Sami Ventelä - UTU Research Portal

Sami Ventelä

- ,
- Senior Researcher,
Turku Bioscience Centre (Independent units)
- Docent,
Department of Clinical Medicine (Faculty of Medicine)

Turku Centre for Biotechnology

satuve@utu.fi

: https://orcid.org/0000-0001-6672-6662

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Pan-cancer ex vivo target evaluation of phosphodiesterase 3 A (PDE3A) (2026)
- Journal of Molecular Medicine
Rice, Kiesha; Lehtinen, Noora; Välimäki, Eetu; Suhonen, Janne; Taimen, Pekka; Kettunen, Kimmo; Ventelä, Sami; Kononen, Juha; Sihto, Harri; Rantala, Juha K.
Restoring the tumour mechanophenotype of vocal fold cancer reverts its malignant propertiesDiverse oncogenes use common mechanisms to drive growth of major forms of human cancer (2026)
- Nature Materials
Kaivola, Jasmin; Punovuori, Karolina; Chastney, Megan R.; Abdo, Hind; Follain, Gautier; Mathieu, Mathilde; Joshi, Omkar; Miroshnikova, Yekaterina A.; Krautgasser, Fabian; Di Franco, Jasmin; Conway, James R. W.; Held, Sofia; Bertillot, Fabien; Hagström, Jaana; Mäkitie, Antti; Irjala, Heikki; Ventelä, Sami; Hamidi, Hellyeh; Scita, Giorgio; Cerbino, Roberto; Wickström, Sara A.; Ivaska, Johanna
Spatial single-cell analysis reveals tumor microenvironment signatures predictive of oral cavity cancer outcome (2026)
- Cell Reports MedicineScience Advances
Näsiaho, Joni; Nissi, Linda; Ventelä, Sami; Irjala, Heikki; Salmi, Marko
Added value of HPV-DNA in situ hybridization as an adjunct to p16 Immunohistochemistry in oropharyngeal squamous cell carcinoma (2025)
- Acta Oto-Laryngologica
Nissi, Linda; Huusko, Teemu; Routila, Johannes; Vaittinen, Samuli; Leivo, Ilmo; Irjala, Heikki; Ventela, Sami
Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma (2025)
Kauko, Otto; Turunen, Mikko; Pihlajamaa, Päivi; Häkkinen, Antti; Queiroz, Rayner M. L.; Pääkkönen, Mirva; Ventelä, Sami; Gaetani, Massimiliano; Lundström, Susanna L.; Murgia, Antonio; Sahu, Biswajyoti; Routila, Johannes; Wei, Gong-Hong; Irjala, Heikki; Griffin, Julian L.; Lilley, Kathryn S.; Kivioja, Teemu; Hautaniemi, Sampsa; Taipale, Jussi
(2025)
- Cancer Medicine
Routila, Erica; Salminen, Sadie; Mahran, Randa; Toriseva, Mervi; Irjala, Heikki; Haapio, Eeva; Kytö, Eero; Ventelä, Sami; Pettersson, Kim; Routila, Johannes; Gidwani, Kamlesh; Leivo, Janne
Histological tumor necrosis predicts decreased survival after neoadjuvant chemotherapy in head and neck squamous cell carcinoma (2025)
- Oral Oncology
Koskenniemi, A.R.; Huusko, T.; Routila, J.; Jalkanen, S.; Hollmén, M.; Vainio, P.; Ventelä, S.
LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancerMultiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer (2025)
- Embo molecular medicine
Qiao, Xi; Routila, Johannes; Tienhaara, Mari; Irjala, Heikki; Santhi, Priyadharshini Parimelazhagan; Huusko, Teemu; Nissi, Linda; Paatero, Ilkka; Lehtinen, Noora; Rantala, Juha; Viljanen, Toni; Leivo, Ilmo; Koivunen, Petri; Jouppila-Matto, Anna; Taulu, Rami; Back, Leif; Wilkman, Tommy; Haapio, Eeva; Kinnunen, Ilpo; Kurppa, Kari; Westermarck, Jukka; Ventelä, Sami
Risk of early death after treatment with curative intent for head and neck squamous cell carcinoma: a retrospective population-based study (2025)
- Acta Oncologica
Bazina, Mahmoud; Nikkilä, Rayan; Haapaniemi, Aaro; Bäck, Leif; Ventelä, Sami; Mäkitie, Antti
Sinonasal adenoid cystic carcinomas accompanied by seromucinous hamartoma and/or atypical sinonasal glands arising from seromucinous hamartoma: insight into their histogenesisAssessment of targeted therapy opportunities in sinonasal cancers using patient-derived functional tumor models (2025)
