Olli Tenovuo
MD, PhD, Prof. of Neurotraumatology
Asiantuntijuusalueet
traumatic brain injury; rehabilitation; biomarkers; imaging
Tutkimusyhteisö tai tutkimusaihe
Tapaturmaisten aivovammojen patofysiologia, diagnostiikka, hoito ja ennuste
Biografia
I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.
Tutkimus
The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.
Opetus
Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.
Julkaisut
- Peripheral nervous system involvement in primary burning mouth syndromeresults of a pilot study (2016) Puhakka A, Forssell H, Soinila S, Virtanen A, Roytta M, Laine M, Tenovuo O, Teerijoki-Oksa T, Jaaskelainen SK
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Pohjoismainen hoitosuositus avuksi pään vammojen arviointiin (2016) Luoto T, Tenovuo O
(D1 Artikkeli ammattilehdessä)
- Prediction of Outcome after Traumatic Brain Injury: Comparison of Disease State Index and IMPACT Calculator (2016)
- Studies in Health Technology and Informatics
Liedes H, Mattila J, Lingsma H, Lötjönen J, Menon D, Tenovuo O, van Gils M
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Reproducibility of Tract-based and Region-of-Interest DTI Analysis of Long Association Tracts (2016) Brandstack N., Kurki T., Laalo J., Kauko T., Tenovuo O.
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Scandinavian guidelines for initial management of minor and moderate head trauma in children (2016) Astrand R, Rosenlund C, Undén J; and for the Scandinavian Neurotrauma Committee (SNC)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- The Cholinergic Potential, the Vagus Nerve and Challenges in Treatment of Traumatic Brain Injury (2016)
- Current Pharmaceutical Design
Uteshev VV, Tenovuo O, Gaidhani N
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury: Correlations With Clinical and Imaging Findings (2016) Posti JP, Takala RSK, Runtti H, Newcombe VF, Outtrim J, Katila AJ, Frantzen J, Ala-Seppala H, Coles JP, Hossain MI, Kyllonen A, Maanpaa HR, Tallus J, Hutchinson PJ, van Gils M, Menon DK, Tenovuo O
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Variation in structure and process of care in traumatic brain injury: Provider profiles of European Neurotrauma Centers participating in the CENTER-TBI study (2016) Cnossen M., Polinder S., Lingsma H., Maas A., Menon D., Steyerberg E., Adams H., Alessandro M., Allanson J., Amrein K., Andaluz N., Andelic N., Andrea N., Andreassen L., Anke A., Antoni A., Ardon H., Audibert G., Auslands K., Azouvi P., Baciu C., Bacon A., Badenes R., Baglin T., Bartels R., Barzó P., Bauerfeind U., Beer R., Belda F., Bellander B., Belli A., Bellier R., Benali H., Benard T., Berardino M., Beretta L., Beynon C., Bilotta F., Binder H., Biqiri E., Blaabjerg M., Borgen L., Bouzat P., Bragge P., Brazinova A., Brehar F., Brorsson C., Buki A., Bullinger M., Bučková V., Calappi E., Cameron P., Carbayo L., Carise E., Carpenter C., Castaño-León A., Causin F., Chevallard G., Chieregato A., Citerio G., Coburn M., Coles J., Cooper J., Correia M., Covic A., Curry N., Czeiter E., Czosnyka M., Dahyot-Fizelier C., Damas F., Damas P., Dawes H., De Keyser V., Della Corte F., Depreitere B., Ding S., Dippel D., Dizdarevic K., Dulière G., Dzeko A., Eapen G., Engemann H., Ercole A., Esser P., Ezer E., Fabricius M., Feigin V., Feng J., Foks K., Fossi F., Francony G., Frantzén J., Freo U., Frisvold S., Furmanov A., Gagliardo P., Galanaud D., Gao G., Geleijns K., Ghuysen A., Giraud B., Glocker B., Gomez P., Grossi F., Gruen