Publications (69)
Publication type
- Catalytically significant macrochelate formation in Zn2+ promoted hydrolysis of oligoribonucleotides: Model studies with chimeric phosphodiester/methylphosphonate oligomers
(1998)
- Nucleosides & nucleotides
- Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2 '-O-methylribooligonucleotides
(1998)
- Nucleic Acids Research
- The Cu2+-promoted cleavage of mRNA 5 '-cap analogs: A kinetic study with P-1-(7-methylguanosin-5 '-yl) P-3-(nucleosid-5 '-yl) triphospates and P-1-(7-methylguanosin-5 '-yl) P-4-(guanosin-5 '-yl) tetraphosphate
(1999)
- Nucleosides & nucleotides
- The mechanism of the metal ion promoted cleavage of RNA phosphodiester bonds involves a general acid catalysis by the metal aquo ion on the departure of the leaving group
(1999)
- Royal Society of Chemistry. Journal: Perkin Transactions 2
- Cleavage of the phosphodiester bond of uridylyl-(3 ',5 ')-8-carboxymethylaminoadenosine by hydronium, hydroxide and zinc(II) ions: A model study aimed at elucidating the potential of a carboxylate function as an intramolecular catalyst
(2000)
- Nucleosides, Nucleotides and Nucleic Acids
- Reactions of adenosine with bromo- and chloromalonaldehydes in aqueous solution: Kinetics and mechanism
(2000)
- European Journal of Organic Chemistry
- Synthesis of 2,6,10,14,18,22-hexaazaspiro[11.11]tricosane, the first example of a spiro aza crown derived from 2,2-bis(aminomethyl)propane-1,3-diamine
(2001)
- Tetrahedron Letters
- The cleavage of phosphodiester bonds within small RNA bulges in the presence and absence of metal ion catalysts
(2001)
- Journal of the Chemical Society, Perkin Transactions 2
- The effect of secondary structure on cleavage of the phosphodiester bonds of RNA
(2001)
- Cell Biochemistry and Biophysics
- A comparative study on the cleavage of stereoisomeric uridylyl(3 ',5 ')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts
(2002)
- Origins of Life and Evolution of Biospheres
- Crystal structure, solution properties and hydrolytic activity of an alkoxo-bridged dinuclear copper(II) complex, as a ribonuclease model
(2002)
- Journal of the Chemical Society. Dalton Transactions
- The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base sequence
(2002)
- Nucleic Acids Research
- Phosphodiester cleavage of ribonucleoside monophosphates and polyribonucleotides by homo- and heterodinuclear metal complexes of a cyclohexane-based polyamino-polyol ligand
(2003)
- Chemistry - A European Journal
- Preparation of hexaaza and heptaaza macrocycles functionalized with a single aminoalkyl pendant arm
(2003)
- Organic and Biomolecular Chemistry
- The base sequence dependent flexibility of linear single-stranded oligoribonucleotides correlates with the reactivity of the phosphodiester bond
(2003)
- Organic and Biomolecular Chemistry
- Hydrolysis of 2 ',3 '-O-methyleneadenos-5 '-yl bis(2 ',5 '-di-O-methylurid-3 '-yl) phosphate, a sugar O-alkylated trinucleoside 3 ',3 ',5 '-monophosphate: Implications for the mechanism of large ribozymes
(2004)
- Journal of Organic Chemistry
- Preparation of azacrown-functionalized 2 '-O-methyl oligoribonucleotides, potential artificial RNases
(2004)
- Bioconjugate Chemistry
- Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts
(2004)
- Organic and Biomolecular Chemistry
- Stabilisation of the transition state of phosphodiester bond cleavage within linear single-stranded oligoribonucleotides
(2004)
- Organic and Biomolecular Chemistry
- Hydrolysis of a mRNA 5 '-cap model substrate, 5 ',5 '-ApppA by di- and trinuclear zinc(II) complexes of a polyamino-polyol ligand
(2005)
- Journal of Inorganic Biochemistry
- Hydrolytic stability of 2 ',3 '-O-methyleneadenos-5 '-yl 2 ',5 '-di-O-methylurid-3 '-yl 5 '-O-methylurid-3 '(2 ')-yl phosphate: implications to feasibility of existence of phosphate-ranched RNA under physiological conditions
(2005)
- Organic and Biomolecular Chemistry
- Metal ion complexes of macrocyclic polyamines enhance both the phosphate hydrolysis and imidazole ring opening of RNA 5 '-cap structure
(2005)
- Chemistry and Biodiversity
- Polyazacyclophanes incorporating two pyridine units and a heteroaromatic pendant group as potential cleaving agents of mRNA F '-cap structure
