PhD Riina Kaukonen - UTU Research Portal

Riina Kaukonen
PhD

Turku Bioscience Centre (Independent units)

riina.kaukonen@utu.fi

+358 29 450 3804

+358 50 564 0315

Tykistökatu 6

Turku

Areas of expertise

Genomics, epigenomics, single-cell genomics, next-generation sequencing, cancer,

Biography

Doctor of Philosophy, 2016
University of Turku, Faculty of Medicine
Department of Medical Biochemistry and Genetics
Turku Doctoral Programme of Molecular Med. TuDMM

Master of Science, 2012
University of Turku, Faculty of Mathematics and Natural Sciences, Department of Biology
Physiology and Genetics Track
Major subject: Physiology and Genetics

Bachelor of Science, 2010
University of Turku, Faculty of Mathematics and Natural Sciences, Department of Biology
Major subject: Physiology and Genetics

Publications

From maternal glucocorticoid and thyroid hormones to epigenetic regulation of offspring gene expression: An experimental study in a wild bird species (2023)
- Evolutionary Applications
Hukkanen Mikaela, Hsu Bin-Yan, Cossin-Sevrin Nina, Crombecque Mélanie, Delaunay Axelle, Hollmen Lotta, Kaukonen Riina, Konki Mikko, Lund Riikka, Marciau Coline, Stier Antoine, Ruuskanen Suvi
(A1 Refereed original research article in a scientific journal)
PIM kinases regulate early human Th17 cell differentiation (2023)
- Cell Reports
Buchacher Tanja, Shetty Ankitha, Koskela Saara A., Smolander Johannes, Kaukonen Riina, Sousa Antonio G. G., Junttila Sini, Laiho Asta, Rundquist Olof, Lonnberg Tapio, Marson Alexander, Rasool Omid, L. Laura, Lahesmaa Riitta
(A1 Refereed original research article in a scientific journal)
Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy (2021)
- Neurobiology of Stress
Lund Riikka, Kyläniemi Minna, Pettersson Nina, Kaukonen Riina, Konki Mikko, Scheinin Noora, Karlsson Linnea, Karlsson Hasse, Ekholm Eeva
(A1 Refereed original research article in a scientific journal)
Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression (2020)
- BMC Medical Genomics
Damien Kaukonen, Riina Kaukonen, Lélia Polit, Bryan T Hennessy, Riikka Lund, Stephen F Madden
(A1 Refereed original research article in a scientific journal)
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities (2020)
- Genome Medicine
Juha Mehtonen, Susanna Teppo, Mari Lahnalampi, Aleksi Kokko, Riina Kaukonen, Laura Oksa, Maria Bouvy-Liivrand, Alena Malyukova, Artturi Mäkinen, Saara Laukkanen, Petri I. Mäkinen, Samuli Rounioja, Pekka Ruusuvuori, Olle Sangfelt, Riikka Lund, Tapio Lönnberg, Olli Lohi, Merja Heinäniemi
(A1 Refereed original research article in a scientific journal)
Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils (2019)
- Immunity
Takeda A, Hollmén M, Dermadi D, Pan J, Brulois KF, Kaukonen R, Lönnberg T, Boström P, Koskivuo I, Irjala H, Miyasaka M, Salmi M, Butcher EC, Jalkanen S
(A1 Refereed original research article in a scientific journal)
Cell-derived matrices for studying cell proliferation and directional migration in a complex 3D microenvironment (2017)
- Nature Protocols
Kaukonen R, Jacquemet G, Hamidi H, Ivaska J
(A1 Refereed original research article in a scientific journal)
SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland (2017)
- EMBO Journal
Emilia Peuhu, Riina Kaukonen, Martina Lerche, Markku Saari, Camilo Guzmán, Pia Rantakari, Nicola De Franceschi, Anni Wärri, Maria Georgiadou, Guillaume Jacquemet, Elina Mattila, Reetta Virtakoivu, Yuming Liu, Youmna Attie, Kathleen A. Silva, Timo Betz, John P. Sundberg, Marko Salmi, Marie-Ange Deugnier, Kevin W. Eliceiri, and Johanna Ivaska
(A1 Refereed original research article in a scientific journal)
Filopodia and stromal extracellular matrix as regulators of cancer cell invasion and growth (2016) Kaukonen Riina
(G5 Article dissertation )
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription (2016)
- Nature Communications
Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventelä S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen P-L, Joensuu H, Grenman R, Ivaska J
(A1 Refereed original research article in a scientific journal)
Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function (2015)
- Cancer Research
Virtakoivu R, Mai A, Mattila E, De Franceschi N, Imanishi SY, Corthals G, Kaukonen R, Saari M, Cheng F, Torvaldson E, Kosma VM, Mannermaa A, Muharram G, Gilles C, Eriksson J, Soini Y, Lorens JB, Ivaska J
(A1 Refereed original research article in a scientific journal)
Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis (2014)
- Journal of Clinical Investigation
Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H, Ivaska J
(A1 Refereed original research article in a scientific journal)
Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells (2014)
- Developmental Cell
Muharram G, Sahgal P, Korpela T, De Franceschi N, Kaukonen R, Clark K, Tulasne D, Carpén O, Ivaska J
(A1 Refereed original research article in a scientific journal)
The Regulation and Role of c-FLIP in Human Th Cell Differentiation (2014)
- PLoS ONE
Kyläniemi Minna K, Kaukonen Riina, Myllyviita Johanna, Rasool Omid, Lahesmaa RIitta
(A1 Refereed original research article in a scientific journal)
Filopodia and adhesion in cancer cell motility (2011)
- Cell Adhesion and Migration
Arjonen Antti, kaukonen Riina, Ivaska Johanna
(A2 Refereed review article in a scientific journal )