R., Gupta D., Haagsma J., Hadzic E., Haitsma I., Hartings J., Helbok R., Helseth E., Hertle D., Hill S., Hoedemaekers A., Hoefer S., Hutchinson P., Håberg A., Jacobs B., Janciak I., Janssens K., Jiang J., Jones K., Kalala J., Kamnitsas K., Karan M., Karau J., Katila A., Kaukonen M., Keeling D., Kerforne T., Ketharanathan N., Kettunen J., Kivisaari R., Kolias A., Kolumbán B., Kompanje E., Kondziella D., Koskinen L., Kovács N., Kálovits F., Lagares A., Lanyon L., Laureys S., Lauritzen M., Lecky F., Ledig C., Lefering R., Legrand V., Lei J., Levi L., Lightfoot R., Lingsma H., Loeckx D., Lozano A., Luddington R., Luijten-Arts C., Maas A., MacDonald S., MacFayden C., Maegele M., Majdan M., Major S., Manara A., Manhes P., Manley G., Martin D., Martino C., Maruenda A., Maréchal H., Mastelova D., Mattern J., McMahon C., Melegh B., Menovsky T., Morganti-Kossmann C., Mulazzi D., Mutschler M., Mühlan H., Negru A., Nelson D., Neugebauer E., Newcombe V., Noirhomme Q., Nyirádi J., Oddo M., Oldenbeuving A., Oresic M., Ortolano F., Palotie A., Parizel P., Patruno A., Payen J., Perera N., Perlbarg V., Persona P., Peul W., Pichon N., Piilgaard H., Piippo A., Pili F., Pirinen M., Ples H., Pomposo I., Psota M., Pullens P., Puybasset L., Ragauskas A., Raj R., Rambadagalla M., Rehorčíková V., Rhodes J., Richardson S., Ripatti S., Rocka S., Rodier N., Roe C., Roise O., Roks G., Romegoux P., Rosand J., Rosenfeld J., Rosenlund C., Rosenthal G., Rossaint R., Rossi S., Rostalski T., Rueckert D., Ruiz De Arcaute F., Rusnák M., Sacchi M., Sahakian B., Sahuquillo J., Sakowitz O., Sala F., Sanchez-Pena P., Sanchez-Porras R., Sandor J., Santos E., Sasse N., Sasu L., Savo D., Schipper I., Schlößer B., Schmidt S., Schneider A., Schoechl H., Schoonman G., Schou R., Schwendenwein E., Schöll M., Sir Ö., Skandsen T., Smakman L., Smeets D., Smielewski P., Sorinola A., Stamatakis E., Stanworth S., Stegemann K., Steinbüchel N., Stevens R., Stewart W., Stocchetti N., Sundström N., Synnot A., Szabó J., Söderberg J., Taccone F., Tamás V., Tanskanen P., Tascu A., Taylor M., Te Ao B., Tenovuo O., Teodorani G., Theadom A., Thomas M., Tibboel D., Tolias C., Tshibanda J., Tudora C., Vajkoczy P., Valeinis E., Van Hecke W., Van Praag D., Van Roost D., Van Vlierberghe E., Vande Vyvere T., Vanhaudenhuyse A., Vargiolu A., Vega E., Verheyden J., Vespa P., Vik A., Vilcinis R., Vizzino G., Vleggeert-Lankamp C., Volovici V., Vulekovic P., Vámos Z., Wade D., Wang K., Wang L., Wildschut E., Williams G., Willumsen L., Wilson A., Wilson L., Winkler M., Ylén P., Younsi A., Zaaroor M., Zhang Z., Zheng Z., Zumbo F., De Lange S., De Ruiter G., Den Boogert H., Van Dijck J., Van Essen T., Van Heugten C., Van Der Jagt M., Van Der Naalt J., Polinder S., Cnossen M., Van Der Naalt J., Zumbo F., De Lange S., De Ruiter G., Den Boogert H., Van Dijck J., Van Essen T., Van Heugten C., Van Der Jagt M., Wilson L., Wilson A., Ylén P., Winkler M., Zaaroor M., Younsi A., Zheng Z., Zhang Z., Willumsen L.
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Clinical correlates of retrograde amnesia in mild traumatic brain injury (2015) Luoto TM, Iverson GL, Losoi H, Waljas M, Tenovuo O, Kataja A, Brander A, Ohman J
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): A Prospective Longitudinal Observational Study. (2015) Maas AI, Menon DK, Steyerberg EW, Citerio G, Lecky F, Manley GT, Hill S, Legrand V, Sorgner A; on behalf of the CENTER-TBI Participants and Investigators
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
