PhD James Conway - UTU Research Portal

James Conway
PhD

- Docent,
Department of Life Technologies (Faculty of Technology)

james.conway@utu.fi

: 4119

: https://orcid.org/0000-0003-3787-277X

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SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers (2024)
- Nature Communications
Lilja, Johanna; Kaivola, Jasmin; Conway, James R. W.; Vuorio, Joni; Parkkola, Hanna; Roivas, Pekka; Dibus, Michal; Chastney, Megan R.; Varila, Taru; Jacquemet, Guillaume; Peuhu, Emilia; Wang, Emily; Pentikäinen, Ulla; Posada, Itziar Martinez D.; Hamidi, Hellyeh; Najumudeen, Arafath K.; Sansom, Owen J.; Barsukov, Igor L.; Abankwa, Daniel; Vattulainen, Ilpo; Salmi, Marko; Ivaska, Johanna
Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling (2023)
- Proceedings of the National Academy of Sciences of the United States of America
Conway James R.W., Isomursu Aleksi, Follain Gautier, Härmä Ville, Jou-Ollé Eva, Pasquier Nicolas, Välimäki Eetu P.O., Rantala Juha K., Ivaska Johanna
IGFBP2 secretion by mammary adipocytes limits breast cancer invasion (2023)
- Science Advances
Conway James RW, Dinc Defne D, Follain Gautier, Paavolainen Oona, Kaivola Jasmin, Boström Pia, Hartiala Pauliina, Peuhu Emilia, Ivaska Johanna
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse (2023)
- Science Advances
Conway James R.W., Warren Sean C., Lee Young-Kyung, Mcculloch Andrew T., Magenau Astrid, Lee Victoria, Metcalf Xanthe L., Stoehr Janett, Haigh Katharina, Abdulkhalek Lea, Guaman Cristian S., Reed Daniel A., Murphy Kendelle J., Pereira Brooke A., Mélénec Pauline, Chambers Cecilia, Latham Sharissa L., Lenthall Helen, Deenick Elissa K., Ma Yuanqing, Phan Tri, Lim Elgene, Joshua Anthony M., Walters Stacey, Grey Shane T., Shi Yan-Chuan, Zhang Lei, Herzog Herbert, Croucher David R., Philp Andy, Scheele Colinda L.G.J., Herrmann David, Sansom Owen J., Morton Jennifer P., Papa Antonella, Haigh Jody J., Nobis Max, Timpson Paul
Publisher Correction: Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis (vol 23, pg 1073, 2021) (2022)
- Nature Cell Biology
Moreno-Layseca Paulina, Jäntti Niklas Z., Godbole Rashmi, Sommer Christian, Jacquemet Guillaume, Al-Akhrass Hussein, Conway James R. W., Kronqvist Pauliina, Kallionpää Roosa E., Oliveira-Ferrer Leticia, Cervero Pasquale, Linder Stefan, Aepfelbacher Martin, Zauber Henrik, Rae James, Parton Robert G., Disanza Andrea, Scita Giorgio, Mayor Satyajit, Selbach Matthias, Veltel Stefan, Ivaska Johanna
TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines (2022)
- Nature Methods
Ershov Dmitry, Phan Minh-Son, Pylvänäinen Joanna W., Rigaud Stephane U., Le Blanc Laure, Charles-Orszag Arthur, Conway James R.W., Laine Romain F., Roy Nathan H., Bonazzi Daria, Dumenil Guillaume, Jacquemet Guillaume, Tinevez Jean-Yves
A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance (2021)
- Oncogene
Al-Akhrass Hussein, Conway James RW, Poulsen Annemarie Svane Aavild, Paatero Ilkka, Kaivola Jasmin, Padzik Artur, Andersen Olav M, Ivaska Johanna
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis (2021)
- Nature Cell Biology
Moreno-Layseca Paulina, Jäntti Niklas Z, Godbole Rashmi, Sommer Christian, Jacquemet Guillaume, Al-Akhrass Hussein, Conway James RW, Kronqvist Pauliina, Kallionpää Roosa E, Oliveira-Ferrer Leticia, Cervero Pasquale, Linder Stefan, Aepfelbacher Martin, Zauber Henrik, Rae James, Parton Robert G, Disanza Andrea, Scita Giorgio, Mayor Satyajit, Selbach Matthias, Veltel Stefan, Ivaska Johanna
Integrin adhesion complexes (2021)
- Current Biology
Chastney Megan R., Conway James R. W., Ivaska Johanna
