Tuomas Lönnberg
Professor, Ph.D.
tuanlo@utu.fi +358 29 450 3191 +358 50 308 5073 Office: K231 ORCID identifier: https://orcid.org/0000-0003-3607-3116 |
Areas of expertise
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
nucleic acids chemistry; metalated oligonucleotides; metal-mediated base pairing; phosphate-transfer reactions
Publications
- Thio effects as a tool for mechanistic studies of the cleavage of RNA phosphodiester bonds: the chemical basis (2012) From Nucleic Acid Sequences to Molecular Medicine Mikko Ora, Tuomas Lönnberg, Harri Lönnberg
(A3 Refereed book chapter or chapter in a compilation book) - Manipulation of Single-Stranded DNA by Using an Artificial Site-Selective DNA Cutter Composed of Cerium(IV)/EDTA and Phosphonate-Oligonucleotide Conjugates (2011)
- Chemistry - An Asian Journal
(A1 Refereed original research article in a scientific journal) - Metal ion chelates as surrogates of nucleobases for the recognition of nucleic acid sequences (2011) S Taherpour, T Lönnberg, J Arpalahti, H Lönnberg
(B3 Non-refereed article in a conference publication) - THE Zn2+ COMPLEX OF 1,4,7,10-TETRAAZACYCLODODECANE AS AN ARTIFICIAL NUCLEOBASE (2011)
- Nucleosides, Nucleotides and Nucleic Acids
(A1 Refereed original research article in a scientific journal) - Understanding Catalysis of Phosphate-Transfer Reactions by the Large Ribozymes (2011)
- Chemistry - A European Journal
(A2 Refereed review article in a scientific journal ) - Biodegradable protection of antiviral nucleoside 5´-phosphoramidates (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Leisvuori A, Aiba Y, Lönnberg T, Poijärvi-Virta P, Blatt L, Beigelman L, Lönnberg H
(B3 Non-refereed article in a conference publication) - Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5 '-monophosphates bearing a biodegradable protecting group (2010)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Effect of Secondary Structure on the Product Distribution of the Transesterification of Group I Introns (2010) Proceedings of the XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids Lönnberg T, Kero K-M
(B3 Non-refereed article in a conference publication) - Hydrolytic Reactions of Nucleoside Phosphoramidates: Kinetics and Mechanisms (2010)
- Mini-Reviews in Organic Chemistry
(A2 Refereed review article in a scientific journal ) - Oxidation of an Oligonucleotide-Bound Ce-III/Multiphosphonate Complex for Site-Selective DNA Scission (2010)
- Chemistry - A European Journal
(A1 Refereed original research article in a scientific journal) - Phosphorane intermediate vs. leaving group stabilization by intramolecular hydrogen bonding in the cleavage of trinucleoside monophosphates: implications for understanding catalysis by the large ribozymes (2010)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Hydrolytic stability of 2 ',3 '-O-methyleneadenos-5 '-yl 2 ',5 '-di-O-methylurid-3 '-yl 5 '-O-methylurid-3 '(2 ')-yl phosphate: implications to feasibility of existence of phosphate-ranched RNA under physiological conditions (2005)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - Hydrolysis of 2 ',3 '-O-methyleneadenos-5 '-yl bis(2 ',5 '-di-O-methylurid-3 '-yl) phosphate, a sugar O-alkylated trinucleoside 3 ',3 ',5 '-monophosphate: Implications for the mechanism of large ribozymes (2004)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal)