A2 Refereed review article in a scientific journal

Electrodiffusion Phenomena in Neuroscience and the Nernst–Planck–Poisson Equations




AuthorsJasielec Jerzy J.

PublisherMDPI

Publishing placeBasel

Publication year2021

JournalElectrochem

Journal acronymElectrochem

Volume2

Issue2

First page 197

Last page215

DOIhttps://doi.org/10.3390/electrochem2020014

Web address https://www.mdpi.com/2673-3293/2/2/14

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/66858943


Abstract

This work is aimed to give an electrochemical insight into the ionic transport phenomena in the cellular environment of organized brain tissue. The Nernst–Planck–Poisson (NPP) model is presented, and its applications in the description of electrodiffusion phenomena relevant in nanoscale neurophysiology are reviewed. These phenomena include: the signal propagation in neurons, the liquid junction potential in extracellular space, electrochemical transport in ion channels, the electrical potential distortions invisible to patch-clamp technique, and calcium transport through mitochondrial membrane. The limitations, as well as the extensions of the NPP model that allow us to overcome these limitations, are also discussed. View Full-Text

Keywords: electrodiffusionNernst–Planck–Poissonneuroscienceneuronsliquid junction potentialionic channelspatch-clamp


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Last updated on 2024-26-11 at 22:34