Partho Sen
PhD in Biological Sciences
Systems Medicine partho.sen@utu.fi Tykistökatu 6 Turku ORCID identifier: https://orcid.org/0000-0003-0475-2763 |
Areas of expertise
Research Interests & Expertise: Systems biology, Bioinformatics and Metabolic Modelling applied to the human gut microbiota. Particularly interested in Metabolomics, Pathway analysis, Transcriptomics, Metagenomics. Extended interest in mathematical modeling and integration of X-OMIC datasets, computational method/algorithm development.
Research Interests & Expertise: Systems biology, Bioinformatics and Metabolic Modelling applied to the human gut microbiota. Particularly interested in Metabolomics, Pathway analysis, Transcriptomics, Metagenomics. Extended interest in mathematical modeling and integration of X-OMIC datasets, computational method/algorithm development.
Biography
Sen is an expert in bioinformatics and computational systems biology. He obtained PhD in 'Biological Sciences' from University of Montpellier2, France. He develops and applies best practices in computational biology by deploying mathematical modeling and machine learning techniques on x-omics (transcriptomics, metabolomics, metagenomics, etc.) datasets to study autoimmune and metabolic disease / disorders such as T1D, Celiac disease, Obesity and NAFLD in humans. Sen pursued his postdoctorate from Prof. Nielsen’s lab at Chalmers University of Technology, Gothenburg, Sweden. There, he was involved in several international and EU projects under the topics metabolomics / lipidomics and human metabolism.
Currently, he is working as a senior postdoctoral researcher in the Systems Medicine group at Turku Bioscience, University of Turku, Finland, headed by Prof. Matej Oresic. He is involved in various cutting-edge projects which includes, modeling of immune cells and human gut microbiota in T1D and in NAFLD.
Sen is an expert in bioinformatics and computational systems biology. He obtained PhD in 'Biological Sciences' from University of Montpellier2, France. He develops and applies best practices in computational biology by deploying mathematical modeling and machine learning techniques on x-omics (transcriptomics, metabolomics, metagenomics, etc.) datasets to study autoimmune and metabolic disease / disorders such as T1D, Celiac disease, Obesity and NAFLD in humans. Sen pursued his postdoctorate from Prof. Nielsen’s lab at Chalmers University of Technology, Gothenburg, Sweden. There, he was involved in several international and EU projects under the topics metabolomics / lipidomics and human metabolism.
Currently, he is working as a senior postdoctoral researcher in the Systems Medicine group at Turku Bioscience, University of Turku, Finland, headed by Prof. Matej Oresic. He is involved in various cutting-edge projects which includes, modeling of immune cells and human gut microbiota in T1D and in NAFLD.
Publications 
1 of 2
- 1‐deoxyceramides – key players in lipotoxicity and progression to type 2 diabetes? (2021)
- Acta Physiologica
(B1 Journal article) - Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species (2021)
- Scientific Reports
(A1 Journal article – refereed) - Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations (2021)
- Metabolites
(A2 Review article in a scientific journal) - Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis (2020)
- Schizophrenia Bulletin
(A1 Journal article – refereed) - Deep learning meets metabolomics: a methodological perspective (2020)
- Briefings in Bioinformatics
(A2 Review article in a scientific journal) - Dysregulated lipid metabolism precedes onset of psychosis (2020)
- Biological Psychiatry
(A1 Journal article – refereed) - Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease (2020)
- Environmental Research
(A1 Journal article – refereed) - Metabolic alterations in immune cells associate with progression to type 1 diabetes (2020)
- Diabetologia
(A1 Journal article – refereed) - Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes (2020)
- Environment International
(A1 Journal article – refereed) - Systems biology approaches to study lipidomes in health and disease (2020)
- Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
(A2 Review article in a scientific journal) - Metabolic Modeling of Human Gut Microbiota on a Genome Scale: An Overview (2019)
- Metabolites
(A2 Review article in a scientific journal) - Metabolic profiling and compound-class identification reveal alterations in serum triglyceride levels in mice immunized with human vaccine adjuvant Alum (2019) Sakda Khoomrung, Intawat Nookaew, Partho Sen, Thorunn A Olafsdottir, Josefine Persson, Thomas Moritz, Peter Andersen, Ali M Harandi, Jens Nielsen
(A1 Journal article – refereed) - Persistent Alterations in Plasma Lipid Profiles Before Introduction of Gluten in the Diet Associated With Progression to Celiac Disease (2019)
- Clinical and Translational Gastroenterology
(A1 Journal article – refereed) - The Role of Omic Technologies in the Study of the Human Gut Microbiome (2019) Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
(A3 Book chapter) - An Overview of Metabolomics Data Analysis: Current Tools and Future Perspectives (2018) Comprehensive Analytical Chemistry Lamichhane S., Sen P., Dickens A., Hyötyläinen T., Orešič M.
(B2 Book chapter) - Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe (2018)
- Methods
(A1 Journal article – refereed) - Perspectives on systems modeling of human peripheral blood mononuclear cells (2018)
- Frontiers in Molecular Biosciences
(A2 Review article in a scientific journal) - Evaluation and assessment of read-mapping by multiple next-generation sequencing aligners based on genome-wide characteristics (2017)
- Genomics
(A1 Journal article – refereed) - Herring and chicken/pork meals lead to differences in plasma levels of TCA intermediates and arginine metabolites in overweight and obese men and women (2017)
- Molecular Nutrition and Food Research
(A1 Journal article – refereed) - Selection of complementary foods based on optimal nutritional values (2017)
- Scientific Reports
(A1 Journal article – refereed)
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