Timo Laitio
MD, PhD
Intensive care medicine; pharmacological neuroprotection; cardioprotection; risk stratification
- Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial (2025)
- Neurocritical CareResuscitation
Hollmén, Carita; Parkkola, Riitta; Vorobyev, Viktor; Saunavaara, Jani; Laitio, Ruut; Arola, Olli; Hynninen, Marja; Bäcklund, Minna; Martola, Juha; Ylikoski, Emmi; Roine, Risto O.; Tiainen, Marjaana; Scheinin, Harry; Maze, Mervyn; Vahlberg, Tero; Laitio, Timo T.
- A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest : A post-hoc study of the randomised Xe-Hypotheca trialSevere or critical hypotension during post cardiac arrest care is associated with factors available on admission - a post hoc analysis of the TTH48 trial (2024)
- PLoS ONEJournal of Critical Care
Nummela, Aleksi J.; Scheinin, Harry; Perola, Markus; Joensuu, Anni; Laitio, Ruut; Arola, Olli; Grönlund, Juha; Roine, Risto O.; Bäcklund, Minna; Vahlberg, Tero J.; Laitio, Timo; Xe-Hypotheca Collaboration Group
- Potassium disorders at intensive care unit admission and functional outcomes after cardiac arrest (2024) Holm, Aki; Lascarrou; Alain Cariou,Jean Baptiste; Reinikainen, Matti; Laitio, Timo; Kirkegaard, Hans; Søreide, Eldar; Taccone, Fabio Silvio; Lääperi, Mitja; Skrifvars, Markus B.
- Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trial (2023) Koskensalo Kalle, Virtanen Sami, Saunavaara Jani, Parkkola Riitta, Laitio Ruut, Arola Olli, Hynninen Marja, Silvasti Päivi, Nukarinen Eija, Martola Juha, Silvennoinen Heli M, Tiainen Marjaana, Roine Risto O, Scheinin Harry, Saraste Antti, Maze Mervyn, Vahlberg Tero, Laitio Timo T; XeHYPOTHECA Research Group
- Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine (2023) Kantonen Oskari, Laaksonen Lauri, Alkire Michael, Scheinin Annalotta, Långsjö Jaakko, Kallionpää Roosa E., Kaisti Kaike, Radek Linda, Johansson Jarkko, Laitio Timo, Maksimow Anu, Scheinin Joonas, Nyman Mikko, Scheinin Mika, Solin Olof, Vahlberg Tero, Revonsuo Antti, Valli Katja, Scheinin Harry
- Dysnatremia at ICU admission and functional outcome of cardiac arrest: insights from four randomised controlled trialsThe influence of prolonged temperature management on acute kidney injury after out-of-hospital cardiac arrest: A post hoc analysis of the TTH48 trial (2023)
- Critical CareResuscitation
Lascarrou Jean Baptiste, Ermel Cyrielle, Cariou Alain, Laitio Timo, Kirkegaard Hans, Søreide Eldar, Grejs Anders M., Reinikainen Matti, Colin Gwenhael, Taccone Fabio Silvio, Le Gouge Amélie, Skrifvars Markus B.
- Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial (2023) Laaksonen Mikael, Rinne Jaakko, Rahi Melissa, Posti Jussi P., Laitio Ruut, Kivelev Juri, Saarenpää Ilkka, Laukka Dan, Frösen Juhana, Ronkainen Antti, Bendel Stepani, Långsjö Jaakko, Ala-Peijari Marika, Saunavaara Jani, Parkkola Riitta, Nyman Mikko, Martikainen Ilkka K., Dickens Alex M., Rinne Juha, Valtonen Mika, Saari Teijo I., Koivisto Timo, Bendel Paula, Roine Timo, Saraste Antti, Vahlberg Tero, Tanttari Juha, Laitio Timo
- Effects of dexmedetomidine, propofol, sevoflurane and S-ketamine on the human metabolome: A randomised trial using nuclear magnetic resonance spectroscopy (2022)
- European Journal of Anaesthesiology
Nummela Aleksi J, Laaksonen Lauri T, Laitio Timo T, Kallionpää RoosaE, Långsjö Jaakko W, Scheinin Joonas M, Vahlberg Tero J, Koskela Harri T, Aittomäki Viljami, Valli Katja J, Revonsuo Antti, Niemi Mikko, Perola Markus, Scheinin Harry
- Electrolyte profiles with induced hypothermia: A sub study of a clinical trial evaluating the duration of hypothermia after cardiac arrest (2022)
- Acta Anaesthesiologica Scandinavica
Kirkegaard Hans, Grejs Anders M., Gudbjerg Simon, Duez Christophe, Jeppesen Anni, Hassager Christian, Laitio Timo, Storm Christian, Taccone Fabio Silvio, Skrifvars Markus B., Søreide Eldar
- Effect of Inhaled Xenon on Cardiac Function in Comatose Survivors of Out-of-Hospital Cardiac Arrest—A Substudy of the Xenon in Combination With Hypothermia After Cardiac Arrest Trial (2021)
- Critical Care Explorations
Saraste Antti, Ballo Haitham, Arola Olli, Laitio Ruut, Airaksinen Juhani, Hynninen Marja, Bäcklund Minna, Ylikoski Emmi, Wennervirta Johanna, Pietil Mikko, Roine Risto O., Harjola Veli-Pekka, Niiranen Jussi, Korpi Kirsi, Varpula Marjut, Scheinin Harry, Maze Mervyn, Vahlberg Tero, Laitio Timo
- Factors Associated With Rebound Hyperthermia After Targeted Temperature Management in Out-of-Hospital Cardiac Arrest Patients: An Explorative Substudy of the Time-Differentiated Therapeutic Hypothermia in Out-of-Hospital Cardiac Arrest Survivors Trial (2021)
- Critical Care Explorations
Holm Aki, Kirkegaard Hans, Taccone Fabio Silvio, Søreide Eldar, Grejs Anders M., Toome Valdo, Hassager Christian, Rasmussen Bodil S., Laitio Timo, Storm Christian, Hästbacka Johanna, Skrifvars Markus B.
