in a professional compilation book) - Anestesia-aineiden farmakokinetiikka ja farmakodynamiikka lapsilla (2021) Anestesiologia, teho-, ensi- ja kivunhoito Saari Teijo
(D2 Article in a professional compilation book) - Anestesiologia kehittyy leikkaussalien ulkopuolella (2021)
- Duodecim
(D1 Article in a professional journal) - Anestesiologia, teho-, ensi- ja kivunhoito (2021) Olkkola Klaus, Kiviluoma Kai, Saari Teijo, Tallgren Minna, Uusaro Ari, Yli-Hankala Arvi
(D6 Editorial work for a professional compilation book) - Effects of pre-emptive pregabalin and multimodal anesthesia on postoperative opioid requirements in patients undergoing robot-assisted laparoscopic prostatectomy (2021)
- BMC Urology
(A1 Refereed original research article in a scientific journal) - Intranasal Dexmedetomidine Reduces Postoperative Opioid Requirement in Patients Undergoing Total Knee Arthroplasty Under General Anesthesia (2021)
- Journal of Arthroplasty
(A1 Refereed original research article in a scientific journal) - Lääkeainemetabolian muutokset akuutisti sairaalla (2021) Peruselintoimintojen häiriöt ja niiden hoito Olkkola Klaus, Saari Teijo
(D2 Article in a professional compilation book) - Parasetamoli akuutin kivun hoidossa (2021) Anestesiologia, teho-, ensi- ja kivunhoito Salomäki Timo, Saari Teijo
(D2 Article in a professional compilation book) - Perinteiset ja COX-2-selektiiviset tulehduskipulääkkeet (2021) Anestesiologia, teho-, ensi- ja kivunhoito Salomäki Timo, Saari Teijo
(D2 Article in a professional compilation book) - Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis (2021)
- Journal of Clinical Pharmacology
(A1 Refereed original research article in a scientific journal) - Sähköisten terveyspalveluiden opetus lääketieteessä (2021)
- Duodecim
(D1 Article in a professional journal) - S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial (2021)
- PLoS ONE
(A1 Refereed original research article in a scientific journal)