Hannu Aro
Professor
hannu.aro@utu.fi +358 40 353 7644 Hämeentie 11 Turku |
Orthopaedic Surgery; Hip replacement; Osteoporosis; Radiostereometric analysis of joint implant healing; PET imaging of infections
I am an academic Orthopaedic Surgeon with the clinical license both in Finland and in USA. I have a strong basic science background on the biomechanics and molecular biology of bone healing as well as on biomaterial incorporation with bone. I have supervised 15 PhD theses on these subjects and I have more than 170 original publications. During the past 15 years in collaboration with leading international companies and Finnish start-up companies, I have focused on the randomized phase I-IV clinical trials on fracture patients and hip replacement patients, applying advanced imaging technology (RSA, radiostereometric analysis). In everyday clinical practice, I am nowadays focused on bone tumor surgery and hip/knee replacements. Among University duties, I am in charge of the resident program in orthopaedic surgery and traumatology.
Currently, my main clinical research interest is in osteoporosis and prevention of periprosthetic fractures in postmenopausal women and in replacement of human allogeneic bone grafts by bioresorbable synthetic substitutes. In addition, we have had an interest in the development of PET/CT imaging technology for detection of indolent periprosthetic infections.
Orthopaedic Surgery and Traumatology; Resident Education
- PET/CT to detect adverse reactions to metal debris in patients with metal-on-metal hip arthroplasty: an exploratory prospective study (2018)
- Clinical Physiology and Functional Imaging
- CORR Insights (R): The Effect of Surgical Technique and Spacer Texture on Bone Regeneration: A Caprine Study Using the Masquelet Technique (2017)
- Clinical Orthopaedics and Related Research
- Denosumabin vaikutus periproteettiseen luukatoon ja lonkkaproteesin kiinnittymiseen postmenopausaalisilla naisilla : satunnaistettu, kaksoissokkoutettu, lumekontrolloitu kliininen tutkimus (2017)
- Suomen ortopedia ja traumatologia
- Intensity of F-18-FDG PET Uptake in Culture-Negative and Culture-Positive Cases of Chronic Osteomyelitis (2017)
- Contrast Media and Molecular Imaging
- Increased migration of uncemented acetabular cups in female total hip arthroplasty patients with low systemic bone mineral density. (2016)
- Acta Orthopaedica
- In vitro osteogenic capacity of bone marrow MSCs from postmenopausal women reflect the osseointegration of their cementless hip stems (2016)
- Bone Reports
- Is Model-based Radiostereometric Analysis Suitable for Clinical Trials of a Cementless Tapered Wedge Femoral Stem? (2016)
- Clinical Orthopaedics and Related Research
- Enhanced osteoblastic differentiation and bone formation in co-culture of human bone marrow mesenchymal stromal cells and peripheral blood mononuclear cells with exogenous VEGF (2015)
- Orthopaedics and Traumatology: Surgery and Research
- Local delivery of a selective androgen receptor modulator failed as an anabolic agent in a rat bone marrow ablation model (2015)
- Acta Orthopaedica
- (68)Ga-DOTA-Siglec-9 PET/CT imaging of peri-implant tissue responses and staphylococcal infections (2014)
- EJNMMI Research
- 68Ga-DOTA-Siglec-9 PET imaging detects biomaterial infection caused by S. epidermidis (2014)
- Bone and Joint Journal
- Adherence of hip and knee arthroplasty studies to RSA standardization guidelines. A systematic review. (2014)
- Acta Orthopaedica
- Mechanical properties and in vivo performance of load-bearing fiber-reinforced composite intramedullary nails with improved torsional strength (2014)
- Journal of the Mechanical Behavior of Biomedical Materials
- Osteointegration of PLGA implants with nanostructured or microsized β-TCP particles in a minipig model (2014)
- Journal of the Mechanical Behavior of Biomedical Materials
- Analysis of Trabecular Bone Microstructure Using Contour Tree Connectivity (2013)
- Lecture Notes in Computer Science
- Biological responses of silver-coated thermosets: an in vitro and in vivo study (2013)
- Acta Biomaterialia
- Characterization of porous glass fiber-reinforced composite (FRC) implant structures: porosity and mechanical properties (2013)
- Journal of Materials Science: Materials in Medicine
- Quantitative characterization of porous commercial and experimental bone graft substitutes with microcomputed tomography. (2013)
- Journal of Biomedical Materials Research Part B: Applied Biomaterials
- A comparative 18F-FDG PET/CT imaging of experimental Staphylococcus aureus osteomyelitis and Staphylococcus epidermidis foreign-body-associated infection in the rabbit tibia. (2012)
- EJNMMI Research
- A Controlled Register-Based Study of 460 Neurofibromatosis 1 Patients: Increased Fracture Risk in Children and Adults Over 41 Years of Age (2012)
- Journal of Bone and Mineral Research