Teijo Saari
MD, PhD. Head of Department
teisaa@utu.fi ORCID identifier: https://orcid.org/0000-0003-1225-4561 |
Pain medicine; Analgesia; Modelling & Simulation; Pharmacometrics; Clinical Pharmacology; Drug-Drug-Interactions
Precise and new therapeutic possibilities to acute pain medicine. Prevention of subsequent subacute pain and development chronic pain
Professor Teijo Saari (MD, PhD, University of Turku) is a specialist in anesthesiology and intensive care and cardiac anesthesia at the Turku University Hospital, Turku, Finland. Since 2004, he has been conducting research on clinical pharmacology examining the pain therapeutics and anesthetics and developing pharmacometric models for precise drug dosing. His PhD work evaluated drug-drug interactions between antimycotes and drugs used in anesthesiology and pain medicine (University of Turku, April 2005). In 2011-2013 he worked as post doctoral fellow in University of Erlangen-Nuremberg, Germany in pharmacometric research project: ’PEP’ – Personalized Effect-Controlled Pharmacotherapy. Since 2013, he has lead his research group focusing on acute pain medicine. In January 2017, he was appointed to Tenure Track as Associate Professor and in June 2021 as Full Professor and Chairman of Anesthesiology and Intensive Care at the University of Turku.
His career publications total is 64 (h-index 26) with published highlights including high-ranked papers in Anesthesiology, British Journal of Anesthesiology and Clinical Pharmacokinetics.
Professor Saari's principal research focus has been to provide novel information on therapeutics used in acute pain medicine. Beginning from 2013 he has led a research group with special interest on model-informed precision dosing and development of new dosing modalities for pain therapeutics. Important aspect of his research has been a pursuit to reduce opioid use with adjuvants added to the opioid therapy in the postoperative setting. His work has demonstrated that pharmacometric models can improve the precision of drug dosing during postoperative phase. Furthermore, his studies have established covariate effects explaining between-patient variability. His future aim is to discover biomarkers that can predict chronic pain development.
Teaching responsibilities: 1) Anesthesiology and Intensive care for medical students, 2) Graduate studies for MDs
Special interest areas: Acute pain medicine, cardiac anesthesia, clinical pharmacology
- Exploring care pathways of patients conveyed by emergency medical services (EMS) through electronic health records (2025)
- Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
(A1 Refereed original research article in a scientific journal) - Premedication with intranasal dexmedetomidine in patients undergoing total knee arthroplasty under spinal anaesthesia (TKADEX)—a prospective, double-blinded, randomised controlled trial (2025)
- BJA Open
(A1 Refereed original research article in a scientific journal) - Absorption pharmacokinetics and feasibility of intranasal dexmedetomidine in patients under general anaesthesia (2024)
- Acta Anaesthesiologica Scandinavica
(A1 Refereed original research article in a scientific journal) - Anestesian periaatteet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Clinical Pharmacokinetics and Pharmacodynamics of Naloxone (2024)
- Clinical Pharmacokinetics
(A2 Refereed review article in a scientific journal ) - Depolarisoivat lihasrelaksantit (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Hermo-lihasliitosta lamaavat lääkeaineet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Inhalaatioanestesia-aineet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Inhalaatioanestesia-aineiden ominaisuudet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Laskimoanestesia-aineet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Lihasrelaksaation antagonisointi yleisanestesian yhteydessä (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Lihasrelaksanttien yhteisvaikutukset (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Muussa kuin anestesiakäytössä olevat hermo-lihas-liitokseen vaikuttavat aineet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Nondepolarisoivat lihasrelaksantit (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Population Pharmacokinetic Quantification of CYP2D6 Activity in Codeine Metabolism in Ambulatory Surgical Patients for Model-Informed Precision Dosing (2024)
- Clinical Pharmacokinetics
(A1 Refereed original research article in a scientific journal) - Puuduteaineet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Puudutteiden haittavaikutukset (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Puudutteiden ominaisuudet (2024) Lääketieteellinen farmakologia ja toksikologia Olkkola, Klaus T.; Saari, Teijo
(D2 Article in a professional compilation book) - Suositus kotiutumisen edellytyksistä päiväkirurgisen anestesiaa edellyttävän toimenpiteen jälkeen (yli 18-vuotiaat) (2024)
- Finnanest
(D1 Article in a professional journal) - Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial (2023)
- Trials
(A1 Refereed original research article in a scientific journal)