Sirpa Pahkuri - UTU Research Portal

Sirpa Pahkuri

Institute of Biomedicine (Faculty of Medicine)

sielpa@utu.fi

Publications

DNA methylation as a mediator of genetic and environmental factors in type 1 diabetes and autoimmunity (2026) Pahkuri, Sirpa
(G5 Article dissertation )
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies (2024)
- Nature Communications
Starskaia, Inna; Valta, Milla; Pietilä, Sami; Suomi, Tomi; Pahkuri, Sirpa; Kalim, Ubaid Ullah; Rasool, Omid; Rydgren, Emilie; Hyöty, Heikki; Knip, Mikael; Veijola, Riitta; Ilonen, Jorma; Toppari, Jorma; Lempainen, Johanna; Elo, Laura L.; Lahesmaa, Riitta
(A1 Refereed original research article in a scientific journal)
The effect of type 1 diabetes protection and susceptibility associated HLA class II genotypes on DNA methylation in immune cells (2024)
- HLA
Pahkuri, Sirpa; Katayama, Shintaro; Valta, Milla; Nygård, Lucas; Knip, Mikael; Kere, Juha; Ilonen, Jorma; Lempainen, Johanna; Finnish Pediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls (2023)
- Autoimmunity
Pahkuri Sirpa, Ekman Ilse, Vandamme Céline, Näntö-Salonen Kirsti, Toppari Jorma, Veijola Riitta, Knip Mikael, Kinnunen Tuure, Ilonen Jorma, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)
Viral infection-related gene upregulation in monocytes in children with signs of β-cell autoimmunity (2022)
- Pediatric Diabetes
Valta Milla, Yoshihara Masahito, Einarsdottir Elisabet, Pahkuri Sirpa, Ezer Sini, Katayama Shintaro, Knip Mikael, Veijola Riitta, Toppari Jorma, Ilonen Jorma, Kere Juha, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)