Leena Kainulainen
leena.kainulainen@utu.fi |
paediatrics; immunodeficiency; paediatric infectious diseases; respiratory infections; rhinovirus
Docent
Leena Kainulainen graduated from medical school in 1995(University of Turku)
and defended her PhD theses on CVID in 2000. She received specialist licence in
paediatrics in 2005 and in pediatric infectious diseases 2013 and was appointed
as a docent in paediatrics in 2013 (University of Turku). She is currently
working as Head of the Division of Pediatric Care in Turku University Hospital
and as an immunology consultant at Department of Pediatrics and Medicine at
Turku University Hospital. She participates in neonatal screening for
severe immunodeficiencies.
Docent
Kainulainen´s research is focused on
primary immunodeficiency. Her current research interests comprise rhinovirus
infections in primary hypogammaglobulinemia patients. Clinical trial on the
treatment of rhinovirus infection with pegylated interferon alfa in CVID
patients is ongoing. Research project on innate immunity in autoimmune patients
is ongoing. In addition, she participates in research project aiming at evaluating immunological status in pediatric
patients with neonatal cardiac surgery.
Docent
Kainulainen has been working as a clinical lecturer in pediatrics 2004 and
2006. Currently she teaches regularly medical students and paediatric residents
as a part of her clinical duties.
- T cell immunity following COVID-19 vaccination in adult patients with primary antibody deficiency - a 22-month follow-up (2023)
- Frontiers in immunology
(A1 Refereed original research article in a scientific journal) - Low pre-vaccination SARS-CoV-2 seroprevalence in Finnish health care workers: a prospective cohort study (2022)
- Infectious Diseases
(A1 Refereed original research article in a scientific journal) - STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation (2022)
- Immunity
(A1 Refereed original research article in a scientific journal) - Clinical, functional and genetic characterization of 16 patients suffering from chronic granulomatous disease variants - identification of 11 novel mutations in CYBB (2021)
- Clinical and Experimental Immunology
(A1 Refereed original research article in a scientific journal) - Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child (2021)
- Nature Medicine
(A1 Refereed original research article in a scientific journal) - Multibatch Cytometry Data Integration for Optimal Immunophenotyping (2021)
- Journal of Immunology
(A1 Refereed original research article in a scientific journal) - Increased antiviral response in circulating lymphocytes from hypogammaglobulinemia patients (2020)
- Allergy
(A1 Refereed original research article in a scientific journal) - The Safety and Efficacy of Live Viral Vaccines in Patients With Cartilage-Hair Hypoplasia (2020)
- Frontiers in immunology
(A1 Refereed original research article in a scientific journal) - Tavallinen infektiokierre (2019) Lasten infektiosairaudet Ville Peltola, Leena Kainulainen
(D2 Article in a professional compilation book) - Suomi on synnynnäisten immuunivajeiden maa (2018)
- Duodecim
(D1 Article in a professional journal)



