Kiira Kalke - UTU Research Portal

Kiira Kalke

Institute of Biomedicine (Faculty of Medicine)

kiira.m.kalke@utu.fi

: https://orcid.org/0000-0002-7832-2021

Decorin Expressed From Herpes Simplex Virus Vector Improves Oncolytic Efficacy in Lung Adenocarcinoma Cells (2025)
- Proteoglycan Research
Frejborg, Fanny; Palomäki, Jussi; Kalke, Kiira; Orpana, Julius; Koivisto, Oliver; Paavilainen, Henrik; Rosenholm, Jessica M.; Zhang, Hongbo; Hukkanen, Veijo; Järveläinen, Hannu
Antiviral modified siRNA swarms for treatment of herpes simplex virus infection (2023) Kalke Kiira
Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy (2023)
- Microorganisms
Palomäki Jussi, Kalke Kiira, Orpana Julius, Lund Liisa, Frejborg Fanny, Paavilainen Henrik, Järveläinen Hannu, Hukkanen Veijo
Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV-1 (2023)
- Smart medicine
Lasanen Tuomas, Frejborg Fanny, Lund Liisa M., Nyman Marie C., Orpana Julius, Habib Huda, Alaollitervo Salla, Levanova Alesia A., Poranen Minna M., Hukkanen Veijo, Kalke Kiira
Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation (2022)
- Pharmaceuticals
Levanova Alesia A, Lampi Mirka, Kalke Kiira, Hukkanen Veijo, Poranen Minna M, Eskelin Katri
Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells (2022)
- PLoS Pathogens
Kalke Kiira, Lund Liisa M., Nyman Marie C., Levanova Alesia A., Urtti Arto, Poranen Minna M., Hukkanen Veijo, Paavilainen Henrik
The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1 (2022)
- Viruses
Kalke Kiira, Orpana Julius, Lasanen Tuomas, Esparta Olaya, Lund Liisa M., Frejborg Fanny, Vuorinen Tytti, Paavilainen Henrik, Hukkanen Veijo
Enzymatically synthesized 2 '-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity (2020)
- Antiviral Research
Levanova Alesia A., Kalke Kiira M., Lund Liisa M., Sipari Nina, Sadeghi Mohammadreza, Nyman Marie C., Paavilainen Henrik, Hukkanen Veijo, Poranen Minna M.
Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity (2020)
- Viruses
Kalke K, Lehtinen J, Gnjatovic J, Lund LM, Nyman MC, Paavilainen H, Orpana J, Lasanen T, Frejborg F, Levanova AA, Vuorinen T, Poranen MM, Hukkanen V