Suvi Ruohonen - UTU Research Portal

Suvi Ruohonen

- Docent,
Institute of Biomedicine (Faculty of Medicine)

suvi.ruohonen@utu.fi

Publications

1 of 2

Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosisHydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult micePeripherally Administered Y-2-Receptor Antagonist BIIE0246 Prevents Diet-Induced Obesity in Mice With Excess Neuropeptide Y, but Enhances Obesity in Control Mice (2024)
- FASEB Journal
Heikelä, Hanna; Mairinoja, Laura; Ruohonen, Suvi T.; Rytkönen, Kalle T.; de Brot, Simone; Laiho, Asta; Koskinen, Satu; Suomi, Tomi; Elo, Laura L.; Strauss, Leena; Poutanen, Matti
(A1 Refereed original research article in a scientific journal)
Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin pulsatility (2023)
- Metabolism
Velasco Immaculada, Franssen Delphine, Daza-Dueñas Silvia, Skrapits Katalin, Takács Szabolcs, Torres Encarnacion, Rodríguez-Vazquez Elvira, Ruiz-Cruz Miguel, León Silvia, Kukoricza Krisztina, Zhang Fu-Ping, Ruohonen Suvi, Luque-Cordoba Diego, Priego-Capote Feliciano, Gaytan Francisco, Ruiz-Pino Francisco, Hrabovszky Erik, Poutanen Matti, Vázquez Maria J, Tena-Sempere Manuel
(A1 Refereed original research article in a scientific journal)
Selective loss of kisspeptin signaling in oocytes causes progressive premature ovulatory failure (2022)
- Human ReproductionCurrent Diabetes Reports
Ruohonen Suvi T, Gaytan Francisco, Gaudi Andrea Usseglio, Velasco Inmaculada, Kukoricza Krisztina, Perdices-Lopez Cecilia, Franssen Delphine, Guler Ipek, Mehmood Arfa, Elo Laura L, Ohlsson Claes, Poutanen Matti, Tena-Sempere Manuel
(A1 Refereed original research article in a scientific journal)
(2020)
- American Journal of Physiology : Endocrinology and MetabolismJAMA: Journal of the American Medical Association
Heikelä Hanna, Ruohonen Suvi T, Adam Marion, Viitanen Riikka, Liljenbäck Heidi, Eskola Olli, Gabriel Michael, Mairinoja Laura, Pessia Alberto, Velagapudi Vidya, Roivainen Anne, Zhang Fu-Ping, Strauss Leena, Poutanen Matti
(A1 Refereed original research article in a scientific journal)
Role of kisspeptins in the control of the hypothalamic-pituitary-ovarian axis: old dogmas and new challengesEarly probiotic supplementation and the risk of celiac disease in children at genetic risk (2020)
- Fertility and SterilityNutrients
Suvi T. Ruohonen, Matti Poutanen, Manuel Tena-Sempere
(A2 Refereed review article in a scientific journal )
Association of gluten intake during the first 5 years of life with incidence of celiac disease autoimmunity and celiac disease among children at increased risk (2019)
Carin Andrén Aronsson, Hye-Seung Lee, Elin M. Hård af Segerstad, Ulla Uusitalo, Jimin Yang, Sibylle Koletzko, Edwin Liu, Kalle Kurppa, Polly J. Bingley, Jorma Toppari, Anette G. Ziegler, Jin-Xiong She, William A. Hagopian, Marian Rewers, Beena Akolkar, Jeffrey P. Krischer, Suvi M. Virtanen, Jill M. Norris, Daniel Agardh; for the TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
(2019)
Ulla Uusitalo , Carin Andren Aronsson , Xiang Liu, Kalle Kurppa, Jimin Yang, Edwin Liu, Jennifer Skidmore, Christiane Winkler, Marian J. Rewers, William A. Hagopian, Jin-Xiong She, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jill M. Norris, Suvi M. Virtanen, Jeffrey P. Krischer, Daniel Agardh; on behalf of the TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis (2019)
- Metabolism
Inmaculada Velasco, Silvia León, Alexia Barroso, Francisco Ruiz-Pino, Violeta Heras, Encarnación Torres, María León, Suvi T. Ruohonen, David García-Galiano, Antonio Romero-Ruiz, MiguelA.Sánchez-Garrido, Claes Olhsson, Juan M. Castellano, Juan Roa, Matti Poutanen, LeonorPinilla, María J. Vázquez, Manuel Tena-Sempere
(A1 Refereed original research article in a scientific journal)
Maternal Dietary Supplement Use and Development of Islet Autoimmunity in the offspring: the TEDDY Study (2019)
