Xiang-Guo Li
Associate Professor
Turku PET Centre, University of Turku xiali@utu.fi Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0002-9118-7223 |
Radiochemistry, Radiopharmaceuticals, PET imaging, New drug development
Radiochemistry, Radiopharmaceuticals, InFLAMES Flagship
I am a radiochemist and medicinal chemist working at Turku PET Centre, University of Turku, Finland. I received my PhD degree from the Institute of Biomedicine, Faculty of Medicine, University of Turku, in 2008. Then I was at a Post-doctoral position funded by the Academy of Finland during 2010-2012. I received my Docentship in 2012 from University of Turku. Since 2013, I have been working at Turku PET Centre. At present, I work as an Assistant Professor in Radiochemistry, and Principal Investigator in the InFLAMES Research Flagship.
Basic research in radiochemistry including methodological development for radiosynthesis and radiolabeling techniques. We have been able to radiolabel many types of molecules including small organic compounds, peptides, antibody and antibody fragments, oligonucleotides, oligosaccharides etc.
Development of new radiopharmaceuticals for PET imaging of inflammatory diseases and immunological diseases.
The radiolabeled molecules are for imaging diseases or for studying disease machanisms with PET.
I teach in the courses of Radiopharmaceutical Chemistry, Radiolabeling techniques, Measuring techniques in radiochemistry, PET Basics, and supervise BSc, MSc and PhD students.
- 2025
- ACS pharmacology & translational scienceSleep Medicine Reviews
(A1 Refereed original research article in a scientific journal) - Highlight selection of radiochemistry and radiopharmacy developments by editorial board (2025)
- EJNMMI Radiopharmacy and ChemistryEJNMMI Radiopharmacy and Chemistry
(Other publication) - (2025)
- European Journal of Pharmaceutical SciencesJournal of Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - Macrophage mannose receptor CD206-targeted PET imaging in experimental acute myocardial infarctionMacrophage mannose receptor CD206 targeting of fluoride‐18 labeled mannosylated dextran: A validation study in mice2025
- EJNMMI ResearchEuropean Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - (2025)
- EJNMMI Radiopharmacy and ChemistryCarbohydrate Research
(A1 Refereed original research article in a scientific journal) - (2025)
- Cardiovascular ResearchMolecular Pharmaceutics
(A1 Refereed original research article in a scientific journal) - The relationships between non-invasive myocardial work indices, myocardial blood flow and viability determined by PET (2025)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(Abstract) - Trajectories and determinants of myocardial work indices in patients with acute myocardial infarction after primary percutaneous coronary intervention (2025)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(Abstract) - (2025)
- Molecular PharmaceuticsMolecular Imaging and Biology
(A1 Refereed original research article in a scientific journal) - Analysis of sleep apnea research with a special focus on the use of positron emission tomography as a study tool (2024)
(A2 Refereed review article in a scientific journal ) - Evaluation of 18F FOL a PET tracer targeting folate receptor beta in a rat model of myocardial infarction (2024)
- European Heart Journal
(Abstract) - Highlight selection of radiochemistry and radiopharmacy developments by editorial board (2024)
(Other publication) - Imaging of Myocardial αvβ3Integrin Expression for Evaluation of Myocardial Injury After Acute Myocardial Infarction (2024)
(A1 Refereed original research article in a scientific journal) - (2024)
(A1 Refereed original research article in a scientific journal) - Mannose receptor independent uptake of transmembrane glycocluster immunostimulant TADM by macrophages (2024)
(A1 Refereed original research article in a scientific journal) - Switching the Chemoselectivity in the Preparation of [18F]FNA-N-CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3 (2024)
(A1 Refereed original research article in a scientific journal) - Voices in Molecular Pharmaceutics: Meet Professor Xiang-Guo Li, an Expert in Radiopharmaceutical Chemistry and Positron Emission Tomography for Improved Imaging of Immunological Disorders and Brain Tumors (2024)
- Molecular Pharmaceutics
(B1 Other refereed article (e.g., editorial, letter, comment) in a scientific journal) - Aluminum Fluoride-18 Labeled Mannosylated Dextran: Radiosynthesis and Initial Preclinical Positron Emission Tomography Studies (2023)
- Molecular Imaging and Biology
(A1 Refereed original research article in a scientific journal) - Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [68Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease (2023)
(A1 Refereed original research article in a scientific journal) - Efficient radiosynthesis of a new folate receptor-targeting PET tracer, [18F]fluoronicotinic acid labeled folate, for imaging lung fibrosis (2023)
- Nuclear Medicine and Biology
(Other publication)



