Tomas Keller - UTU Research Portal

Tomas Keller

- Senior Researcher,
Turku PET Centre (Independent units)

tomkel@utu.fi

Publications

Evaluation of PET imaging as a tool for detecting neonatal hypoxic-ischemic encephalopathy in a preclinical animal model (2024)
- Experimental Neurology
Saha Emma, Shimochi Saeka, Keller Thomas, Eskola Olli, López-Picón Francisco, Rajander Johan, Löyttyniemi Eliisa, Forsback Sarita, Solin Olof, Grönroos Tove, Parikka Vilhelmiina
(A1 Refereed original research article in a scientific journal)
Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA (2024)
- EJNMMI Research
Alzghool Obada M., Aarnio Richard, Helin Jatta S., Wahlroos Saara, Keller Thomas, Matilainen Markus, Solis Junel, Danon Jonathan J., Kassiou Michael, Snellman Anniina, Solin Olof, Rinne Juha O., Haaparanta-Solin Merja
(A1 Refereed original research article in a scientific journal)
Non-invasive quantification of stem cell-derived islet graft size and composition (2024)
- Diabetologia
Lithovius, Väinö; Lahdenpohja, Salla; Ibrahim, Hazem; Saarimäki-Vire, Jonna; Uusitalo, Lotta; Montaser, Hossam; Mikkola, Kirsi; Yim, Cheng-Bin; Keller, Thomas; Rajander, Johan; Balboa, Diego; Barsby, Tom; Solin, Olof; Nuutila, Pirjo; Grönroos, Tove J.; Otonkoski, Timo
(A1 Refereed original research article in a scientific journal)
Evaluation of [18F]FMTEB in Sprague Dawley rats as a PET tracer for metabotropic glutamate receptor 5 (2023)
- Nuclear Medicine and Biology
Krzyczmonik Anna, Grafinger Katharina E., Keller Thomas, Pfeifer Lukas, Forsback Sarita, Haaparanta-Solin Merja, Gouverneur Veronique, López-Picón Francisco, Solin Olof
(A1 Refereed original research article in a scientific journal)
Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls (2022)
- Molecular Imaging and Biology
López-Picón Francisco R, Keller Thomas, Bocancea Diana, Helin Jatta S, Krzyczmonik Anna, Helin Semi, Damont Annelaure, Dollé Frédéric, Rinne Juha O, Haaparanta-Solin Merja, Solin Olof
(A1 Refereed original research article in a scientific journal)
Evaluation of [F-18]F-DPA PET for Detecting Microglial Activation in the Spinal Cord of a Rat Model of Neuropathic Pain (2022)
- Molecular Imaging and Biology
Shimochi Saeka, Keller Thomas, Kujala Ella, Khabbal Joonas, Rajander Johan, Löyttyniemi Eliisa, Solin Olof, Nuutila Pirjo, Kanaya Shigehiko, Yatkin Emrah, Grönroos Tove J., Iida Hidehiro
(A1 Refereed original research article in a scientific journal)
Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist (2021)
- Theranostics
Zhang Lijian, Zhuang Xiaoqing, Kotitalo Päivi, Keller Thomas, Krzyczmonik Anna, Haaparanta-Solin Merja, Solin Olof, Forsback Sarita, Grönroos Tove J, Han Chunlei, López-Picón Francisco R, Xia Hechun
(A1 Refereed original research article in a scientific journal)
Automated GMP production and long-term experience in radiosynthesis of CB(1)tracer [F-18]FMPEP-d(2) (2020)
- Journal of Labelled Compounds and Radiopharmaceuticals
Salla Lahdenpohja, Thomas Keller, Sarita Forsback, Tapio Viljanen, Esa Kokkomäki, Riikka V. Kivelä, Jörgen Bergman,Olof Solin, Anna K. Kirjavainen
(A1 Refereed original research article in a scientific journal)
Comparison of high and low molar activity TSPO tracer [18F]F-DPA in a mouse model of Alzheimer’s disease (2020)
- Journal of Cerebral Blood Flow and Metabolism
Keller T., López-Picón F.R., Krzyczmonik A., Forsback S., Takkinen J.S., Rajander J., Teperi S., Dollé F., Rinne J.O., Haaparanta-Solin M., Solin O.
