Taija Heinosalo

- Senior Research Fellow,
Institute of Biomedicine (Faculty of Medicine)
- Docent,

tsalon@utu.fi

Consistent and effective method to define the mouse estrous cycle stage by a deep learning-based model (2024)
- Journal of Endocrinology
Strauss, Leena; Junnila, Arttu; Wärri, Anni; Manti, Maria; Jiang, Yiwen; Löyttyniemi, Eliisa; Stener-Victorin, Elisabet; Lagerquist, Marie K.; Kukoricza, Krisztina; Heinosalo, Taija; Blom, Sami; Poutanen, Matti
Serum Hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein a but does not serve as an independent marker for preeclampsia (2024)
- Biology of Reproduction
Heinosalo, Taija; Saarinen, Niina; Biehl, Alexander; Rytkönen, Kalle T; Villa, Pia M; Juhila, Juuso; Koskimies, Pasi; Laiho, Asta; Hämäläinen, Esa; Kajantie, Eero; Räikkönen, Katri; Elo, Laura L; Laivuori, Hannele; Poutanen, Matti
Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expression (2023)
- BMC Medicine
Marla Sushma, Mortlock Sally, Heinosalo Taija, Poutanen Matti, Montgomery Grant W., Mckinnon Brett David
Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis (2022)
- iScience
Rytkönen Kalle T, Faux Thomas, Mahmoudian Mehrad, Heinosalo Taija, Nnamani Maurice C, Perheentupa Antti, Poutanen Matti, Elo Laura L, Wagner Günter P
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice (2022)
- International Journal of Molecular Sciences
Heinosalo Taija, Rytkönen Kalle T., Saarinen Niina, Järvensivu Päivi, Damdimopoulou Pauliina, Strauss Leena, Orasniemi Satu, Horshauge Petricia, Gabriel Michael, Koskimies Pasi, Ohlsson Claes, Kronqvist Pauliina, Poutanen Matti
A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions (2020)
- Scientific Data
Gabriel M, Fey V, Heinosalo T, Adhikari P, Rytkönen K, Komulainen T, Huhtinen K, Laajala TD, Siitari H, Virkki A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M
Exploratory Analysis of CA125-MGL and –STn Glycoforms in the Differential Diagnostics of Pelvic Masses (2020)
- The Journal of Applied Laboratory Medicine
Liina Salminen, Nimrah Nadeem, Anne Lone Rolfsen, Anne Dørum, Teemu D Laajala, Seija Grènman, Sakari Hietanen, Taija Heinosalo, Antti Perheentupa, Matti Poutanen, Nils Bolstad, Olli Carpén, Urpo Lamminmäki, Kim Pettersson, Kamlesh Gidwani, Johanna Hynninen, Kaisa Huhtinen
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells (2020)
- Reproduction
Rytkönen KT, Heinosalo T, Mahmoudian M, Ma X, Perheentupa A, Elo LL, Poutanen M, Wagner GP
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources (2019)
- The Journal of Applied Laboratory Medicine
Gidwani K, Nadeem N, Huhtinen K, Kekki H, Heinosalo T, Hynninen J, Perheentupa A, Poutanen M, Carpen O, Pettersson K, Lamminmäki U
Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells (2019)
- European Urology
Kimmo Kettunen, Peter J. Boström, Tarja Lamminen, Taija Heinosalo, Gun West , Irena Saarinen, Katja Kaipio, Juha Rantala, Chris Albanese, Matti Poutanen, Pekka Taimen
Role of hydroxysteroid (17beta) dehydrogenase type 1 in reproductive tissues and hormone-dependent diseases (2019)
- Molecular and Cellular Endocrinology
Heinosalo T., Saarinen N., Poutanen M.
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue (2018)
- Journal of Pharmaceutical and Biomedical Analysis
Häkkinen MR, Heinosalo T, Saarinen N, Linnanen T, Voutilainen R, Lakka T, Jääskeläinen J, Poutanen M, Auriola S
HSD17B1 expression induces inflammation-aided rupture of mammary gland myoepithelium (2018)
- Endocrine-Related Cancer
Päivi Järvensivu, Taija Heinosalo, Janne Hakkarainen, Pauliina Kronqvist, Niina Saarinen, Matti Poutanen
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis (2018)
- Human Reproduction
Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala TD, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M
HSD17B1 expression enhances estrogen signaling stimulated by the low active estrone, evidenced by an estrogen responsive element-driven reporter gene in vivo (2015)
- Chemico-Biological Interactions
Jarvensivu P, Saloniemi-Heinonen T, Awosanya M, Koskimies P, Saarinen N, Poutanen M
Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions (2014)
- Journal of Clinical Endocrinology and Metabolism
Huhtinen K, Saloniemi-Heinonen T, Keski-Rahkonen P, Desai R, Laajala D, Ståhle M, Häkkinen M, Laajala D, Suvitie P, Awosanya M, Aittokallio T, Handelsman D, Auriola S, Perheentupa A, Poutanen M.
Ovarian Endometriosis Signatures Established through Discovery and Directed Mass Spectrometry Analysis (2014)
- Journal of Proteome Research
Vehmas AP, Muth-Pawlak D, Huhtinen K, Saloniemi-Heinonen T, Jaakkola K, Laajala TD, Kaprio H, Suvitie PA, Aittokallio T, Siitari H, Perheentupa A, Poutanen M, Corthals GL
In vivo mouse model for analysis of hydroxysteroid (17beta) dehydrogenase 1 inhibitors (2009)
- Molecular and Cellular Endocrinology
Lamminen T, Saloniemi T, Huhtinen K, Koskimies P, Messinger J, Husen B, Thole H, Poutanen M
Activation of androgens by hydroxysteroid (17beta) dehydrogenase 1 in vivo as a cause of prenatal masculinization and ovarian benign serous cystadenomas (2007)
- Molecular Endocrinology -Baltimore-
Saloniemi T, Lamminen T, Huhtinen K, Welsh M, Saunders P, Kujari H, Poutanen M
Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts (2006)
- Endocrinology
Husen B, Huhtinen K, Saloniemi T, Messinger J, Thole HH, Poutanen M