Laura Ekblad
MD, PhD
Areas of expertise
positron emission tomography; Alzheimer´s Disease; Insulin resistance; cognition; memory disorders
Research community or research topic
Specialist in Geriatrics and Family Medicine. Senior researcher, Turku Alzheimer Imaging Group, Turku PET Centre.
Research
My research focuses on early risk factors for memory disorders, especially Alzheimer´s disease. I am particularly interested in the associations between metabolic risk factors (insulin resistance, glucose intolerance, obesity) and cognitive decline.
Our lab uses multimodal neuroimaging (PET-imaging, MRI) combined with blood and CSF biomarkers and cognitive testing to explore the association between different risk factors and early cerebral changes of memory disorders.
I also run a project that examines possible cardiac side effects of anti-dementia agents in elderly memory clinic patients.
Publications
- Valmistautuminen muistisairauksiin vanhusväestössä - askelmat ja osapuoletBlood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly (2026)
- DuodecimAlzheimer's Research and Therapy
Roitto, Hanna-Maria; Ekblad, Laura
(A2 Refereed review article in a scientific journal )
- APOE4 carriership status influences [11C]PiB white matter retention in cognitively healthy older adults (2025)
- Neurobiology of DiseaseNeurobiology of Disease
Tato-Fernández Claudia; Ekblad Laura L.; Bucci Marco; Tuisku Jouni; Parkkola Riitta; Helin Semi; Rinne Juha O.; Snellman Anniina
(A1 Refereed original research article in a scientific journal)
- Associations of lifestyle factors with amyloid pathology in persons without dementia (2025)
- Journal of Alzheimer's Disease
Oomens, Julie E.; Vos, Stephanie J. B.; Maserejian, Nancy N.; Boada, Mercè; Didic, Mira; Engelborghs, Sebastiaan; Fladby, Tormod; van der Flier, Wiesje M.; Frisoni, Giovanni B.; Fröhlich, Lutz; Gill, Kiran Dip; Grimmer, Timo; Hort, Jakub; Itoh, Yoshiaki; Iwatsubo, Takeshi; Klimkowicz-Mrowiec, Aleksandra; Landau, Susan M.; Lee, Dong Young; Lleó, Alberto; Martinez-Lage, Pablo; de Mendonça, Alexandre; Meyer, Philipp T.; Parchi, Piero; Pardini, Matteo; Parnetti, Lucilla; Popp, Julius; Rami, Lorena; Reiman, Eric M.; Rinne, Juha O.; Rodrigue, Karen M.; Sánchez-Juan, Pascual; Santana, Isabel; Scarmeas, Nikolaos; Scheltens, Philip; Skoog, Ingmar; Sperling, Reisa A.; Stern, Yaakov; Villeneuve, Sylvia; Waldemar, Gunhild; Wiltfang, Jens; Zetterberg, Henrik; Alcolea, Daniel; Allegri, Ricardo F.; Altomare, Daniele; Bateman, Randall J.; Baiardi, Simone; Baldeiras, Ines; Blennow, Kaj; den Braber, Anouk; van Buchem, Mark A.; Byun, Min Soo; Cerman, Jiří; Chen, Kewei; Chipi, Elena; Day, Gregory S.; Drzezga, Alexander; Ekblad, Laura L.; Förster, Stefan; Fortea, Juan; Freund-Levi, Yvonne; Frings, Lars; Guedj, Eric; Habeck, Christian G.; Handels, Ron; Hausner, Lucrezia; Hellwig, Sabine; Jiménez-Bonilla, Julio F.; Juaristi, Ane Iriondo; Kandimalla, Ramesh; Kern, Silke; Bordewick Kirsebom, Bjørn-Eivind S.; Kornhuber, Johannes; Legdeur, Nienke; Levin, Johannes; Maier, Wolfgang; Marquié, Marta; Minatani, Shinobu; Morbelli, Silvia Daniela; Mroczko, Barbara; Ntanasi, Eva; de Oliveira, Catarina Resende; Orellana, Adelina; Peters, Oliver; Prabhakar, Sudesh; Ramakers, Inez H.; Rodríguez-Rodriguez, Eloy; Ruiz, Agustín; Rüther, Eckart; Sakhardande, Jayant; Selnes, Per; Silva, Dina; Soininen, Hilkka; Spiru, Luiza; Takeda, Akitoshi; Teunissen, Charlotte E.; Tijms, Betty M.; Vermunt, Lisa; Wallin, Åsa K.; Wiels, Wietse; Yannakoulia, Mary; Yi, Dahyun; Zettergren, Anna; Alzheimer's Disease Neuroimaging Initiative (ADNI); A4 Study group; Dominantly Inherited Alzheimer Network (DIAN); European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI); Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE); Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research group; Ossenkoppele, Rik; Verhey, Frans R. J.; Visser, Pieter Jelle; Jansen, Willemijn J.
