Refereed review article in scientific journal (A2)
Pragmatic Approach on Neuroimaging Techniques for the Differential Diagnosis of Parkinsonisms
List of Authors: Peralta Cecilia, Strafella Antonio P., van Eimeren Thilo, Ceravolo Roberto, Seppi Klaus, Kaasinen Valtteri, Arena Julieta E., Lehericy Stephane; the International Parkinson Movement Disorders Society-Neuroimaging Study Group
Publisher: WILEY
Publication year: 2022
Journal: Movement Disorders Clinical Practice
Journal name in source: MOVEMENT DISORDERS CLINICAL PRACTICE
Journal acronym: MOV DISORD CLIN PRAC
Volume number: 9
Issue number: 1
Start page: 6
End page: 19
Number of pages: 14
ISSN: 2330-1619
eISSN: 2330-1619
DOI: http://dx.doi.org/10.1002/mdc3.13354
Self-archived copy’s web address: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721825/
Background Rapid advances in neuroimaging technologies in the exploration of the living human brain also apply to movement disorders. However, the accurate diagnosis of Parkinson's disease (PD) and atypical parkinsonian disorders (APDs) still remains a challenge in daily practice. Methods We review the literature and our own experience as the Movement Disorder Society-Neuroimaging Study Group in Movement Disorders with the aim of providing a practical approach to the use of imaging technologies in the clinical setting. Results The enormous amount of articles published so far and our increasing recognition of imaging technologies contrast with a lack of imaging protocols and updated algorithms for differential diagnosis. The distinctive pathological involvement in different brain structures and the correlation with imaging findings obtained with magnetic resonance, positron emission tomography, or single-photon emission computed tomography illustrate what qualitative and quantitative measures may be useful in the clinical setting. Conclusion We delineate a pragmatic approach to discuss imaging technologies, updated imaging algorithms, and their implications for differential diagnoses in PD and APDs.
