A1 Refereed original research article in a scientific journal

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion



Authors: Santio NM, Vahakoski RL, Rainio EM, Sandholm JA, Virtanen SS, Prudhomme M, Anizon F, Moreau P, Koskinen PJ

Publisher: BIOMED CENTRAL LTD

Publication year: 2010

Journal: Molecular Cancer

Journal name in source: MOLECULAR CANCER

Journal acronym: MOL CANCER

Article number: ARTN 279

Volume: 9

Number of pages: 13

ISSN: 1476-4598

DOI: https://doi.org/10.1186/1476-4598-9-279

Self-archived copy’s web address: https://research.utu.fi/converis/portal/Publication/1643758


Abstract
Conclusions: Altogether, our data indicate that DHPCC-9 is not only a powerful tool to investigate physiological effects of the oncogenic Pim family kinases, but also an attractive molecule for drug development to inhibit invasiveness of Pim-overexpressing cancer cells.

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Last updated on 2024-26-11 at 16:15