- Virchows Archiv
Bradova, Martina; Agaimy, Abbas; Laco, Jan; Martinek, Petr; Ing, Stanislav Kormunda; Badoual, Cecile; Damjanov, Ivan; Leivo, Ilmo; Bacchi, Carlos E.; Comperat, Eva; Ihrler, Stephan; Rupp, Niels J.; Sima, Radek; Steiner, Petr; Vanecek, Tomas; Mueller, Sarina; Ventelä, Sami; Skalova, Alena; Michal, Michal
2024
- Translational Oncology
Lehtinen, Noora; Suhonen, Janne; Rice, Kiesha; Välimäki, Eetu; Toriseva, Mervi; Routila, Johannes; Halme, Perttu; Rahi, Melissa; Irjala, Heikki; Leivo, Ilmo; Kallajoki, Markku; Nees, Matthias; Kuopio, Teijo; Ventelä, Sami; Rantala, Juha K.
Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth (2024)
- Cell Reports
Olotu, Opeyemi; Koskenniemi, Anna-Riina; Ma, Lin; Paramonov, Valeriy; Laasanen, Sini; Louramo, Elina; Bourgery, Matthieu; Lehtiniemi, Tiina; Laasanen, Samuli; Rivero-Müller, Adolfo; Löyttyniemi, Eliisa; Sahlgren, Cecilia; Westermarck, Jukka; Ventelä, Sami; Visakorpi, Tapio; Poutanen, Matti; Vainio, Paula; Mäkelä, Juho-Antti; Kotaja, Noora
Identification of stemness-related glycosylation changes in head and neck squamous cell carcinoma (2024)
- BMC Cancer
Routila, Erica; Mahran, Randa; Salminen, Seppo; Irjala, Heikki; Haapio, Eeva; Kytö, Eero; Ventelä, Sami; Petterson, Kim; Routila, Johannes; Gidwani, Kamlesh; Leivo, Janne
(2024)
- CellFrontiers in Oncology
Punovuori, Karolina; Bertillot, Fabien; Miroshnikova, Yekaterina A.; Binner, Mirjam I.; Myllymäki, Satu-Marja; Follain, Gautier; Kruse, Kai; Routila, Johannes; Huusko, Teemu; Pellinen, Teijo; Hagström, Jaana; Kedei, Noemi; Ventelä, Sami; Mäkitie, Antti; Ivaska, Johanna; Wickström, Sara A.
(2024)
- Virchows ArchivCancer MedicineOral Oncology
Pakkanen Pihla, Ilmarinen Taru, Halme Elina, Irjala Heikki, Koivunen Petri, Pukkila Matti, Ventelä Sami, Almangush Alhadi, Birkman Eva-Maria, Lindgren Outi, Pohjolainen Virva, Sjöblom Nelli, Haglund Caj, Hagström Jaana, Aaltonen Leena-Maija
xCT as a Predictor for Survival in a Population‐Based Cohort of Head and Neck Squamous Cell CarcinomaCisplatin overcomes radiotherapy resistance in OCT4-expressing head and neck squamous cell carcinoma (2024)
Nissi, Linda; Tuominen, Sanni; Routila, Johannes; Huusko, Teemu; Ketonen, Petra; Sundvall, Maria; Leivo, Ilmo; Irjala, Heikki; Minn, Heikki; Grönroos, Tove J.; Ventelä, Sami
Prognostic histological markers in oral tongue squamous cell carcinoma patients treated with (chemo)radiotherapy (2023)
- APMIS
Hyytiäinen Aini, Mroueh Rayan, Peltonen Johanna, Wennerstrand Pia, Mäkitie Antti, Al-Samadi Ahmed, Ventelä Sami, Salo Tuula
The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing (2023)
- Cancer Cell International
Hyytiäinen Aini, Korelin Katja, Toriseva Mervi, Wilkman Tommy, Kainulainen Satu, Mesimäki Karri, Routila Johannes, Ventelä Sami, Irjala Heikki, Nees Matthias, Al-Samadi Ahmed, Salo Tuula
TSPO is a potential independent prognostic factor associated with cellular respiration and p16 in head and neck squamous cell carcinoma (2023)
Tuominen Sanni, Nissi Linda, Kukkula Antti, Routila Johannes, Huusko Teemu, Leivo Ilmo, Minn Heikki, Irjala Heikki, Löyttyniemi Eliisa, Ventelä Sami, Sundvall Maria, Grönroos Tove J.
(2022)
Routila Johannes, Qiao Xi, Weltner Jere, Rantala Juha K, Carpén Timo, Hagström Jaana, Mäkitie Antti, Leivo Ilmo, Ruuskanen Miia, Söderlund Jenni, Rintala Marjut, Hietanen Sakari, Irjala Heikki, Minn Heikki, Westermarck Jukka, Ventelä Sami