Heli Harvala
MD, PhD, EUPHEM Alumni, FRCPath
Virology heli.harvala@utu.fi ORCID identifier: https://orcid.org/0000-0001-9154-4190 |
Virology; Clinical Virology; Public Health Virology; Transfusion Virology
Heli Harvala was appointed as a Professor of Virology at the Institute of Biomedicine, University of Turku, Finland in September, 2024.
She graduated in Medicine, obtained a MSc in Organic Chemistry and a PhD in Virology at the University of Turku, Finland, in 2003. Subsequently she completed her Medical Virology training in Edinburgh and became a Fellow of the Royal College of Pathologists in 2015. During that time, she joined the European Public Health Microbiology fellowship programme at the Public Health Agency of Sweden for two years before returning back to the UK. Over the last ten years, she has combined her work as a Consultant Medical Virologist with clinical, transfusion and public health related virology research.
She is a co-founder of the European Non-Polio Enterovirus Network (ENPEN) which evaluates the importance of enterovirus infections and monitors for their emergence together with collaborators from over 30 European countries. During COVID-19 pandemic, she was involved with setting up SARS-CoV-2 testing of convalescent plasma donors in England, and the related international REMAP-CAP trial. She also has wide interests in molecular epidemiology and next generation sequencing, and is involved with investigations into how next generation sequencing could be used to enhance the effectiveness of microbiological donation screening.
She leads the Blood Safety research team within the NIHR funded Blood and Transplant Research Unit at the University of Oxford. This research focuses on transfusion transmitted viral infections aiming to improve our understanding of current risks and preparedness for emerging pathogens. She also recently led the work in identifying occult hepatitis B infections as a blood transfusion risk in England and has done pioneering work to investigate pre-exposure prophylaxis use among syphilis infected blood donors. While these activieis continue, she is currently establishing her research group at the University of Turku.
Prof Harvala is widely published in the field of medical, transfusion and public health virology (over 130 peer reviewed publications, h-index 48). She is an executive committee member of European Society for Clinical Virology and the programme committee member for the European Society for Clinical Microbiology and infectious Diseases. She was recently appointed to the WHO European Region Commission for the Certification of Poliomyelitis Eradication, and previously chaired the WHO R&D Blueprint group on Picornaviruses, the Microbiology Specialist Interest Group for the British Blood Transfusion Society, the Panel of Senior Virology Examiners for the RCPath and the Standing Advisory Committee for Transfusion Transmitted Infections.
She is currently involved in the undergraduate teaching of medical and biomedical students, being responsible for the virology part of that. She has previously been involved in the Undergraduate teaching at the University College of London, University of Edinburgh, the University of Oulu and at the University of Turku. She is also actively engaging with Postgraduate teaching by supervising both PhD and MSc students, and has undertaken PhD Supervisors training at the University of Oxford. Furthermore, she has extensive experience in Clinical Virology specialty training; she has been trained educational supervisor in Clinical Virology since 2016 and trained Royal College of Pathologist Examiner in Clinical Virology since 2017.
Her interest includes developing training further and as an example, she developed a new three-day module in Phylogenetics and Bioinformatics for European Centre for Disease Control (ECDC) Stockholm with the microbiological cases studies in 2016. Subsequently, she led the developing and delivering this for the ECDC summer schools in Stockholm, 2016 and 2017, and for the ECDC EPIET/EUPHEM fellows in Berlin, 2017 and 2018.
- Variability and pathogenicity of hepatitis E virus genotype 3 variants (2015)
- Journal of General Virology
- Acute viral hepatitis - should the current screening strategy be modified? (2014)
- Journal of Clinical Virology
() - Atypical hand, foot, and mouth disease associated with coxsackievirus A6 infection, Edinburgh, United Kingdom, January to February 2014. (2014)
- Eurosurveillance
- Burden of influenza B virus infections in Scotland in 2012/13 and epidemiological investigations between 2000 and 2012. (2014)
- Eurosurveillance
- Co-circulation of enteroviruses between apes and humans (2014)
- Journal of General Virology
- Comparison of diagnostic clinical samples and environmental sampling for enterovirus and parechovirus surveillance in Scotland, 2010 to 2012. (2014)
- Eurosurveillance
- Distinct systemic and central nervous system disease patterns in enterovirus and parechovirus infected children (2014)
- Journal of Infection
- High rates of infection with novel enterovirus variants in wild populations of mandrills and other old world monkey species (2014)
- Journal of Virology
- High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy (2013)
- Journal of Medical Virology
- Development and Assay of RNA Transcripts of Enterovirus Species A to D, Rhinovirus Species A to C, and Human Parechovirus: Assessment of Assay Sensitivity and Specificity of Real-Time Screening and Typing Methods (2012)
- Journal of Clinical Microbiology
(A1 Refereed original research article in a scientific journal) - Epidemiology and clinical characteristics of parainfluenza virus 3 outbreak in a Haemato-oncology unit (2012)
- Journal of Infection
- High detection frequency and viral loads of human rhinovirus species A to C in fecal samples; diagnostic and clinical implications (2012)
- Journal of Medical Virology
- High seroprevalence of enterovirus infections in apes and old world monkeys (2012)
- Emerging Infectious Diseases
- Comparison of human parechovirus and enterovirus detection frequencies in cerebrospinal fluid samples collected over a 5-year period in edinburgh: HPeV type 3 identified as the most common picornavirus type (2011)
- Journal of Medical Virology
- Detection and genetic characterization of enteroviruses circulating among wild populations of chimpanzees in Cameroon: relationship with human and simian enteroviruses (2011)
- Journal of Virology
- Disease burden of the most commonly detected respiratory viruses in hospitalized patients calculated using the disability adjusted life year (DALY) model (2011)
- Journal of Clinical Virology
- Rapid simultaneous detection of enterovirus and parechovirus RNAs in clinical samples by one-step real-time reverse transcription-PCR assay (2011)
- Journal of Clinical Microbiology
- Evolutionary Dynamics and Temporal/Geographical Correlates of Recombination in the Human Enterovirus Echovirus Types 9, 11, and 30 (2010)
- Journal of Virology
(A1 Refereed original research article in a scientific journal) - Parechoviruses in children: understanding a new infection (2010)
- Current Opinion in Infectious Diseases
- Recombination dynamics of human parechoviruses: investigation of type-specific differences in frequency and epidemiological correlates (2010)
- Journal of General Virology