A Foundational Framework for Step-by-step Model Construction
: Barash Mikhail, Petre Ion
Publisher: IOS PRESS
: 2017
: Fundamenta Informaticae
: FUNDAMENTA INFORMATICAE
: FUND INFORM
: 154
: 1-4
: 15
: 24
: 10
: 0169-2968
DOI: https://doi.org/10.3233/FI-2017-1549
Constructing large biomodels de-novo is a computationally expensive process, requiring large sets of high-quality data. An alternative approach is to construct them from smaller existing models through various operations such as union, intersection, difference, and refinement. We introduce in this paper a foundational framework for biomodel construction capturing these operations, and we discuss some of their properties.