Tuomas Lönnberg
Professor, Ph.D.
tuanlo@utu.fi +358 29 450 3191 +358 50 308 5073 Office: K231 ORCID identifier: https://orcid.org/0000-0003-3607-3116 |
Areas of expertise
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
Publications 
8 of 10
- Hydrolytic Reactions of Nucleoside Phosphoramidates: Kinetics and Mechanisms (2010)
- Mini-Reviews in Organic Chemistry
(A2 Refereed review article in a scientific journal ) - Oxidation of an Oligonucleotide-Bound Ce-III/Multiphosphonate Complex for Site-Selective DNA Scission (2010)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - Phosphorane intermediate vs. leaving group stabilization by intramolecular hydrogen bonding in the cleavage of trinucleoside monophosphates: implications for understanding catalysis by the large ribozymes (2010)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - CARB 84-Elucidating the role of a hydrogen bond donor at the 2'-position of the 3'-linked departing nucleoside in transesterification by large ribozymes: Hydrolytic reactions of 2',3'-O-methyleneadenosin-5'-yl 5'-O-methyluridin-3'-yl 5'-O-methyl-2'-trifluoroacetamido-2'-deoxyuridin-3'-yl phosphate (2009)
- Abstracts of Papers of the American Chemical Society
(B3 Non-refereed article in a conference publication) - Human Telomeric DNA Sequence-Specific Cleaving by G-Quadruplex Formation (2009) Xu Y, Suzuki Y, Lonnberg T, Komiyama M
(A1 Refereed original research article in a scientific journal) - Bisphosphonate derivatives of nucleoside antimetabolites: Hydrolytic stability and hydroxyapatite adsorption of 5 '-beta,gamma-methylene and 5 '-beta,gamma-(1-hydroxyethylidene) triphosphates of 5-fluorouridine and ara-cytidine (2008)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Prompt site-selective DNA hydrolysis by Ce(IV)-EDTA using oligonucleotide multiphosphonate conjugates (2008)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Thio effects on the departure of the 3 '-linked ribonucleoside from diribonucleoside 3 ',3 '-phosphorodithioate diesters and triribonucleoside 3 ',3 ',5 '-phosphoromonothioate triesters: Implications for ribozyme catalysis (2007)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - A novel type of bisphosphonate conjugates for treating cancer induced bone diseases: In vitro and in vivo evidence (2006)
- Cancer Treatment Reviews
(A2 Refereed review article in a scientific journal ) - Hydrolytic stability of a phosphate-branched oligonucleotide incorporating a ribonucleoside 3 '-phosphotriester unit (2006)
- Nucleosides, Nucleotides and Nucleic Acids
(A1 Refereed original research article in a scientific journal)
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