(A1 Refereed original research article in a scientific journal)
Radiosynthesis and Preclinical Evaluation of an α2A-Adrenoceptor Tracer Candidate, 6-[18F]Fluoro-marsanidine (2019)
- Molecular Imaging and Biology
Krzyczmonik A., Keller T., López-Picón F., Forsback S., Kirjavainen A.K., Takkinen J.S., Wasilewska A., Scheinin M., Haaparanta-Solin M., Solin O.
(A1 Refereed original research article in a scientific journal)
Radiosynthesis of [¹⁸F]F-DPA with various molar activities for the imaging of neuroinflammation (2019) Keller Thomas
(G5 Article dissertation )
Radiosynthesis of the norepinephrine transporter tracer [F-18]NS12137 via copper-mediated F-18-labelling (2019)
- Journal of Labelled Compounds and Radiopharmaceuticals
Salla Lahdenpohja, Thomas Keller, Johan Rajander, Anna K. Kirjavainen
(A1 Refereed original research article in a scientific journal)
[18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease (2018)
- Nuclear Medicine and Biology
Keller T, López-Picón FR, Krzyczmonik A, Forsback S, Kirjavainen AK, Takkinen JT, Alzghool O, Rajander J, Teperi S, Cacheux F, Damont A, Dollé F, Rinne JO, Solin O, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging (2017)
- Journal of Cerebral Blood Flow and Metabolism
Jatta S Takkinen, Francisco R López-Picón, Rana Al Majidi, Olli Eskola, Anna Krzyczmonik, Thomas Keller, Eliisa Löyttyniemi, Olof Solin, Juha O Rinne, Merja Haaparanta-Solin
(A1 Refereed original research article in a scientific journal)
Radiosynthesis and Preclinical Evaluation of [F-18]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats (2017)
- Molecular Imaging and Biology
Keller T, Krzyczmonik A, Forsback S, Picon FRL, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dolle F, Rinne JO, Haaparanta-Solin M, Solin O
(A1 Refereed original research article in a scientific journal)
Use of SF6 for the production of electrophilic 18F-fluorination reagents (2017)
- Journal of Fluorine Chemistry
Anna Krzyczmonik, Thomas Keller, Anna K. Kirjavainen, Salla Lahdenpohja, Sarita Forsback, Olof Solin
(A1 Refereed original research article in a scientific journal)
Vacuum ultraviolet photon-mediated production of [F-18]F-2 (2017)
- Journal of Labelled Compounds and Radiopharmaceuticals
Krzyczmonik A, Keller T, Kirjavainen AK, Forsback S, Solin O
(A1 Refereed original research article in a scientific journal)
HPLC and TLC methods for analysis of [F-18]flumazenil and its metabolites from biological samples (2016)
- European Journal of Nuclear Medicine and Molecular Imaging
Grafinger K, Keller T, Krzyczmonik A, Pfeifer L, Lopez-Picon FR, Forsback S, Solin O, Gouverneur V, Haaparanta-Solin M
(Other publication)
Organomediated Enantioselective 18F-Fluorination for PET Applications (2015)
- Angewandte Chemie International Edition
Buckingham F, Kirjavainen AK, Forsback S, Krzyczmonik A, Keller T, Newington IM, Glaser M, Luthra SK, Solin O, Gouverneur V,
(A1 Refereed original research article in a scientific journal)
PET imaging and ex vivo brain autoradiography in a mouse model of Alzheimers disease using the TSPO tracers [F-18]DPA-714 and [F-18]F-DPA (2015)
- Journal of Labelled Compounds and Radiopharmaceuticals
Haaparanta-Solin Merja, López-Picón Francisco, Almajidi Rana, Takkinen Jatta, Keller Thomas, Krzyczmonik Anna, Forsback Sarita, Kirjavainen Anna, Cacheux Fanny, Damont Annelaure, Rinne Juha O, Dollé Frédéric, Solin Olof
(Other publication)