Aleksi Isomursu

- Doctoral Candidate,
- Doctoral Researcher
Turku Bioscience Centre (Independent units)

aleksi.isomursu@utu.fi

Biomechanics of cancer cell motility (2024) Isomursu Aleksi
Positive and negative durotaxis - mechanisms and emerging concepts (2024)
- Journal of Cell Science
Mathieu Mathilde, Isomursu Aleksi, Ivaska Johanna
Spatiotemporal control over cell-matrix interactions using dynamic micropatterns (2024)
- Nature Reviews Molecular Cell Biology
Isomursu Aleksi
Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling (2023)
- Proceedings of the National Academy of Sciences of the United States of America
Conway James R.W., Isomursu Aleksi, Follain Gautier, Härmä Ville, Jou-Ollé Eva, Pasquier Nicolas, Välimäki Eetu P.O., Rantala Juha K., Ivaska Johanna
Dynamic Micropatterning Reveals Substrate-Dependent Differences in the Geometric Control of Cell Polarization and Migration (2023)
- Small Methods
Isomursu Aleksi, Alanko Jonna, Hernández-Pérez Sara, Saukkonen Karla, Saari Markku, Mattila Pieta K., Ivaska Johanna
PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers (2023)
- Molecular Oncology
Aakula Anna, Isomursu Aleksi, Rupp Christian, Erickson Andrew, Gupta Nikhil, Kauko Otto, Shah Pragya, Padzik Artur, Pokharel Yuba Raj, Kaur Amanpreet, Li Song-Ping, Trotman Lloyd, Taimen Pekka, Rannikko Antti, Lammerding Jan, Paatero Ilkka, Mirtti Tuomas, Ivaska Johanna, Westermarck Jukka
Directed cell migration towards softer environments (2022)
- Nature Materials
Isomursu Aleksi, Park Keun-Young, Hou Jay, Cheng Bo, Mathieu Mathilde, Shamsan Ghaidan A., Fuller Benjamin, Kasim Jesse, Mahmoodi M. Mohsen, Lu Tian Jian, Genin Guy M., Xu Feng, Lin Min, Distefano Mark D., Ivaska Johanna, Odde David J.
MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels (2022)
- iScience
Närvä Elisa, Taskinen Maria E, Lilla Sergio, Isomursu Aleksi, Pietilä Mika, Weltner Jere, Isola Jorma, Sihto Harri, Joensuu Heikki, Zanivan Sara, Norman Jim, Ivaska Johanna
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries (2022)
- Developmental Cell
Peuhu Emilia, Jacquemet Guillaume, Scheele Colinda LGJ, Isomursu Aleksi, Laisne Marie-Catherine, Koskinen Leena M, Paatero Ilkka, Thol Kerstin, Georgiadou Maria, Guzmán Camilo, Koskinen Satu, Laiho Asta, Elo Laura L, Boström Pia, Hartiala Pauliina, van Rheenen Jacco, Ivaska Johanna
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling (2021)
- Current Biology
Salomaa Siiri I, Miihkinen Mitro, Kremneva Elena, Paatero Ilkka, Lilja Johanna, Jacquemet Guillaume, Vuorio Joni, Antenucci Lina, Kogan Konstantin, Hassani Nia Fatemeh, Hollos Patrik, Isomursu Aleksi, Vattulainen Ilpo, Coffey Eleanor T, Kreienkamp Hans-Jürgen, Lappalainen Pekka, Ivaska Johanna
Mechano-responsiveness of fibrillar adhesions on stiffness-gradient gels (2020)
- Journal of Cell Science
Barber-Pérez N, Georgiadou M, Guzmán C, Isomursu A, Hamidi H, Ivaska J
Combined inhibition of tumor suppressors PTEN and PP2A drives anoikis resistance and is associated with therapy relapse in prostate cancer (2019)
- Cancer Research
Rupp C, Isomursu A, Aakula A, Erickson A, Li SP, Kaur A, Shah P, Pokharel YR, Trottman L, Lammerding J, Rannikko A, Taimen P, Mirtti T, Paatero I, Ivaska J, Westermarck JK
Integrin signaling and mechanotransduction in regulation of somatic stem cells (2019)
- Experimental Cell Research
Isomursu A., Lerche M., Taskinen M.E., Ivaska J., Peuhu E.