Publications (92)
Publication type
areas
- Catalytically significant macrochelate formation in Zn2+ promoted hydrolysis of oligoribonucleotides: Model studies with chimeric phosphodiester/methylphosphonate oligomers
(1998)
- Nucleosides & nucleotides
- Kinetics and mechanisms for the cleavage and isomerization of the phosphodiester bonds of RNA by Bronsted acids and bases
(1998)
- Chemical Reviews
- Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2 '-O-methylribooligonucleotides
(1998)
- Nucleic Acids Research
- Bimetallic Ca2+ and Zn2+ complexes of BISDIEN: Potential catalysts of RNA cleavage
(1999)
- Collection Symposium Series
- Reactions of adenosine with bromo- and chloromalonaldehydes in aqueous solutions: Kinetics and mechanism
(1999)
- Nucleosides & nucleotides
- The Cu2+-promoted cleavage of mRNA 5 '-cap analogs: A kinetic study with P-1-(7-methylguanosin-5 '-yl) P-3-(nucleosid-5 '-yl) triphospates and P-1-(7-methylguanosin-5 '-yl) P-4-(guanosin-5 '-yl) tetraphosphate
(1999)
- Nucleosides & nucleotides
- The mechanism of the metal ion promoted cleavage of RNA phosphodiester bonds involves a general acid catalysis by the metal aquo ion on the departure of the leaving group
(1999)
- Royal Society of Chemistry. Journal: Perkin Transactions 2
- Zn2+ promoted hydrolysis of RNA
(1999)
- Nucleosides & nucleotides
- Cleavage of the phosphodiester bond of uridylyl-(3 ',5 ')-8-carboxymethylaminoadenosine by hydronium, hydroxide and zinc(II) ions: A model study aimed at elucidating the potential of a carboxylate function as an intramolecular catalyst
(2000)
- Nucleosides, Nucleotides and Nucleic Acids
- Reactions of adenosine with bromo- and chloromalonaldehydes in aqueous solution: Kinetics and mechanism
(2000)
- European Journal of Organic Chemistry
- Synthesis of 2,6,10,14,18,22-hexaazaspiro[11.11]tricosane, the first example of a spiro aza crown derived from 2,2-bis(aminomethyl)propane-1,3-diamine
(2001)
- Tetrahedron Letters
- The cleavage of phosphodiester bonds within small RNA bulges in the presence and absence of metal ion catalysts
(2001)
- Journal of the Chemical Society, Perkin Transactions 2
- The effect of secondary structure on cleavage of the phosphodiester bonds of RNA
(2001)
- Cell Biochemistry and Biophysics
- A comparative study on the cleavage of stereoisomeric uridylyl(3 ',5 ')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts
(2002)
- Origins of Life and Evolution of Biospheres
- Azacrown tethered oligonucleotides: Potential artificial RNases
(2002)
- Collection Symposium Series
- Cleavage and isomerization of RNA phosphodiester bonds: Nucleoside phosphotriesters and chimeric ribo/2 '-O-methylribo oligonucleotides as tools for mechanistic studies
(2002)
- Current Organic Chemistry
- Crystal structure, solution properties and hydrolytic activity of an alkoxo-bridged dinuclear copper(II) complex, as a ribonuclease model
(2002)
- Journal of the Chemical Society. Dalton Transactions
- The cleavage of RNA phosphodiester bonds by metal ions
(2002)
- Collection Symposium Series
- The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base sequence
(2002)
- Nucleic Acids Research
- Phosphodiester cleavage of ribonucleoside monophosphates and polyribonucleotides by homo- and heterodinuclear metal complexes of a cyclohexane-based polyamino-polyol ligand
(2003)
- Chemistry - A European Journal
- Preparation of hexaaza and heptaaza macrocycles functionalized with a single aminoalkyl pendant arm
(2003)
- Organic and Biomolecular Chemistry
- The base sequence dependent flexibility of linear single-stranded oligoribonucleotides correlates with the reactivity of the phosphodiester bond
(2003)
- Organic and Biomolecular Chemistry
- Hydrolysis of 2 ',3 '-O-methyleneadenos-5 '-yl bis(2 ',5 '-di-O-methylurid-3 '-yl) phosphate, a sugar O-alkylated trinucleoside 3 ',3 ',5 '-monophosphate: Implications for the mechanism of large ribozymes
(2004)
- Journal of Organic Chemistry
- Preparation of azacrown-functionalized 2 '-O-methyl oligoribonucleotides, potential artificial RNases
(2004)
- Bioconjugate Chemistry
- Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts
(2004)
- Organic and Biomolecular Chemistry