Antoine Stier
PhD
Ecophysiology; Ageing; Metabolism; Birds
I conducted my PhD in Ecophysiology at the
University of Strasbourg
(2010-2013), working on the relationships between mitochondrial function, oxidative stress and animal life histories.
As a side-project of my PhD, I demonstrated that avian
red blood cells possess functional mitochondria (Stier et al. 2013 Front. Zool.). Building
on this finding, I developed collaborations with the French Polar Institute
(2013-14) and the University of Aberdeen to use avian red blood cells to
study mitochondrial function in non-model and wild animals. I then moved to the University of Angers for a Research and Teaching position (2014-2015), where I was in charge of teaching Animal
Biology and Ecology. I developed a research project linking environmental
constraints to accelerated ageing in a reptile species.
I was then able to secure a Marie Curie fellowship (2016-17) to work as a Research Fellow at
the University of Glasgow on the impact of pre-natal environmental
conditions on ageing rate, using Japanese quail as a model species.
I moved to the University
of Turku in 2018 where I work as a TCSM Research Fellow (2018-2021). I am investigating the importance
of early-life hormonal exposure (stress and thyroid hormones) in determining
mitochondrial function and telomere dynamics during development and later in
life, using wild birds (king penguin and passerine
species).
My research is at the
crossroad between physiology, ecology and gerontology. I am broadly interested
in the physiological mechanisms contributing to the ageing process and their
implication in shaping organism’s phenotype from the conception to the death. My
research focus on the contribution of mitochondrial function, oxidative stress,
stress hormones and telomere dynamics as proximate mechanisms shaping health,
ageing and life histories. I use mainly bird species as models, both in
captivity and in their natural environment
2019: Supervision of Coline Marciau (Pre-PhD funding, University of Turku)
2019: Supervision of two MSc
student projects (University of Turku,
Finland)
2017-2020: PhD co-supervision of Tiia
Kärkkäinen (University of Turku)
of two BSc student projects (University of Turku,
Finland)
lecture in Animal Physiology (3rd BSc
year, University of Glasgow, UK)
of two MSc and one BSc student projects (University of Glasgow, UK)
in Zoology, Ecology and Behavioural Ecology and (100 contact hours: 1st BSc year, 2nd BSc
year, 1st MSc year, University of Angers, France)
of two MSc student projects (University of
Angers, France)
of one PhD chapter (Universities of
Angers and Toulon, France)
in Zoology and Applied Ecology (90 contact hours:
1st BSc & MSc years, University of Angers)
course of Ecology and Lecture in Biodiversity (30 contact hours: 2nd BSc year, 2nd MSc
year, University of Strasbourg, France)
in Zoology and Behavioural Ecology (60 contact hours:
1st BSc & MSc years, University of Strasbourg, France)
of three MSc student projects (University of
Strasbourg, France)
in Behavioural Ecology (40 contact hours:
1st and 2nd MSc years, University of Strasbourg)
of two MSc student projects (University of Strasbourg,
France)
in Zoology and Ethology (60 contact hours: 1st and 2nd
BSc years, University of Strasbourg)
- Changes in body surface temperature reveal the thermal challenge associated with catastrophic moult in captive Gentoo penguins (2024)
- Journal of Experimental Biology
(A1 Refereed original research article in a scientific journal) - Mitonuclear interactions impact aerobic metabolism in hybrids and may explain mitonuclear discordance in young, naturally hybridizing bird lineages (2024)
- Molecular Ecology
(A1 Refereed original research article in a scientific journal) - Oxygen release from hemoglobin has limited effects on mitochondrial respiration measured from red blood cells Reply to the Comment on "Increased retention of functional mitochondria in mature sickle red blood cells is associated with increased sickling tendency, hemolysis and oxidative stress" (2024)
- Haematologica
(B1 Non-refereed article in a scientific journal) - Social, not genetic, programming of development and stress physiology of a colonial seabird (2024)
- Proceedings of the Royal Society B: Biological Sciences
(A1 Refereed original research article in a scientific journal) - Surface temperatures are influenced by handling stress independently of corticosterone levels in wild king penguins (Aptenodytes patagonicus) (2024)
- Journal of Thermal Biology
(A1 Refereed original research article in a scientific journal) - Dietary nucleotides can prevent glucocorticoid-induced telomere attrition in a fast-growing wild vertebrate (2023)
- Molecular Ecology
(A1 Refereed original research article in a scientific journal) - Early-life environmental effects on mitochondrial aerobic metabolism: a brood size manipulation in wild great tits (2023)
- Journal of Experimental Biology
(A1 Refereed original research article in a scientific journal) - From maternal glucocorticoid and thyroid hormones to epigenetic regulation of offspring gene expression: An experimental study in a wild bird species (2023)
- Evolutionary Applications
(A1 Refereed original research article in a scientific journal) - No evidence for associations between brood size, gut microbiome diversity and survival in great tit (Parus major) nestlings (2023)
- Animal microbiome
(A1 Refereed original research article in a scientific journal) - Prenatal thyroid hormones accelerate postnatal growth and telomere shortening in wild great tits (2023)
- Journal of Experimental Biology
(A1 Refereed original research article in a scientific journal) - Sharing your snack: Unusual observation of a chick-chick feeding occurrence in colonial king penguin (Aptenodytes patagonicus) (2023)
- Behaviour
(A1 Refereed original research article in a scientific journal) - Altricial Bird Early-Stage Embryos Express the Molecular "Machinery" to Respond to and Modulate Maternal Thyroid Hormone Cues (2022)
- Physiological and Biochemical Zoology
(A1 Refereed original research article in a scientific journal) - Does IGF-1 Shape Life-History Trade-Offs? Opposite Associations of IGF-1 With Telomere Length and Body Size in a Free-Living Bird (2022)
- Frontiers in Ecology and Evolution
(A1 Refereed original research article in a scientific journal) - Effect of prenatal glucocorticoids and thyroid hormones on developmental plasticity of mitochondrial aerobic metabolism, growth and survival: an experimental test in wild great tits (2022)
- Journal of Experimental Biology
(A1 Refereed original research article in a scientific journal) - Experimental demonstration of prenatal programming of mitochondrial aerobic metabolism lasting until adulthood (2022)
- Proceedings of the Royal Society B: Biological Sciences
(A1 Refereed original research article in a scientific journal) - Population differences in the length and early-life dynamics of telomeres among European pied flycatchers (2022)
- Molecular Ecology
(A1 Refereed original research article in a scientific journal) - Within-individual repeatability in telomere length: A meta-analysis in nonmammalian vertebrates (2022)
- Molecular Ecology
(A1 Refereed original research article in a scientific journal) - Author Correction: Testing for context-dependent effects of prenatal thyroid hormones on offspring survival and physiology: an experimental temperature manipulation (Scientific Reports, (2020), 10, 1, (14563), 10.1038/s41598-020-71511-y) (2021)
- Scientific Reports
(Other publication) - Effects of Heat Waves During Post-natal Development on Mitochondrial and Whole Body Physiology: An Experimental Study in Zebra Finches (2021)
- Frontiers in Physiology
(A1 Refereed original research article in a scientific journal) - Human blood contains circulating cell-free mitochondria, but are they really functional? (2021)
- American Journal of Physiology : Endocrinology and Metabolism
(B1 Non-refereed article in a scientific journal)