A2 Review article in a scientific journal

Coronary Computed Tomographic Angiography for Complete Assessment of Coronary Artery Disease: JACC State-of-the-Art Review




List of Authors: Serruys PW, Hara H, Garg S, Kawashima H, Norgaard BL, Dweck MR, Bax JJ, Knuuti J, Nieman K, Leipsic JA, Mushtaq S, Andreini D, Onuma Y

Publisher: ELSEVIER SCIENCE INC

Publication year: 2021

Journal: Journal of the American College of Cardiology

Journal name in source: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Journal acronym: J AM COLL CARDIOL

Volume number: 78

Issue number: 7

Number of pages: 24

ISSN: 0735-1097

DOI: http://dx.doi.org/10.1016/j.jacc.2021.06.019


Abstract

Coronary computed tomography angiography (CTA) has shown great technological improvements over the last 2 decades. High accuracy of CTA in detecting significant coronary stenosis has promoted CTA as a substitute for conven-tional invasive coronary angiography in patients with suspected coronary artery disease. In patients with coronary stenosis, CTA-derived physiological assessment is surrogate for intracoronary pressure and velocity wires, and renders possible decision-making about revascularization solely based on computed tomography. Computed tomography coro-nary anatomy with functionality assessment could potentially become a first line in diagnosis. Noninvasive imaging assessment of plaque burden and morphology is becoming a valuable substitute for intravascular imaging. Recently, wall shear stress and perivascular inflammation have been introduced. These assessments could support risk management for both primary and secondary cardiovascular prevention. Anatomy, functionality, and plaque composition by CTA tend to replace invasive assessment. Complete CTA assessment could provide a 1-stop-shop for diagnosis, risk management, and decision-making on treatment.


Last updated on 2021-14-10 at 15:30