(A1 Refereed original research article in a scientific journal)
- Depressive Symptoms and Amyloid Pathology (2025) Wiels, Wietse A.; Oomens, Julie E.; Engelborghs, Sebastiaan; Baeken, Chris; von Arnim, Christine A.F.; Boada, Mercè; Didic, Mira; Dubois, Bruno; Fladby, Tormod; van der Flier, Wiesje M.; Frisoni, Giovanni B.; Fröhlich, Lutz; Gill, Kiran Dip; Grimmer, Timo; Hildebrandt, Helmut; Hort, Jakub; Itoh, Yoshiaki; Iwatsubo, Takeshi; Klimkowicz-Mrowiec, Aleksandra; Lee, Dong Young; Lleó, Alberto; Martinez-Lage, Pablo; de Mendonça, Alexandre; Meyer, Philipp T.; Kapaki, Elisabeth N.; Parchi, Piero; Pardini, Matteo; Parnetti, Lucilla; Popp, Julius; Rami, Lorena; Reiman, Eric M.; Rinne, Juha O.; Rodrigue, Karen M.; Sánchez-Juan, Pascual; Santana, Isabel; Sarazin, Marie; Scarmeas, Nikolaos; Skoog, Ingmar; Snyder, Peter J.; Sperling, Reisa A.; Villeneuve, Sylvia; Wallin, Anders; Wiltfang, Jens; Zetterberg, Henrik; Ossenkoppele, Rik; Verhey, Frans R. J.; Vos, Stephanie J. B.; Visser, Pieter Jelle; Jansen, Willemijn J.; Alcolea, Daniel; Altomare, Daniele; Baiardi, Simone; Baldeiras, Ines; Bateman, Randall J.; Blennow, Kaj; Bottlaender, Michel; den Braber, Anouk; van Buchem, Mark A.; Byun, Min Soo; Cerman, Jiří; Chen, Kewei; Chipi, Elena; Day, Gregory S.; Drzezga, Alexander; Eckerström, Marie; Ekblad, Laura L.; Epelbaum, Stéphane; Förster, Stefan; Fortea, Juan; Freund-Levi, Yvonne; Frings, Lars; Guedj, Eric; Hausner, Lucrezia; Hellwig, Sabine; Huey, Edward D.; Jiménez-Bonilla, Julio F.; Johnson, Keith A.; Juaristi, Ane Iriondo; Kandimalla, Ramesh; Paraskevas, George; Kern, Silke; Kirsebom, Bjørn-Eivind S.; Kornhuber, Johannes; Lagarde, Julien; Landau, Susan M.; Legdeur, Nienke; Llibre Guerra, Jorge J.; Maserejian, Nancy N.; Marquié, Marta; Minatani, Shinobu; Morbelli, Silvia Daniela; Mroczko, Barbara; Ntanasi, Eva; de Oliveira, Catarina Resende; Olivieri, Pauline; Orellana, Adelina; Perrin, Richard J.; Peters, Oliver; Prabhakar, Sudesh; Ramakers, Inez H.; Rodríguez-Rodriguez, Eloy; Ruiz, Agustín; Rüther, Eckart; Selnes, Per; Silva, Dina; Soininen, Hilkka; Spiru, Luiza; Takeda, Akitoshi; Teichmann, Marc; Tijms, Betty M.; Teunissen, Charlotte E.; Thompson, Loisa I.; Vogelgsangs, Jonathan; Vöglein, Jonathan; Waldemar, Gunhild; Wallin, Åsa K.; Yannakoulia, Mary; Yi, Dahyun; Zettergren, Anna.
(A1 Refereed original research article in a scientific journal)
- Effects of Cholinesterase Inhibitor Medication on QTc Interval in Memory Clinic Patients (2025)
- Annals of Pharmacotherapy
Isotalo, Hanna Karita; Lehtovaara, Joanna Karoliina; Ekblad, Laura Linnea; Nuotio, Maria Susanna; Langén, Ville Lauri Johannes
(A1 Refereed original research article in a scientific journal)
- Enhancing dementia prediction: A 19-year validation of the CAIDE risk score with insulin resistance and APOE ε4 integration in a population-based cohort (2025)
- The Journal of Prevention of Alzheimer's Disease
Pietilä, Elina; Löyttyniemi, Eliisa; Koskinen, Seppo; Lehtisalo, Jenni; Viitanen, Matti; Rinne, Juha O; Jula, Antti; Ekblad, Laura L
(A1 Refereed original research article in a scientific journal)
- Metabolic dysfunction-associated steatotic liver disease as a predictor of cognitive performance: An 11-year population-based follow-up study (2025)
- Digestive and Liver Disease
Vataja, Emilia; Viitanen, Matti; Rinne, Juha O; Lehtisalo, Jenni; Erlund, Iris; Ngandu, Tiia; Koskinen, Seppo; Åberg, Fredrik; Jula, Antti; Ekblad, Laura
(A1 Refereed original research article in a scientific journal)
- Neuroinflammation in Parkinson’s disease : A study with [11C]PBR28 PET and cerebrospinal fluid markers (2025)
- Parkinsonism and Related Disorders
Al-Abdulrasul, H.; Ajalin, R.; Tuisku, J.; Zetterberg, H.; Blennow, K.; Vahlberg, T.; Ekblad, L.; Helin, S.; Forsback, S.; Rinne, J.O.; Brück, A.
(A1 Refereed original research article in a scientific journal)
- (2024) Koivumäki, Mikko; Ekblad, Laura; Lantero-Rodriguez, Juan; Ashton, Nicholas J.; Karikari, Thomas K.; Helin, Semi; Parkkola, Riitta; Lötjönen, Jyrki; Zetterberg, Henrik; Blennow, Kaj; Rinne, Juha O.; Snellman, Anniina
(A1 Refereed original research article in a scientific journal)
- Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET (2024) Tato-Fernández, Claudia; Ekblad, Laura L.; Pietilä, Elina; Saunavaara, Virva; Helin, Semi; Parkkola, Riitta; Zetterberg, Henrik; Blennow, Kaj; Rinne, Juha O.; Snellman, Anniina
(A1 Refereed original research article in a scientific journal)
