MD, PhD Johannes Routila - UTU Research Portal

Johannes Routila
MD, PhD

- ,
Otorhinolaryngology - Head and Neck Surgery (Department of Clinical Medicine)
- Docent,
Department of Clinical Medicine (Faculty of Medicine)

johannes.routila@utu.fi

ORCID identifier: https://orcid.org/0000-0001-5385-7065

Areas of expertise

head and neck cancer; radioresistance; biomarkers; audiology; vestibulology; neuro-otology

Research

Dissertation focused on the use of biomarkers in head and neck cancer therapy selection with special focus on radio- and chemoradiosensitivity associated stemness-related biomarkers.

In addition, I have research interests covering the fields of audiology and neuro-otology.

Publications

1 of 4

Prognostic role of histological depth of invasion in T1-2 oropharyngeal squamous cell carcinoma (2026)
- American Journal of Otolaryngology
Nissi, Linda; Elseragy, Amr; Wahab, Awais; Wennerstrand, Pia; Knuutila, Maisa; Routila, Johannes; Huusko, Teemu; Irjala, Heikki; Salo, Tuula; Ventelä, Sami
(A1 Refereed original research article in a scientific journal)
Added value of HPV-DNA in situ hybridization as an adjunct to p16 Immunohistochemistry in oropharyngeal squamous cell carcinoma (2025)
- Acta Oto-Laryngologica
Nissi, Linda; Huusko, Teemu; Routila, Johannes; Vaittinen, Samuli; Leivo, Ilmo; Irjala, Heikki; Ventela, Sami
(A1 Refereed original research article in a scientific journal)
Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer (2025)
- Science Advances
Kauko, Otto; Turunen, Mikko; Pihlajamaa, Päivi; Häkkinen, Antti; Queiroz, Rayner M. L.; Pääkkönen, Mirva; Ventelä, Sami; Gaetani, Massimiliano; Lundström, Susanna L.; Murgia, Antonio; Sahu, Biswajyoti; Routila, Johannes; Wei, Gong-Hong; Irjala, Heikki; Griffin, Julian L.; Lilley, Kathryn S.; Kivioja, Teemu; Hautaniemi, Sampsa; Taipale, Jussi
(A1 Refereed original research article in a scientific journal)
Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma (2025)
- Cancer Medicine
Routila, Erica; Salminen, Sadie; Mahran, Randa; Toriseva, Mervi; Irjala, Heikki; Haapio, Eeva; Kytö, Eero; Ventelä, Sami; Pettersson, Kim; Routila, Johannes; Gidwani, Kamlesh; Leivo, Janne
(A1 Refereed original research article in a scientific journal)
Histological tumor necrosis predicts decreased survival after neoadjuvant chemotherapy in head and neck squamous cell carcinoma (2025)
- Oral Oncology
Koskenniemi, A.R.; Huusko, T.; Routila, J.; Jalkanen, S.; Hollmén, M.; Vainio, P.; Ventelä, S.
(A1 Refereed original research article in a scientific journal)
LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer (2025)
- Embo molecular medicine
Qiao, Xi; Routila, Johannes; Tienhaara, Mari; Irjala, Heikki; Santhi, Priyadharshini Parimelazhagan; Huusko, Teemu; Nissi, Linda; Paatero, Ilkka; Lehtinen, Noora; Rantala, Juha; Viljanen, Toni; Leivo, Ilmo; Koivunen, Petri; Jouppila-Matto, Anna; Taulu, Rami; Back, Leif; Wilkman, Tommy; Haapio, Eeva; Kinnunen, Ilpo; Kurppa, Kari; Westermarck, Jukka; Ventelä, Sami
(A1 Refereed original research article in a scientific journal)
Assessment of targeted therapy opportunities in sinonasal cancers using patient-derived functional tumor models (2024)
- Translational Oncology
Lehtinen, Noora; Suhonen, Janne; Rice, Kiesha; Välimäki, Eetu; Toriseva, Mervi; Routila, Johannes; Halme, Perttu; Rahi, Melissa; Irjala, Heikki; Leivo, Ilmo; Kallajoki, Markku; Nees, Matthias; Kuopio, Teijo; Ventelä, Sami; Rantala, Juha K.
(A1 Refereed original research article in a scientific journal)
Identification of stemness-related glycosylation changes in head and neck squamous cell carcinoma (2024)
- BMC Cancer
Routila, Erica; Mahran, Randa; Salminen, Seppo; Irjala, Heikki; Haapio, Eeva; Kytö, Eero; Ventelä, Sami; Petterson, Kim; Routila, Johannes; Gidwani, Kamlesh; Leivo, Janne
(A1 Refereed original research article in a scientific journal)
Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer (2024)
- Cell
Punovuori, Karolina; Bertillot, Fabien; Miroshnikova, Yekaterina A.; Binner, Mirjam I.; Myllymäki, Satu-Marja; Follain, Gautier; Kruse, Kai; Routila, Johannes; Huusko, Teemu; Pellinen, Teijo; Hagström, Jaana; Kedei, Noemi; Ventelä, Sami; Mäkitie, Antti; Ivaska, Johanna; Wickström, Sara A.
(A1 Refereed original research article in a scientific journal)
Vestibular Evoked Myogenic Potential (VEMP) -mittaukset (2024) XLIV Valtakunnalliset audiologian päivät ja Teknisen audiologian iltapäivä Routila, Johannes
(D3 Article in a professional conference publication)