Tuomas Lönnberg
Professor, Ph.D.
tuanlo@utu.fi +358 29 450 3191 +358 50 308 5073 Office: K231 ORCID identifier: https://orcid.org/0000-0003-3607-3116 |
Areas of expertise
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
Publications 
4 of 5
- Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences : The Pd2+ Complex of 2,6-bis(3,5-dimethylpyrazol-1-yl)purine Riboside (2012) Sharmin Taherpour, Tuomas Lönnberg
(A1 Refereed original research article in a scientific journal) - Mimics of small ribozymes utilizing a supramolecular scaffold (2012)
- Dalton Transactions
(A1 Refereed original research article in a scientific journal) - Thio effects as a tool for mechanistic studies of the cleavage of RNA phosphodiester bonds: the chemical basis (2012) From Nucleic Acid Sequences to Molecular Medicine Mikko Ora, Tuomas Lönnberg, Harri Lönnberg
(A3 Refereed book chapter or chapter in a compilation book) - Manipulation of Single-Stranded DNA by Using an Artificial Site-Selective DNA Cutter Composed of Cerium(IV)/EDTA and Phosphonate-Oligonucleotide Conjugates (2011)
- Chemistry - An Asian Journal
(A1 Refereed original research article in a scientific journal) - Metal ion chelates as surrogates of nucleobases for the recognition of nucleic acid sequences (2011) S Taherpour, T Lönnberg, J Arpalahti, H Lönnberg
(B3 Non-refereed article in a conference publication) - THE Zn2+ COMPLEX OF 1,4,7,10-TETRAAZACYCLODODECANE AS AN ARTIFICIAL NUCLEOBASE (2011)
- Nucleosides, Nucleotides and Nucleic Acids
(A1 Refereed original research article in a scientific journal) - Understanding Catalysis of Phosphate-Transfer Reactions by the Large Ribozymes (2011)
- Chemistry - A European Journal
(A2 Refereed review article in a scientific journal ) - Biodegradable protection of antiviral nucleoside 5´-phosphoramidates (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Leisvuori A, Aiba Y, Lönnberg T, Poijärvi-Virta P, Blatt L, Beigelman L, Lönnberg H
(B3 Non-refereed article in a conference publication) - Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5 '-monophosphates bearing a biodegradable protecting group (2010)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Effect of Secondary Structure on the Product Distribution of the Transesterification of Group I Introns (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Lönnberg T, Kero K-M
(B3 Non-refereed article in a conference publication) - Hydrolytic Reactions of Nucleoside Phosphoramidates: Kinetics and Mechanisms (2010)
- Mini-Reviews in Organic Chemistry
(A2 Refereed review article in a scientific journal ) - Oxidation of an Oligonucleotide-Bound Ce-III/Multiphosphonate Complex for Site-Selective DNA Scission (2010)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - Phosphorane intermediate vs. leaving group stabilization by intramolecular hydrogen bonding in the cleavage of trinucleoside monophosphates: implications for understanding catalysis by the large ribozymes (2010)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - CARB 84-Elucidating the role of a hydrogen bond donor at the 2'-position of the 3'-linked departing nucleoside in transesterification by large ribozymes: Hydrolytic reactions of 2',3'-O-methyleneadenosin-5'-yl 5'-O-methyluridin-3'-yl 5'-O-methyl-2'-trifluoroacetamido-2'-deoxyuridin-3'-yl phosphate (2009)
- Abstracts of Papers of the American Chemical Society
(B3 Non-refereed article in a conference publication) - Human Telomeric DNA Sequence-Specific Cleaving by G-Quadruplex Formation (2009)
- Journal of the American Chemical Society
(A1 Refereed original research article in a scientific journal) - Bisphosphonate derivatives of nucleoside antimetabolites: Hydrolytic stability and hydroxyapatite adsorption of 5 '-beta,gamma-methylene and 5 '-beta,gamma-(1-hydroxyethylidene) triphosphates of 5-fluorouridine and ara-cytidine (2008)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Prompt site-selective DNA hydrolysis by Ce(IV)-EDTA using oligonucleotide multiphosphonate conjugates (2008)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Thio effects on the departure of the 3 '-linked ribonucleoside from diribonucleoside 3 ',3 '-phosphorodithioate diesters and triribonucleoside 3 ',3 ',5 '-phosphoromonothioate triesters: Implications for ribozyme catalysis (2007)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - A novel type of bisphosphonate conjugates for treating cancer induced bone diseases: In vitro and in vivo evidence (2006)
- Cancer Treatment Reviews
(A2 Refereed review article in a scientific journal ) - Hydrolytic stability of a phosphate-branched oligonucleotide incorporating a ribonucleoside 3 '-phosphotriester unit (2006)
- Nucleosides, Nucleotides and Nucleic Acids
(A1 Refereed original research article in a scientific journal)
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