(2005)
- Chemistry and Biodiversity
- A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites
(2010)
- BONE
- Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5 '-monophosphates bearing a biodegradable protecting group
(2010)
- Organic and Biomolecular Chemistry
- Oxidation of an Oligonucleotide-Bound Ce-III/Multiphosphonate Complex for Site-Selective DNA Scission
(2010)
- Chemistry - A European Journal
- Phosphorane intermediate vs. leaving group stabilization by intramolecular hydrogen bonding in the cleavage of trinucleoside monophosphates: implications for understanding catalysis by the large ribozymes
(2010)
- Organic and Biomolecular Chemistry
- Solid-Supported Synthesis and Click Conjugation of 4 '-C-Alkyne Functionalized Oligodeoxyribonucleotides
(2010)
- Bioconjugate Chemistry
- Synthesis of Oligonucleotide Glycoconjugates Using Sequential Click and Oximation Ligations
(2010)
- Bioconjugate Chemistry
- 3-Acetyloxy-2-cyano-2-(alkylaminocarbamoyl)propyl Groups as Biodegradable Protecting Groups of Nucleoside 5 '-mono-Phosphates
(2011)
- Molecules
- Involvement of the first transmembrane segment of human alpha(2)-adrenoceptors in the subtype-selective binding of chlorpromazine, spiperone and spiroxatrine
(2011)
- British Journal of Pharmacology
- Manipulation of Single-Stranded DNA by Using an Artificial Site-Selective DNA Cutter Composed of Cerium(IV)/EDTA and Phosphonate-Oligonucleotide Conjugates
(2011)
- Chemistry - An Asian Journal
- Solid-Supported 2 '-O-Glycoconjugation of Oligonucleotides by Azidation and Click Reactions
(2011)
- Bioconjugate Chemistry
- Synthesis and Enzymatic Deprotection of Biodegradably Protected Dinucleoside-2 ',5 '-monophosphates: 3-(Acetyloxy)-2,2-bis(ethoxycarbonyl)propyl Phosphoesters of 3 '-O-(Acyloxymethyl)adenylyl-2 ',5 '-adenosines
(2011)
- Chemistry and Biodiversity
- SYNTHESIS OF 7-SUBSTITUTED 3-beta-D-RIBOFURANOSYL-3H-IMIDAZO[2,1-i]PURINES
(2011)
- Collection of Czechoslovak Chemical Communications
- THE Zn2+ COMPLEX OF 1,4,7,10-TETRAAZACYCLODODECANE AS AN ARTIFICIAL NUCLEOBASE
(2011)
- Nucleosides, Nucleotides and Nucleic Acids
- 5 ',5 '-Phosphodiesters and esterase labile triesters of 2 '-C-methylribonucleosides
(2012)
- Arkivoc
- Acetylated and Methylated beta-Cyclodextrins as Viable Soluble Supports for the Synthesis of Short 2 '-Oligodeoxyribo-nucleotides in Solution
(2012)
- Molecules
- Characterization of phenolic compounds from inner bark of Betula pendula
(2012)
- Holzforschung
- Electrochemical incorporation of graphene oxide into conducting polymer films
(2012)
- Electrochimica Acta
- Electrochemical reduction of graphene oxide and its in situ spectroelectrochemical characterization
(2012)
- Physical Chemistry Chemical Physics
- Impact of steric constraints on the product distribution of phosphate-branched oligonucleotide models of the large ribozymes
(2012)
- Organic and Biomolecular Chemistry
- Intracomplex general acid/base catalyzed cleavage of RNA phosphodiester bonds: the leaving group effect
(2012)
- Organic and Biomolecular Chemistry
- Solid-Supported NOTA and DOTA Chelators Useful for the Synthesis of 3 '-Radiometalated Oligonucleotides
(2012)
- Bioconjugate Chemistry
- Synthesis and Enzymatic Deprotection of Fully Protected 2 '-5 ' Oligoadenylates (2-5A): Towards a Prodrug Strategy for Short 2-5A
(2012)
- Chemistry and Biodiversity
- Synthesis of 3',5'-Cyclic Phosphate and Thiophosphate Esters of 2'-C-Methyl Ribonucleosides
(2012)
- Helvetica Chimica Acta
- Synthesis of Biotinylated Multipodal Glycoclusters on a Solid Support
(2012)
- European Journal of Organic Chemistry
- Use of near-infrared radiation for oxygenic photosynthesis via photon up-conversion
(2012)
- International Journal of Hydrogen Energy
- 2,2-Disubstituted 4-acylthio-3-oxobutyl groups as esterase- and thermolabile protecting groups of phosphodiesters
(2013)
- Journal of Organic Chemistry
- 2,6-Bis(functionalized) purines as metal-ion-binding surrogate nucleobases that enhance hybridization with unmodified 2´-O-methyl oligoribonucleotides
(2013)
- Organic and Biomolecular Chemistry