Shruti Jain
Postdoctoral researcher
shrjai@utu.fi +358 29 450 4599 +358 50 573 8984 Kiinamyllynkatu 10 Turku : https://orcid.org/0000-0003-0748-6050 |
Diagnostics; immunoassays; point-of-care testing; assay optimization; clinical validation; clinical verification; analytical techniques; biomarkers; tumor markers; extracellular vesicle (EV) diagnostics; clinical chemistry; laboratory medicine; statistical analysis, SPSS, Origin, JMP, R programming; science communication
Early Cancer Diagnostics group, FICAN West Cancer Centre, InFLAMES Flagship
I am a Postdoctoral researcher in the Biotechnology unit at the Department of Life Technologies. My current research is on clinical biomarkers and epidemiological studies in lung cancer.
I have extensive experience in immunoassay development and optimization, along with verification and clinical validation studies. I have also done extensive data analysis and am experienced with using R programming, SPSS, Origin, JMP. I also have some knowledge regarding regulatory considerations.
Cancer is largely asymptomatic in early stages and the mortality increases with late detection. I look at glycosylation changes in cancer to identify new biomarkers that can be used as diagnostic targets. We have a highly sensitive and fluorescent nanoparticle based technology that we use to develop diagnostic assays for early cancer detection. I have developed an ovarian cancer diagnostic test that shows improved performance in postmenopausal women and in early stage cases compared to conventional assays. This test is now in the commercialization phase with a local diagnostic Turku based company. My current research as a postdoc includes identifying novel biomarkers for lung cancer diagnosis, that we are now in the process of patenting.
- MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025)
- Scientific Reports
- In the Company of Giants: GYSS 2024 and the Nobel Laureate Experience (2024)
- InFLAMES Flagship Blog
- Novel circulatory biomarkers for ovarian cancer diagnosis: Nanoparticle based glycovariant assays (2024) Jain, Shruti
- Aberrant glycosylation of α3 integrins as diagnostic markers in epithelial ovarian cancer (2023)
- Clinica Chimica Acta
- Diagnostic potential of nanoparticle aided assays for MUC16 and MUC1 glycovariants in ovarian cancer (2022)
- International Journal of Cancer
- A longitudinal analysis of CA125 glycoforms in the monitoring and follow up of high grade serous ovarian cancer (2020)
- Gynecologic Oncology