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status (2021)
- Science Advances
Murphy Kendelle J., Reed Daniel A., Vennin Claire, Conway James R. W., Nobis Max, Yin Julia X., Chambers Cecilia R., Pereira Brooke A., Lee Victoria, Filipe Elysse C., Trpceski Michael, Ritchie Shona, Lucas Morghan C., Warren Sean C., Skhinas Joanna N., Magenau Astrid, Metcalf Xanthe L., Stoehr Janett, Major Gretel, Parkin Ashleigh, Bidanel Romain, Lyons Ruth J., Zaratzian Anaiis, Tayao Michael, Da Silva Andrew, Abdulkhalek Lea, Gill Anthony J., Johns Amber L., Biankin Andrew V, Samra Jaswinder, Grimmond Sean M., Chou Angela, Goetz Jacky G., Samuel Michael S., Lyons J. Guy, Burgess Andrew, Caldon C. Elizabeth, Horvath Lisa G., Daly Roger J., Gadegaard Nikolaj, Wang Yingxiao, Sansom Owen J., Morton Jennifer P., Cox Thomas R., Pajic Marina, Herrmann David, Timpson Paul
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype (2021) Valdés-Mora Fátima, Salomon Robert, Gloss Brian Stewart, Law Andrew Man Kit, Venhuizen Jeron, Castillo Lesley, Murphy Kendelle Joan, Magenau Astrid, Papanicolaou Michael, Rodriguez de la Fuente Laura, Roden Daniel Lee, Colino-Sanguino Yolanda, Kikhtyak Zoya, Farbehi Nona, Conway James Ronald William, Sikta Neblina, Oakes Samantha Richelle, Cox Thomas Robert, O’Donoghue Seán Ignatius, Timpson Paul, Ormandy Christopher John, Gallego-Ortega David
Kinase-Independent Functions of MASTL in Cancer: A New Perspective on MASTL Targeting (2020)
- Cells
James Ronald William Conway, Elisa Närvä, Maria Emilia Taskinen, Johanna Ivaska
MASTL promotes cell contractility and motility through kinase-independent signaling (2020)
- Journal of Cell Biology
Maria Emilia Taskinen, Elisa Narv, James R.W. Conway, Laura Soto Hinojosa, Sergio Lilla, Anja Mai, Nicola De Franceschi, Laura L. Elo, Robert Grosse, Sara Zanivan, Jim C. Norman, Johanna Ivaska
Cell matrix adhesion in cell migration (2019)
- Essays in Biochemistry
Conway JRW, Jacquemet G
Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine (2018)
- Gut
Conway JR, Herrmann D, Evans TJ, Morton JP, Timpson P
Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism (2018)
- Cell Metabolism
Lancaster GI, Langley KG, Berglund NA, Kammoun HL, Reibe S, Estevez E, Weir J, Mellett NA, Pernes G, Conway JRW, Lee MKS, Timpson P, Murphy AJ, Masters SL, Gerondakis S, Kaczorowski DC, Bartonicek N, Meikle PJ, Dinger ME, Febbraio MA, Bond PJ
Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer (2018)
- Cell Reports
Conway JRW, Warren SC, Herrmann D, Murphy KJ, Cazet AS, Vennin C, Shearer RF, Killen MJ, Magenau A, Mélénec P, Pinese M, Nobis M, Zaratzian A, Boulghourjian A, Da Silva AM, Adam ASA, Del Monte-Nieto G, Haigh JJ, Harvey RP, Croucher DR, Wang Y, Pajic M, Sansom OJ, Morton JP, Caldon CE, Timpson P
MASTL overexpression promotes chromosome instability and metastasis in breast cancer (2018)
- Oncogene
Rogers S, McCloy RA, Parker BL, Gallego-Ortega D, Law AMK, Chin VT, Conway JRW, Fey D, Millar EKA, O'Toole S, Deng NT, Swarbrick A, Chastain PD, Cesare AJ, Timpson P, Caldon CE, Croucher DR, James DE, Watkins DN, Burgess A
Removing physiological motion from intravital and clinical functional imaging data (2018)
- eLife
Warren SC, Nobis M, Magenau A, Mohammed YH, Herrmann D, Moran I, Vennin C, Conway JRW, Melenec P, Cox TR, Wang YX, Morton JP, Welch HCE, Strathdee D, Anderson KI, Phan TG, Roberts MS, Timpson P
Annexin A6-A multifunctional scaffold in cell motility (2017)
- Cell Adhesion and Migration
Grewal T, Hoque M, Conway JRW, Reverter M, Wahba M, Beevi SS, Timpson P, Enrich C, Rentero C