Michal Hubacek
Mgr. (Master's degree in Molecular Biology and Genetics)
Photosynthetic Microbes michal.hubacek@utu.fi ORCID-tunniste: https://orcid.org/0000-0001-6507-7840 |
photosynthesis; cyanobacteria; whole-cell biotransformation
Photosynthetic Microbes research group
Erasmus+ Traineeship (2018 - 2019) at Bioprocess Engineering group - supervised by prof. Maria Barbosa
Project: Tailored microalgae as sustainable oil crop producing platforms
Wageningen University & Research, Wageningen, the Netherlands
Masters in Molecular Biology and Genetics (2017 - 2020)
Thesis: Development and analysis of seawater microalgae novel mutant lines using modern breeding methods
Masaryk University, Brno, Czech Republic
Bachelor in Molecular Biology and Genetics (2014 - 2017)
Thesis: Utilisation of non-canonical amino acids in protein engineering
Masaryk University, Brno, Czech Republic
The current pace of the use of fossil fuels is unsustainable from several points of view. Be it the political implications of resource dependency or the severe impacts on our climate and environment. Photosynthetic microorganisms provide a promising alternative feedstock for various applications, such as biofuels, fine chemicals or high-value compounds. However, more research is needed to make them
economically competitive.
My project attempts to fill a knowledge gap within the field of whole-cell biocatalysis. by understanding the cell’s response to electron sink engineering and explaining the underlying regulation of photosynthesis in nonstandard conditions. The first results suggest the active enzyme's substantial effect on the photosynthetic apparatus. The second half will focus on engineering attempts to enhance biocatalytic efficiency. The outcomes of my project will push the transition towards green chemicals by providing knowledge and concrete strain development strategies.
- Flavodiiron proteins associate pH-dependently with the thylakoid membrane for ferredoxin-1-powered O2 photoreduction (2025)
- New Phytologist
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Strong heterologous electron sink outcompetes alternative electron transport pathways in photosynthesis (2024)
- Plant Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Towards the rate limit of heterologous biotechnological reactions in recombinant cyanobacteria (2023)
- Biotechnology for Biofuels and Bioproducts
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Photosynthetic microorganisms as biocatalysts (2021) Photosynthesis: Biotechnological Applications with Microalgae Nikkanen Lauri, Hubacek Michal, Allahverdiyeva Yagut
(A3 Vertaisarvioitu kirjan tai muun kokoomateoksen osa)