- Pediatric Diabetes
Silvis K, Aronsson CA, Liu X, Uusitalo U, Yang J, Tamura R, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler A, Akolkar B, Krischer J, Norris JM, Virtanen SM, Norris JM; the TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
Metabolite-related dietary patterns and the development of islet autoimmunity (2019)
- Scientific Reports
Randi K. Johnson, Lauren Vanderlinden, Brian C . DeFelice, Katerina Kechris, Ulla Uusitalo, Oliver Fiehn, Marci Sontag, Tessa Crume, Andreas Beyerlein, Åke Lernmark, Jorma Toppari, Anette-G. Ziegler, Jin-Xiong She, William Hagopian, Marian Rewers, Beena Akolkar, Jeffrey Krischer, Suvi M. Virtanen, Jill M. Norris; & The TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report (2019)
- Diabetes Care
Jeffrey P. Krischer, Xiang Liu, Kendra Vehik, Beena Akolkar, William A. Hagopian, Marian J. Rewers, Jin-Xiong She, Jorma Toppari, Anette-G. Ziegler, Åke Lernmark; and the TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children (2019)
- Diabetes
Endesfelder D, Castell WZ, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P, Achenbach P; for the TEDDY Study Group
(A1 Refereed original research article in a scientific journal)
Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress (2019)
- Scientific Reports
Nicole C . A. van Engeland, Freddy Suarez Rodriguez, Adolfo Rivero-Müller, Tommaso Ristori, Camille L. Duran, Oscar M. J. A. Stassen, Daniel Antfolk, Rob C. H. Driessen, Saku Ruohonen, Suvi T. Ruohonen, Salla Nuutinen,
Eriika Savontaus, Sandra Loerakker, Kayla J. Bayless, Marika Sjöqvist, Carlijn V. C . Bouten, John E. Eriksson, Cecilia M. Sahlgren
(A1 Refereed original research article in a scientific journal)
Hydroxysteroid (17 beta) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice (2018)
- FASEB Journal
Adam M, Heikelä H, Sobolewski C, Portius D, Mäki-Jouppila J, Mehmood A, Adhikari P, Esposito I, Elo LL, Zhang FP, Ruohonen ST, Strauss L, Foti M, Poutanen M
(A1 Refereed original research article in a scientific journal)
Increased Energy Expenditure, Lipolysis and Hyperinsulinemia Confer Resistance to Central Obesity and Type 2 Diabetes in Mice Lacking Alpha2α-Adrenoceptors (2018)
- Neuroendocrinology
Ruohonen S, Valve L, Tuomainen K, Ailanen L, Röyttä M, Manz G, Baur N, Joos T, Savontaus E, Scheinin M
(A1 Refereed original research article in a scientific journal)
Metformin normalizes the structural changes in glycogen preceding prediabetes in mice overexpressing neuropeptide Y in noradrenergic neurons (2018)
- Pharmacology Research and Perspectives
Ailanen L, Bezborodkina NN, Virtanen L, Ruohonen ST, Malova AV, Okovityi SV, Chistyakova EY, Savontaus E
(A1 Refereed original research article in a scientific journal)
Partial thyrocyte-specific Gαs deficiency leads to rapid-onset hypothyroidism, hyperplasia, and papillary thyroid carcinoma-like lesions in mice (2018)
- FASEB Journal
Konrad Patyra, Holger Jaeschke, Christoffer Löf, Meeri Jännäri, Suvi T. Ruohonen, Henriette Undeutsch, Moosa Khalil, Andreina Kero, Matti Poutanen, Jorma Toppari, Min Chen, Lee S. Weinstein, Ralf Paschke, Jukka Kero
(A1 Refereed original research article in a scientific journal)
(2018)
- Frontiers in Pharmacology
Liisa Ailanen, Laura H. Vähätalo, Henriikka Salomäki-Myftari, Satu Mäkelä, Wendy Orpana, Suvi T. Ruohonen, Eriika Savontaus
(A1 Refereed original research article in a scientific journal)
The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update (2018)
Rewers M, Hyöty H, Lernmark Å, Hagopian W, She JX, Schatz D, Ziegler AG, Toppari J, Akolkar B, Krischer J
(A2 Refereed review article in a scientific journal )
Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease (2017)
- Scientific Reports
Jokela H, Hakkarainen J, Kätkänaho L, Pakarinen P, Ruohonen ST, Tena-Sempere M, Zhang FP, Poutanen M
(A1 Refereed original research article in a scientific journal)