Juho Joutsa
MD, PhD, Professor of Neurology
Turku Brain and Mind Center jtjout@utu.fi Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0002-3457-9415 |
Neurology, Movement disorders, Neuroimaging, Brain stimulation
Professor of Neurology, Clinical Neurosciences, University of Turku, 2023-
Chief neurologist, Neurocenter, Turku University Hospital, 2023-
Associate Professor, Neuroimaging, Turku Brain and Mind Center, University of Turku, 2022-2023
Assistant Professor, Neuroimaging, Turku Brain and Mind Center, University of Turku, 2019-2022
Specialist in Neurology, University on Turku, 2020
Postdoctoral Researcher (Academy of Finland) 2016-2019
Research Fellow, Massachusetts General Hospital and Harvard Medical School, 2016-2018
Adjunct Professor, Department of Neurology University of Turku, 2015-
PhD, University of Turku, 2012
MD, University of Turku, 2009
Currently, I work as Professor of Neurology at University of Turku and chief neurologist at Turku University Hospital. I lead Brain Stimulation and Neuroimaging laboratory at University of Turku (www.turkubrainlab.fi) and act as the chair of Turku Brain and Mind Center.
My research work focuses on investigating the neurobiological mechanisms of brain disorders and development of new treatment options using neuromodulation techniques. I am interested in a wide spectrum of brain disorders but especially neurological movement disorders and addictions. Our lab uses multimodal approach, combining causal brain lesions, state-of-the-art brain imaging technologies (MRI, PET, SPECT) and neuromodulation techniques (TMS, DBS, MRgFUS).
10 representative publications:
Liesmäki O, Kungshamn J, Likitalo O, Ellis EG, Bellmunt-Gil A, Aaltonen J, Steinweg I, Myller EM, Roine S, Friedrich MU, Ylikotila P, Joutsa J. Localization and network connectivity of lesions causing limb ataxia in patients with stroke. Neurology 2024;103(6)
Theys C, Jaakkola E, Melzer TR, De Nil LF, Guenther FH, Cohen AL, Fox MD, Joutsa J. Localization of stuttering based on causal brain lesions. Brain 2024;147(6):2203-13.
Honkanen EA, Rönkä J, Pekkonen E, Aaltonen J, Koivu M, Eskola O, Eldebakey H, Volkmann J, Kaasinen V, Reich MM, Joutsa J. GPi-DBS induced brain metabolic activation in cervical dystonia. J Neurol Neurosurg Psychiatry, 2024;95(4):300-8.
Joutsa J, Lipsman N, Horn A, Cosgrove GR, Fox MD. The return of the lesion for localization and therapy. Brain 2023;146(8):3146-55.
Corp DT, Greenwood C, Morrison-Ham J, Pullinen J, McDowall G, Younger E, Jinnah H, Fox MD, Joutsa J. Clinical and structural findings in patients with lesion-induced dystonia: descriptive and quantitative analysis of all published cases. Neurology 2022;99(18):1957-67.
Joutsa J, Moussawi K, Siddiqi S et al. Brain lesion disrupting addiction map to a common human brain circuit. Nature Medicine 2022;28:1249-55.
Joutsa J, Shih LC, Fox MD. Mapping Holmes’ tremor circuit using the human brain connectome. Ann Neurol 2019;86(6):812-20.
Joutsa J, Horn A, Hsu J, Fox MD. Localization of parkinsonism based on focal brain lesions. Brain 2018;141(8):2445-56.
Joutsa J, Shih LC, Horn A, Reich MM, Wu O, Rost N, Fox MD. Identifying therapeutic targets from spontaneous beneficial brain lesions. Ann Neurol. 2018;84(1):153-7.
Joutsa J, Rinne JO, Hermann B, Karrasch M, Anttinen A, Shinnar S, Sillanpää M. Association between childhood-onset epilepsy and amyloid burden 5 decades later. JAMA Neurology 2017;74(5):583-90.
Lead teacher in neurology, M.D. curriculum
- Decreased mu-opioid receptor binding in pathologycal gambling: A PET study with [11C]carfentanil (2015)
- Journal of Cerebral Blood Flow and Metabolism
(Other publication) - Dopaminergic function and intertemporal choice (2015)
- Translational Psychiatry
(A1 Refereed original research article in a scientific journal) - Dorsal-to-Ventral Shift in Midbrain Dopaminergic Projections and Increased Thalamic/Raphe Serotonergic Function in Early Parkinson Disease (2015)
- Journal of Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - Effects of aging and gender on striatal and extrastriatal [I-123]FP-CIT binding in Parkinson's disease (2015)
- Neurobiology of Aging
(A1 Refereed original research article in a scientific journal) - Hypermetabolism of olivary nuclei in a patient with progressive ataxia and palatal tremor. (2015)
- Tremor and Other Hyperkinetic Movements
(A1 Refereed original research article in a scientific journal) - Is Occipital Cortex a Valid Reference Region in I-123-FP-CIT SPECT Imaging? (2015)
- Clinical Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - Kävelyhäiriö on vaskulaarisen parkinsonismin ilmentymä (2015)
- Duodecim
(D1 Article in a professional journal) - Long-Term Interrelationship between Brain Metabolism and Amyloid Deposition in Mild Cognitive Impairment (2015)
- Journal of Alzheimer's Disease
(A1 Refereed original research article in a scientific journal) - Long-term test-retest reliability of striatal and extrastriatal dopamine D-2/3 receptor binding: study with [C-11]raclopride and high-resolution PET (2015)
- Journal of Cerebral Blood Flow and Metabolism
(A1 Refereed original research article in a scientific journal) - Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [(18)F]FEMPA in Alzheimer's disease patients and control subjects. (2015)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - Vagusstimulaattorin aiheuttama unenaikainen hengityshäiriö (2015)
- Duodecim
(A1 Refereed original research article in a scientific journal) - Akinetic crisis in Parkinson's disease is associated with a severe loss of striatal dopamine transporter function: a report of two cases. (2014)
- Case Reports in Neurology
(A1 Refereed original research article in a scientific journal) - Diagnostic accuracy of parkinsonism syndromes by general neurologists (2014)
- Parkinsonism and Related Disorders
(A1 Refereed original research article in a scientific journal) - Differences in striatal dopamine transporter density between tremor dominant and non-tremor Parkinson's disease. (2014)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - DRD2-related TaqIA genotype is associated with dopamine release during a gambling task (2014)
- Journal of Addiction Medicine
(A1 Refereed original research article in a scientific journal) - Impulse control disorders are associated with multiple psychiatric symptoms in Parkinson's disease (2014)
- Journal of Parkinson's Disease
(A1 Refereed original research article in a scientific journal) - Miksi pappa ei päässyt ruokasaliin? (2014)
- Duodecim
(D1 Article in a professional journal) - Striatal volume is related to phonemic verbal fluency but not to semantic or alternating verbal fluency in early Parkinson's disease (2014)
- Journal of Neural Transmission
(A1 Refereed original research article in a scientific journal) - Brain Volumetric Correlates of Memory in Early Parkinson's Disease (2013)
- Journal of Parkinson's Disease
(A1 Refereed original research article in a scientific journal) - Etenevän parapareesin harvinaisia syitä (2013)
- Duodecim
(A1 Refereed original research article in a scientific journal)