A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2
Tekijät: Eskelinen EL, Cuervo AM, Taylor MRG, Nishino I, Blum JS, Dice JF, Sandoval IV, Lippincott-Schwartz J, August JT, Saftig P
Kustantaja: WILEY-BLACKWELL
Julkaisuvuosi: 2005
Journal: Traffic
Tietokannassa oleva lehden nimi: TRAFFIC
Lehden akronyymi: TRAFFIC
Vuosikerta: 6
Numero: 11
Aloitussivu: 1058
Lopetussivu: 1061
Sivujen määrä: 4
ISSN: 1398-9219
DOI: https://doi.org/10.1111/j.1600-0854.2005.00337.x
Tiivistelmä
The present nomenclature of the splice variants of the lysosome-associated membrane protein type 2 (LAMP-2) is confusing. The LAMP-2a isoform is uniformly named in human, chicken, and mouse, but the LAMP-2b and LAMP-2c isoforms are switched in human as compared with mouse and chicken. We propose to change the nomenclature of the chicken and mouse b and c isoforms to agree with that currently used for the human isoforms. To avoid confusion in the literature, we further propose to adopt the use of capital letters for the updated nomenclature of all the isoforms in all three species: LAMP-2A, LAMP-2B, and LAMP-2C.
The present nomenclature of the splice variants of the lysosome-associated membrane protein type 2 (LAMP-2) is confusing. The LAMP-2a isoform is uniformly named in human, chicken, and mouse, but the LAMP-2b and LAMP-2c isoforms are switched in human as compared with mouse and chicken. We propose to change the nomenclature of the chicken and mouse b and c isoforms to agree with that currently used for the human isoforms. To avoid confusion in the literature, we further propose to adopt the use of capital letters for the updated nomenclature of all the isoforms in all three species: LAMP-2A, LAMP-2B, and LAMP-2C.
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