MD, PhD, Professor Emeritus Mika Scheinin - UTU Research Portal

Mika Scheinin
MD, PhD, Professor Emeritus

Institute of Biomedicine (Faculty of Medicine)

mschein@utu.fi

ORCID identifier: https://orcid.org/0000-0001-7579-9126

Areas of expertise

Bioanalytics; Clinical Pharmacology; Drug Development; Positron Emission Tomography; Research Ethics

Publications

12 of 13

Influence of MK-467, a peripherally acting α2-adrenoceptor antagonist on the disposition of intravenous dexmedetomidine in dogs. (2012)
- Drug Metabolism and Disposition
Honkavaara Juhani, Restitutti Flavia, Raekallio Marja, Salla Kati, Kuusela Erja, Ranta-Panula Ville, Rinne Valtteri, Vainio Outi, Scheinin Mika
(A1 Refereed original research article in a scientific journal)
Involvement of α2-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia. (2012)
- Neuroendocrinology
Ruohonen ST, Ruohonen S, Gilsbach R, Savontaus E, Scheinin M, Hein L
(A1 Refereed original research article in a scientific journal)
Lääkeaineiden vaikutusmekanismit: reseptorit (2012) Farmakologia ja toksikologia Scheinin Mika
(A3 Refereed book chapter or chapter in a compilation book)
Might the observed α2A-adrenoceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? (2012)
- Bioorganic and Medicinal Chemistry
Diamanti Eleonora, Del Bello Fabio, Carbonara Giuseppe, Carrieri Antonio, Fracchiolla Giuseppe, Giannella Mario, Mammoli Valerio, Piergentili Alessandro, Pohjanoksa Katariina, Quaglia Wilma, Scheinin Mika, Pigini Maria
(A1 Refereed original research article in a scientific journal)
Pharmacokinetics of [F-18]flutemetamol in wild-type rodents and its binding to beta amyloid deposits in a mouse model of Alzheimer's disease (2012)
- European Journal of Nuclear Medicine and Molecular Imaging
Snellman A, Rokka J, Lopez-Picon FR, Eskola O, Wilson I, Farrar G, Scheinin M, Solin O, Rinne JO, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Synthesis and biological activities of 2- [(heteroaryl)methyl]imidazolines (2012)
- Bioorganic and Medicinal Chemistry
Saczewski Jaroslaw, Hudson Alan, Scheinin Mika, Rybcynska Apolonia, Ma Daqing, Saczewski Franciszek, Laird Shayna, Laurila Jonne M, Boblewski Konrad, Lehmann Artur, Gu Jianteng, Watts Helena
(A1 Refereed original research article in a scientific journal)
Synthesis and biological activities of 2-[(heteroaryl)methyl]imidazolines (2012)
- Bioorganic and Medicinal Chemistry
Saczewski J, HUDSON A, SCHEININ M, RYBCZYNSKA A, MA DQ, SACZEWSKI F, LAIRD S, LAURILA JM, Boblewski K, LEHMANN A, GU JT, WATTS H
(A1 Refereed original research article in a scientific journal)
Tietoruutu L2. Lääkeaineiden sitoutuminen reseptoriin (2012) Farmakologia ja toksikologia Scheinin Mika
(A3 Refereed book chapter or chapter in a compilation book)
3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the ?2-adrenoceptor compared to the imidazoline I1 receptor (2011)
- Bioorganic and Medicinal Chemistry
Saczewski Franciszek, Kornicka Anita, Hudson Alan L, Laird Shayna, Scheinin Mika, Laurila Jonne M, Rybczynska Apolonia, Boblewski Konrad, Lehmann Artur, Gdaniec Maria
(A1 Refereed original research article in a scientific journal)
alpha(2)-Adrenoceptor Regulation of Blood Glucose Homeostasis (2011)
- Basic and Clinical Pharmacology and Toxicology. Supplement
Fagerholm V, Haaparanta M, Scheinin M
(A1 Refereed original research article in a scientific journal)
Dietary sodium modulates the interaction between efferent and afferent renal nerve activity by altering activation of α2-adrenoceptors on renal sensory nerves (2011)
- AJP - Regulatory, Integrative and Comparative Physiology
Kopp UC, Cicha MZ, Smith LA, Ruohonen S, Scheinin M, Fritz N, Hökfelt T
(A1 Refereed original research article in a scientific journal)
Different metabolic responses of human brown adipose tissue to activation by cold and insulin (2011)
- Cell Metabolism
Janne Orava, Pirjo Nuutila, Martin E Lidell, Vesa Oikonen, Tommi Noponen, Tapio Viljanen, Mika Scheinin, Markku Taittonen, Tarja Niemi, Sven Enerbäck, Kirsi A Virtanen
(A1 Refereed original research article in a scientific journal)
Dorsal hand vein responses to the α₁-adrenoceptor agonist phenylephrine do not predict responses to the α₂-adrenoceptor agonist dexmedetomidine. (2011)
- European Journal of Pharmacology
Posti JP, Valve L, Ruohonen S, Akkila J, Scheinin M, Snapir A
(A1 Refereed original research article in a scientific journal)
Genetic Variations in the ?2A-Adrenoreceptor Are Associated With Blood Pressure Response to the Agonist Dexmedetomidine (2011)
- Circulation: Cardiovascular Genetics
Kurnik Daniel, Muszkat Mordechai, Li Chun, Sofowora Gbenga G, Friedman Eitan A, Scheinin Mika, Wood Alastair J J, Stein C Michael
(A1 Refereed original research article in a scientific journal)
Involvement of the first transmembrane segment of human alpha(2)-adrenoceptors in the subtype-selective binding of chlorpromazine, spiperone and spiroxatrine (2011)
- British Journal of Pharmacology
Laurila JMM, Wissel G, Xhaard H, Ruuskanen JO, Johnson MS, Scheinin M
(A1 Refereed original research article in a scientific journal)
Kliinisten lääketutkimusten etiikka (2011) Kliininen farmakologia ja lääkehoito Scheinin Mika, Halila Ritva
(D2 Article in a professional compilation book)
Antinociceptive Synergism of MD-354 and Clonidine. Part II. The alpha(2)-Adrenoceptor Component (2010)
- Basic and Clinical Pharmacology and Toxicology. Supplement
Young S, Vainio M, Scheinin M, Dukat M
(A1 Refereed original research article in a scientific journal)
Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception (2010)
- European Journal of Pain
Kohli U, Muszkat M, Sofowora G G, Harris P A, Friedman E A, Dupont W D, Scheinin M, Wood A J, Stein C M, Kurnik D
(A1 Refereed original research article in a scientific journal)
Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report (2010)
- Journal of Medical Case Reports
Iirola T, Laitio R, Kentala E, Aantaa R, Kurvinen J-P, Scheinin M, Olkkola KT
(A1 Refereed original research article in a scientific journal)
Homogeneous GTP binding assay employing QRET technology (2010)
- Journal of Biomolecular Screening
Rozwandowicz-Jansen A, Laurila J, Martikkala E, Frang H, Hemmilä I, Scheinin M, Hänninen P, Härmä H
(A1 Refereed original research article in a scientific journal)