A1 Journal article – refereed
Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2

List of Authors: Eskelinen EL, Cuervo AM, Taylor MRG, Nishino I, Blum JS, Dice JF, Sandoval IV, Lippincott-Schwartz J, August JT, Saftig P
Publication year: 2005
Journal: Traffic
Journal name in source: TRAFFIC
Journal acronym: TRAFFIC
Volume number: 6
Number of pages: 4
ISSN: 1398-9219

The present nomenclature of the splice variants of the lysosome-associated membrane protein type 2 (LAMP-2) is confusing. The LAMP-2a isoform is uniformly named in human, chicken, and mouse, but the LAMP-2b and LAMP-2c isoforms are switched in human as compared with mouse and chicken. We propose to change the nomenclature of the chicken and mouse b and c isoforms to agree with that currently used for the human isoforms. To avoid confusion in the literature, we further propose to adopt the use of capital letters for the updated nomenclature of all the isoforms in all three species: LAMP-2A, LAMP-2B, and LAMP-2C.

Last updated on 2019-20-07 at 15:36