Laura Kakkola
Adjunct Professor, Bioturvapäällikkö/Biosafety Officer
laura.kakkola@utu.fi +358 29 450 4555 +358 46 921 4211 Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0001-9271-4059 |
virology; immunology; infection; zoonoses; biosafety
I am a researcher with the cell biologist's background interested in intra-cellular events on infection, immunological responses (innate and adaptive), effect of host genetics in infectious diseases, and viruses' counteractions on these - including emerging pathogens, virus surveillance and diagnostics. I act as a Biosafety Officer at the Institute of Biomedicine and my responsibilities are to coordinate, supervise and educate laboratory work with infectious pathogens (viruses and bacteria). I am a Laboratory Manager in the Research Center Infections and Immunity, I teach on university courses, supervise MSc and PhD students, and conduct independent research.
My research interests are on virus-host interactions, how viruses interfere with immune responses, and could these events be utilized in vaccine, antiviral drug or diagnostic test development. At the moment I am working with coronaviruses, influenza viruses, filoviruses and flaviviruses.
I have taken the course on Medical pedagogics. I am co-supervising MSc and PhD students, and am a member of thesis committees for PhD students. I have given lectures and taught on laboratory courses at the university level.
- Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014. (2015) Mishel P, Ojala T, Benner C, Lakspere T, Bychkov D, Jalovaara P, Kakkola L, Kallio-Kokko H, Kantele A, Kankainen M, Ikonen N, Ripatti S, Julkunen I, Kainov DE.
(A1 Refereed original research article in a scientific journal) - Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland. (2015) Jalovaara P, Mishel P, Kallio-Kokko H, Valkonen M, Kantele A, Ikonen N, Julkunen I, Kakkola L, Kutsaya A, Vuorinen T, Mattila P, Almusa H, Kainov D.
(A1 Refereed original research article in a scientific journal) - Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland (2015) Jalovaara P, Mishel P, Kallio-Kokko H, Valkonen M, Kantele A, Ikonen N, Julkunen I, Kakkola L, Kutsaya A, Vuorinen T, Mattila P, Almusa H, Kainov D
(A1 Refereed original research article in a scientific journal) - Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013 (2014) Triin Lakspere, Janne Tynell, Minttu Kaloinen, Maarten Vanlede, Alun Parsons, Niina Ikonen, Hannimari Kallio-Kokko, Anu Kantele, Pirkko Mattila, Henrikki Almusa, Ilkka Julkunen, Denis Kainova, Laura Kakkola
(B1 Non-refereed article in a scientific journal) - Full-Genome Sequences of Influenza H3N2 Virus Strains Isolated from Finnish Patients during the 2012-2013 Epidemic Season (2014) Lakspere T, Kallio-Kokko H, Kantele A, Mattila P, Almusa H, Kainov D, Kakkola L
(A1 Refereed original research article in a scientific journal) - Molecular evolution and epidemiology of echovirus 6 in Finland (2013)
- Infection, Genetics and Evolution
(A1 Refereed original research article in a scientific journal) - Emerging cellular targets for influenza antiviral agents (2012)
- Trends in Pharmacological Sciences
(A2 Refereed review article in a scientific journal ) - Replication of and protein synthesis by TT viruses (2009)
- Current Topics in Microbiology and Immunology
(A2 Refereed review article in a scientific journal ) - Expression of all six human Torque teno virus (TTV) proteins in bacteria and in insect cells, and analysis of their IgG responses (2008)
- Virology
(A1 Refereed original research article in a scientific journal) - VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones (2008)
- Virology
(A1 Refereed original research article in a scientific journal) - Biological and immunological relations among human parvovirus B19 genotypes 1 to 3. (2007)
- Journal of Virology
(A1 Refereed original research article in a scientific journal) - Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6. (2007)
- FEBS Journal
(A1 Refereed original research article in a scientific journal) - Human circovirus TT virus genotype 6 expresses six proteins following transfection of a full-length clone (2005)
- Journal of Virology
(A1 Refereed original research article in a scientific journal) - Genoprevalence in human tissues of TT-virus genotype 6. (2004)
- Archives of Virology
(A1 Refereed original research article in a scientific journal) - Cloning and sequencing of TT virus genotype 6 and expression of antigenic open reading frame 2 proteins (2002)
- Journal of General Virology
(A1 Refereed original research article in a scientific journal) - Predictors of biological aggressiveness of prostate specific antigen screening detected prostate cancer (2001)
- Journal of Urology
(A1 Refereed original research article in a scientific journal) - Androgen receptor gene amplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer (2000)
- Journal of Urology
(A1 Refereed original research article in a scientific journal) - Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer (1999)
- American Journal of Pathology
(A1 Refereed original research article in a scientific journal) - Genetic alterations in hormone-refractory recurrent prostate carcinomas (1998)
- American Journal of Pathology
(A1 Refereed original research article in a scientific journal) - Intracellular route of canine parvovirus entry (1998)
- Journal of Virology
(A1 Refereed original research article in a scientific journal)