- On no man’s land: Subjective experiences during unresponsive and responsive sedative states induced by four different anesthetic agents (2021)
- Consciousness and Cognition
Radek Linda, Koskinen Lauri, Sandman Nils, Laaksonen Lauri, Kallionpää Roosa E., Scheinin Annalotta, Rajala Ville, Maksimow Anu, Laitio Timo, Revonsuo Antti, Scheinin Harry, Valli Katja
- Quality of targeted temperature management and outcome of out-of-hospital cardiac arrest patients: A post hoc analysis of the TTH48 study2021 De Fazio Chiara, Skrifvars Markus B, Søreide Eldar, Grejs Anders M., Di Bernardini Eugenio, Jeppesen Anni N., Storm Christian, Kjaergaard Jesper, Laitio Timo, Rasmussen Bodil S., Tianen Marjaana, Kirkegaard Hans, Taccone Fabio S.; on behalf of TTH48 Investigators
- 2021 Hästbacka Johanna, Kirkegaard Hans, Soreide Eldar, Taccone Fabio Silvio, Rasmussen Bodil Steen, Storm Christian, Kjaergaard Jesper, Laitio Timo, Duez Christophe Henri Valdemar, Jeppesen Anni N, Grejs Anders M, Skrifvars Markus B
- Cold fluids for induction of targeted temperature management: A sub-study of the TTH48 trial (2020) Holm A, Kirkegaard H, Taccone F, Soreide E, Grejs A, Duez C, Jeppesen A, Toome V, Hassager CC, Rasmussen BS, Laitio T, Storm C, Hastbacka J, Skrifvars MB
- Haemodynamics and vasopressor support during prolonged targeted temperature management for 48 hours after out-of-hospital cardiac arrest: a post hoc substudy of a randomised clinical trial (2020)
- European Heart Journal: Acute Cardiovascular Care
Johannes Grand, Christian Hassager, Markus B Skrifvars, Marjaana Tiainen, Anders M Grejs, Anni Nørgaard Jeppesen, Christophe Henri Valdemar Duez, Bodil S Rasmussen, Timo Laitio, Jens Nee, FabioSilvio Taccone, Eldar Søreide, Hans Kirkegaard
- (2020) Kristian Strand, Eldar Søreide, Hans Kirkegaard, Fabio Silvio Taccone, Anders Morten Grejs, Christophe Henri Valdemar Duez, Anni Nørgaard Jeppesen, Christian Storm, Bodil Steen Rasmussen, Timo Laitio, Christian Hassager, Valdo Toome, Johanna Hästbacka, Markus B. Skrifvars
- Hypothermic to ischemic ratio and mortality in post-cardiac arrest patients (2019)
- Acta Anaesthesiologica Scandinavica
Markus B. Skrifvars, Eldar Soreide, Kelly N. Sawyer, Fabio S. Taccone, Valdo Toome, Christian Storm, Anni Jeppesen, Anders Grejs, Christophe H. V. Duez, Marjaana Tiainen, Bodil S. Rasmussen, Timo Laitio, Christian Hassager, Hans Kirkegaard
- Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial (2019) De Fazio C, Skrifvars MB, Soreide E, Creteur J, Grejs AM, Kjaergaard J, Laitio T, Nee J, Kirkegaard H, Taccone FS
- Ksenonin aivoja ja sydäntä suojaavat vaikutukset (2019) Laitio R, Laitio T
