Mari Vähä-Mäkilä

- Senior Researcher,
- Research Coordinator
- Development Manager
Institute of Biomedicine (Faculty of Medicine)

mari.vaha-makila@utu.fi

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Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study (2017)
- Acta Diabetologica
Kohler M, Beyerlein A, Vehik K, Greven S, Umlauf N, Lernmark A, Hagopian WA, Rewers M, She JX, Toppari J, Akolkar B, Krischer JP, Bonifacio E, Ziegler AG; The TEDDY Study Group
Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study (2017)
- Diabetologia
Lonnrot M, Lynch KF, Larsson HE, Lernmark A, Rewers MJ, Torn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Hyoty H; on behalf of the TEDDY Study Group
The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study (2017)
- Developmental Psychobiology
Roth R, Baxter J, Vehik K, Hopkins D, Killian M, Gesualdo P, Melin J, Simell B, Strauss E, Lernmark A, Johnson SB; The TEDDY Study Group
Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study (2016)
- Diabetes
Helena Elding Larsson, Kendra Vehik, Michael J. Haller, Xiang Liu, Beena Akolkar, William Hagopian, Jeffrey Krischer, åke Lernmark, Jin-Xiong She, Olli Simell, Jorma Toppari, Anette-G. Ziegler, Marian Rewers; for the TEDDY Study Group
Imbalance of plasma amino acids, metabolites and lipids in patients with lysinuric protein intolerance (LPI) (2016)
- Metabolism
Kurko J, Tringham M, Tanner L, Nanto-Salonen K, Vaha-Makila M, Nygren H, Poho P, Lietzen N, Mattila I, Olkku A, Hyotylainen T, Oresic M, Simell O, Niinikoski H, Mykkanen J
Natural Development of Antibodies against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Protein Antigens during the First 13 Years of Life (2016)
- Clinical and Vaccine Immunology
Borges IC, Andrade DC, Cardoso MRA, Toppari J, Vaha-Makila M, Ilonen J, Knip M, Hyoty H, Veijola R, Simell O, Jartti T, Kayhty H, Ruuskanen O, Nascimento-Carvalho CM
Reduced β-cell function in early preclinical type 1 diabetes (2016)
- European Journal of Endocrinology
Koskinen MK, Helminen O, Matomäki J, Aspholm S, Mykkänen J, Mäkinen M, Simell V, Vähä-Mäkilä M, Simell T, Ilonen J, Knip M, Veijola R, Toppari J, Simell OG
The role of innate immunity in Type 1 Diabetes (T1D) (2016)
- Scandinavian Journal of Immunology
Vaha-Makila M, Hellman V, Mykkanen J, Paavanen-Huhtala S, Ronnemaa T, Simell O, Knip M, Ilonen J, Veijola R, Toppari J
Dysfunction in macrophage toll-like receptor signaling caused by an inborn error of cationic amino acid transport (2015)
- Molecular Immunology
Kurko J, Vähä-Mäkilä M, Tringham M, Tanner L, Paavanen-Huhtala S, Saarinen M, Näntö-Salonen K, Simell O, Niinikoski H, Mykkänen J
Serum Proteomes Distinguish Children Developing Type 1 Diabetes in a Cohort With HLA-Conferred Susceptibility (2015)
- Diabetes
Moulder R, Bhosale SD, Erkkila T, Laajala E, Salmi J, Nguyen EV, Kallionpaa H, Mykkanen J, Vaha-Makila M, Hyoty H, Veijola R, Ilonen J, Simell T, Toppari J, Knip M, Goodlett DR, Lahdesmaki H, Simell O, Lahesmaa R
Antibodies to Lactobacilli and Bifidobacteria in young children with different propensity to develop islet autoimmunity (2014)
- Journal of Immunology Research
Ija Talja, Anna-Liisa Kubo, Riitta Veijola, Mikael Knip, Olli Simell, Jorma Ilonen, Mari Vähä-Mäkilä, Epp Sepp, Marika Mikelsaar, Meeme Utt, Raivo Uibo
Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production (2008) Liljeroos M, Vuolteenaho R, Rounioja S, Henriques-Normark B, Hallman M, Ojaniemi M
TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice (2006) Ojaniemi M, Liljeroos M, Harju K, Sormunen R, Vuolteenaho R, Hallman M
Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages (2003) Ojaniemi M, Glumoff V, Harju K, Liljeroos M, Vuori K, Hallman M